ES462076A1 - A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS. - Google Patents

A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS.

Info

Publication number
ES462076A1
ES462076A1 ES462076A ES462076A ES462076A1 ES 462076 A1 ES462076 A1 ES 462076A1 ES 462076 A ES462076 A ES 462076A ES 462076 A ES462076 A ES 462076A ES 462076 A1 ES462076 A1 ES 462076A1
Authority
ES
Spain
Prior art keywords
homosteroids
procedure
preparation
fluorine
chlorine atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462076A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES462076A1 publication Critical patent/ES462076A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un procedimiento para la preparación de D-homoesteroides de la fórmula general: ***(Ver fórmula ) en donde R6reresenta un átomo de hidrógeno, flúor o cloro o un grupo metílico; R9representa un átomo de hidrógeno, flúor o cloro; R17arepresenta un grupo de hidroxilo o aciloxilo con la salvedad de que, en donde R6 representa un átomo de nitrógeno en un compuesto 17a-hidroxílico, R9 debe representar un átomo de flúor o cloro.A procedure for the preparation of D-homosteroids of the general formula: ***(See formula) where R6represents a hydrogen, fluorine or chlorine atom or a methyl group; R9 represents a hydrogen, fluorine or chlorine atom; R17a represents a hydroxyl or acyloxy group with the proviso that, where R6 represents a nitrogen atom in a 17a-hydroxy compound, R9 must represent a fluorine or chlorine atom.

ES462076A 1976-09-03 1977-09-02 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS. Expired ES462076A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT656076A AT356301B (en) 1976-09-03 1976-09-03 METHOD FOR THE PRODUCTION OF NEW D-HOMOSTEROIDS

Publications (1)

Publication Number Publication Date
ES462076A1 true ES462076A1 (en) 1978-11-01

Family

ID=3587531

Family Applications (3)

Application Number Title Priority Date Filing Date
ES462076A Expired ES462076A1 (en) 1976-09-03 1977-09-02 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS.
ES469574A Expired ES469574A1 (en) 1976-09-03 1978-05-08 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS.
ES469573A Expired ES469573A1 (en) 1976-09-03 1978-05-08 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES469574A Expired ES469574A1 (en) 1976-09-03 1978-05-08 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS.
ES469573A Expired ES469573A1 (en) 1976-09-03 1978-05-08 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS.

Country Status (30)

Country Link
JP (1) JPS5910680B2 (en)
AR (1) AR220320A1 (en)
AT (1) AT356301B (en)
AU (1) AU516174B2 (en)
BE (1) BE858354A (en)
CA (1) CA1098897A (en)
CH (4) CH629827A5 (en)
DE (1) DE2738363A1 (en)
DK (1) DK140947B (en)
ES (3) ES462076A1 (en)
FI (1) FI57600C (en)
FR (1) FR2363580A1 (en)
GB (1) GB1586504A (en)
GR (1) GR73039B (en)
HK (1) HK26484A (en)
HU (2) HU184769B (en)
IE (1) IE45671B1 (en)
IL (1) IL52831A (en)
IT (1) IT1085032B (en)
LU (1) LU78064A1 (en)
MC (1) MC1166A1 (en)
MY (1) MY8500293A (en)
NL (1) NL182314C (en)
NO (1) NO145621C (en)
NZ (1) NZ185046A (en)
PH (1) PH14434A (en)
PT (1) PT66983B (en)
SE (1) SE440783B (en)
YU (2) YU40009B (en)
ZA (1) ZA775192B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1188616A (en) * 1981-06-11 1985-06-11 Hoffmann-La Roche Limited Pharmaceutical preparations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH571018A5 (en) * 1972-03-29 1975-12-31 Hoffmann La Roche
DK142289B (en) * 1973-03-28 1980-10-06 Hoffmann La Roche Analogous procedure for the preparation of D-homopregn-4-ene-3,20-dione.
DE2349023A1 (en) * 1973-09-26 1975-04-10 Schering Ag NEW D-HOMO-STEROIDS
CH601351A5 (en) * 1973-09-26 1978-07-14 Hoffmann La Roche
DE2349022A1 (en) * 1973-09-26 1975-04-10 Schering Ag NEW D-HOMO-STEROIDS
DE2442615A1 (en) * 1974-09-04 1976-03-18 Schering Ag NEW D-HOMO-STEROIDS

Also Published As

Publication number Publication date
LU78064A1 (en) 1978-10-17
CH629828A5 (en) 1982-05-14
FR2363580B1 (en) 1980-01-18
NO773057L (en) 1978-03-06
JPS5331655A (en) 1978-03-25
AR220320A1 (en) 1980-10-31
CH629827A5 (en) 1982-05-14
NZ185046A (en) 1980-10-08
NO145621B (en) 1982-01-18
SE440783B (en) 1985-08-19
ZA775192B (en) 1978-07-26
FR2363580A1 (en) 1978-03-31
HU176255B (en) 1981-01-28
IT1085032B (en) 1985-05-28
BE858354A (en) 1978-03-02
NL7709585A (en) 1978-03-07
DK140947B (en) 1979-12-10
DE2738363C2 (en) 1988-01-14
DE2738363A1 (en) 1978-03-16
IL52831A (en) 1982-04-30
IE45671L (en) 1978-03-03
FI772599A7 (en) 1978-03-04
GB1586504A (en) 1981-03-18
IL52831A0 (en) 1977-10-31
PT66983A (en) 1977-10-01
PH14434A (en) 1981-07-16
NO145621C (en) 1982-04-28
YU227782A (en) 1983-02-28
NL182314B (en) 1987-09-16
HK26484A (en) 1984-03-30
FI57600B (en) 1980-05-30
AU2830477A (en) 1979-03-08
CH629830A5 (en) 1982-05-14
CH629829A5 (en) 1982-05-14
YU40009B (en) 1985-06-30
YU200977A (en) 1983-02-28
ES469573A1 (en) 1978-12-01
DK140947C (en) 1980-05-27
MC1166A1 (en) 1978-06-02
ATA656076A (en) 1979-09-15
AU516174B2 (en) 1981-05-21
GR73039B (en) 1984-01-26
SE7709916L (en) 1978-03-04
NL182314C (en) 1988-02-16
YU40089B (en) 1985-06-30
PT66983B (en) 1979-09-12
CA1098897A (en) 1981-04-07
ES469574A1 (en) 1978-12-01
JPS5910680B2 (en) 1984-03-10
AT356301B (en) 1980-04-25
DK393277A (en) 1978-03-04
MY8500293A (en) 1985-12-31
FI57600C (en) 1980-09-10
IE45671B1 (en) 1982-10-20
HU184769B (en) 1984-10-29

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