ES462912A1 - Un procedimiento para la preparacion de nuevos derivados delacido acetil-salicilico. - Google Patents

Un procedimiento para la preparacion de nuevos derivados delacido acetil-salicilico.

Info

Publication number
ES462912A1
ES462912A1 ES462912A ES462912A ES462912A1 ES 462912 A1 ES462912 A1 ES 462912A1 ES 462912 A ES462912 A ES 462912A ES 462912 A ES462912 A ES 462912A ES 462912 A1 ES462912 A1 ES 462912A1
Authority
ES
Spain
Prior art keywords
inflammatory properties
glycerides
benzodioxan
moiety
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462912A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of ES462912A1 publication Critical patent/ES462912A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un procedimiento para la preparación de nuevos derivados del ácido acetilsalicílico de fórmula **(Fórmula)** Donde cada radical R es un grupo alquilo de 1 a 15 átomos de carbono, cuyo procedimiento se caracteriza por hacer reaccionar cloruro de acetilsalidiloilo con un diéster glicerólico de fórmula ROCOCH2CHOHCH2OCOR, donde R es un grupo alquilo de 1 a 15 átomos de carbono, en presencia de un disolvente orgánico inerte, a una temperatura comprendida entre la ambiente y el punto de ebullición de la mezcla de reacción.
ES462912A 1976-10-28 1977-10-04 Un procedimiento para la preparacion de nuevos derivados delacido acetil-salicilico. Expired ES462912A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/736,633 US4046887A (en) 1976-10-28 1976-10-28 Glycerides with anti-inflammatory properties

Publications (1)

Publication Number Publication Date
ES462912A1 true ES462912A1 (es) 1978-12-16

Family

ID=24960642

Family Applications (1)

Application Number Title Priority Date Filing Date
ES462912A Expired ES462912A1 (es) 1976-10-28 1977-10-04 Un procedimiento para la preparacion de nuevos derivados delacido acetil-salicilico.

Country Status (9)

Country Link
US (1) US4046887A (es)
JP (1) JPS5356674A (es)
AR (1) AR215650A1 (es)
AU (1) AU507102B2 (es)
DE (1) DE2748291C3 (es)
ES (1) ES462912A1 (es)
FR (1) FR2369276A1 (es)
GR (1) GR63728B (es)
PH (1) PH12665A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5742680A (en) * 1980-08-29 1982-03-10 Bago Sa Labor Novel ester of substituted benzoic acid and manufacture
IT1142016B (it) * 1981-05-07 1986-10-08 Medea Res Srl Derivato del 2,4-diossacicloesanone
FI821903A7 (fi) * 1981-06-10 1982-12-11 Dr Lo Zambeletti S P A Uusi menetelmä 3-metyyli-3-(o- metoksifenoksi)-bentso-2,4- dioksasykloheksanonin valmistamiseksi.
CA1176644A (en) * 1982-03-24 1984-10-23 Neil E. Bateman Pharmaceutical compound and process for the manufacture thereof
US4546197A (en) * 1982-03-24 1985-10-08 R. P. Scherer Corporation Pharmaceutical composition and process for the manufacture thereof
EP0272223B1 (en) * 1987-02-05 1991-05-29 FARMACEUTICI CABER S.p.A. 4-oxo-1,3-benzodioxane derivative
US7109326B2 (en) * 1997-04-15 2006-09-19 Genentech, Inc. Halo-alkoxycarbonyl prodrugs
WO2008101173A2 (en) * 2007-02-16 2008-08-21 Cornell University Biodegradable compositions and materials

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3420830A (en) * 1966-07-11 1969-01-07 Syntex Corp 4-keto-1,3-benzodioxane and 4-keto-1,3-benzooxazine derivatives
US3741985A (en) * 1971-01-21 1973-06-26 Syntex Corp Phenyl-benzodioxane derivatives

Also Published As

Publication number Publication date
AU2877877A (en) 1979-03-22
FR2369276A1 (fr) 1978-05-26
PH12665A (en) 1979-07-11
AU507102B2 (en) 1980-01-31
FR2369276B1 (es) 1980-06-27
US4046887A (en) 1977-09-06
JPS5356674A (en) 1978-05-23
AR215650A1 (es) 1979-10-31
JPS5510590B2 (es) 1980-03-17
DE2748291B2 (de) 1979-03-01
DE2748291C3 (de) 1979-10-25
GR63728B (en) 1979-12-03
DE2748291A1 (de) 1978-05-03

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