ES459976A1 - Un procedimiento de preparacion de un ester de nitroxolina. - Google Patents

Un procedimiento de preparacion de un ester de nitroxolina.

Info

Publication number: ES459976A1
Authority: ES; Spain
Prior art keywords: poly; nitroxoline; antifungals; carboxylic; esters
Prior art date: 1976-06-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES459976A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Laboratoire Debat SA

Original Assignee

Laboratoire Debat SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-24

Filing date

1977-06-21

Publication date

1978-05-01

1977-06-21 Application filed by Laboratoire Debat SA filed Critical Laboratoire Debat SA

1978-05-01 Publication of ES459976A1 publication Critical patent/ES459976A1/es

Status Expired legal-status Critical Current

Links

RJIWZDNTCBHXAL-UHFFFAOYSA-N nitroxoline Chemical compound C1=CN=C2C(O)=CC=C([N+]([O-])=O)C2=C1 RJIWZDNTCBHXAL-UHFFFAOYSA-N 0.000 title abstract 5
239000002253 acid Substances 0.000 title abstract 3
229960005131 nitroxoline Drugs 0.000 title abstract 3
150000007513 acids Chemical class 0.000 title abstract 2
230000000844 anti-bacterial effect Effects 0.000 title abstract 2
229940088710 antibiotic agent Drugs 0.000 title abstract 2
229940121375 antifungal agent Drugs 0.000 title abstract 2
150000002148 esters Chemical class 0.000 title abstract 2
-1 5-nitroquinolin-8-yl Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
241000700159 Rattus Species 0.000 abstract 1
125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES459976A 1976-06-24 1977-06-21 Un procedimiento de preparacion de un ester de nitroxolina. Expired ES459976A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2639176		1976-06-24

Publications (1)

Publication Number	Publication Date
ES459976A1 true ES459976A1 (es)	1978-05-01

Family

ID=10242908

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES459976A Expired ES459976A1 (es)	1976-06-24	1977-06-21	Un procedimiento de preparacion de un ester de nitroxolina.

Country Status (5)

Country	Link
BE (1)	BE855851A (fr)
DE (1)	DE2728248A1 (fr)
ES (1)	ES459976A1 (fr)
FR (1)	FR2355829A1 (fr)
ZA (1)	ZA773797B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL136250A0 (en) *	1997-11-21	2001-05-20	Nps Pharma Inc	Metabotropic glutamate receptor antagonist compounds
US6429207B1 (en)	1997-11-21	2002-08-06	Nps Pharmaceuticals, Inc.	Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases
MX2021003724A (es) *	2018-09-29	2021-05-14	Jiangsu Yahong Meditech Co Ltd	Profarmaco de nitroxolina y su uso.
TWI874355B (zh) *	2020-02-14	2025-03-01	中國大陸商江蘇亞虹醫藥科技股份有限公司	硝羥喹啉前藥及其用途
CN111514142B (zh) *	2020-05-29	2021-04-06	江苏亚虹医药科技股份有限公司	含硝羟喹啉前药的药物组合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2237903A1 (de) *	1972-08-02	1974-03-28	Basf Ag	Gegen bakterien und pilze wirksame verbindungen

1977
- 1977-06-07 FR FR7717431A patent/FR2355829A1/fr not_active Withdrawn
- 1977-06-20 BE BE2056010A patent/BE855851A/fr unknown
- 1977-06-21 ES ES459976A patent/ES459976A1/es not_active Expired
- 1977-06-23 DE DE19772728248 patent/DE2728248A1/de active Pending
- 1977-06-24 ZA ZA00773797A patent/ZA773797B/xx unknown

Also Published As

Publication number	Publication date
FR2355829A1 (fr)	1978-01-20
DE2728248A1 (de)	1978-01-05
ZA773797B (en)	1978-05-30
BE855851A (fr)	1977-12-20

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