ES464780A1 - Reduction of 2,5 - diketogluconic acid - Google Patents

Reduction of 2,5 - diketogluconic acid

Info

Publication number
ES464780A1
ES464780A1 ES464780A ES464780A ES464780A1 ES 464780 A1 ES464780 A1 ES 464780A1 ES 464780 A ES464780 A ES 464780A ES 464780 A ES464780 A ES 464780A ES 464780 A1 ES464780 A1 ES 464780A1
Authority
ES
Spain
Prior art keywords
formula
ammonium
alkali metal
alkaline earth
alkyl ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES464780A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/843,946 external-priority patent/US4159990A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES464780A1 publication Critical patent/ES464780A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals
    • C07H7/027—Keto-aldonic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Seasonings (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

Un procedimiento para preparar una mezcla de ácido-2-cetugulónico de la fórmula **fórmula** o de un éster alquílico de C1-4 o de una sal de metal alcalino, de metal alcalinotérreo, de amonio o de tetraalquil-(C1-4)-amonio del mismo, y 2-cetogluconato de la fórmula**fórmula** o un éster alquílico de C1-4 o una sal de metal alcalino, de metal alcalinotérreo, de amonio o de tetraalquil (C1-4)-amonio del mismo, cuyo procedimiento comprende reducir ácido 2,5- dicetoglucónico de la fórmula **fórmula ** o un éster alquílico de C1-4 o una sal de metal alcalino, de metal alcalinotérreo, de amonio o de tetraalquil (C1-4)-amonio del mismo, por reacción con un borohidruro de metal alcalino, efectuándose la reacción mediante la utilización de aproximadamente 0,8 a 1,1 equivalentes por mol de un borohidruro de metal alcalino en solución, a un pH mayor que 5 y a una temperatura comprendida entre aproximadamente -30ºC y 50ºC.A process for preparing a mixture of 2-cetugulonic acid of the formula **formula** or of a C1-4 alkyl ester or of an alkali metal, alkaline earth metal, ammonium or tetraalkyl-(C1- 4)-ammonium thereof, and 2-ketogluconate of the formula**formula** or a C1-4 alkyl ester or an alkali metal, alkaline earth metal, ammonium or tetra(C1-4)alkyl ammonium salt thereof, which process comprises reducing 2,5-diketogluconic acid of the formula **formula ** or a C1-4 alkyl ester or an alkali metal, alkaline earth metal, ammonium or tetraalkyl (C1-4) salt -ammonium thereof, by reaction with an alkali metal borohydride, the reaction being effected by using about 0.8 to 1.1 equivalents per mole of an alkali metal borohydride in solution, at a pH greater than 5 and at a temperature between about -30°C and 50°C.

ES464780A 1976-12-10 1977-12-06 Reduction of 2,5 - diketogluconic acid Expired ES464780A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74950976A 1976-12-10 1976-12-10
US05/843,946 US4159990A (en) 1976-12-10 1977-10-20 Reduction of 2,5-diketogluconic acid

Publications (1)

Publication Number Publication Date
ES464780A1 true ES464780A1 (en) 1979-06-01

Family

ID=27115134

Family Applications (1)

Application Number Title Priority Date Filing Date
ES464780A Expired ES464780A1 (en) 1976-12-10 1977-12-06 Reduction of 2,5 - diketogluconic acid

Country Status (29)

Country Link
JP (1) JPS5384916A (en)
AR (1) AR218278A1 (en)
AT (1) AT354470B (en)
AU (1) AU498866B1 (en)
BR (1) BR7708220A (en)
CA (1) CA1110637A (en)
CH (1) CH629470A5 (en)
CS (1) CS208738B2 (en)
DD (1) DD135204A5 (en)
DE (1) DE2754719C3 (en)
DK (1) DK157139C (en)
ES (1) ES464780A1 (en)
FI (1) FI773722A7 (en)
FR (1) FR2373511A1 (en)
GB (1) GB1561324A (en)
HU (1) HU178688B (en)
IE (1) IE46106B1 (en)
IT (1) IT1192212B (en)
LU (1) LU78666A1 (en)
MX (1) MX4533E (en)
NL (1) NL170288C (en)
NO (1) NO774233L (en)
NZ (1) NZ185917A (en)
PH (1) PH13701A (en)
PL (1) PL114409B1 (en)
PT (1) PT67381B (en)
SE (1) SE7713979L (en)
TR (1) TR19706A (en)
YU (1) YU285077A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154649C (en) * 1978-12-01 1989-05-08 Pfizer METHOD FOR PREPARING 2-KETOGULONIC ACID

Also Published As

Publication number Publication date
CS208738B2 (en) 1981-09-15
NZ185917A (en) 1980-03-05
IE46106B1 (en) 1983-02-23
HU178688B (en) 1982-06-28
SE7713979L (en) 1978-06-11
NL170288C (en) 1982-10-18
IT1192212B (en) 1988-03-31
JPS569495B2 (en) 1981-03-02
BR7708220A (en) 1978-08-15
PL114409B1 (en) 1981-01-31
LU78666A1 (en) 1979-06-13
JPS5384916A (en) 1978-07-26
CA1110637A (en) 1981-10-13
TR19706A (en) 1979-10-11
DE2754719C3 (en) 1980-11-20
MX4533E (en) 1982-06-03
PH13701A (en) 1980-09-08
CH629470A5 (en) 1982-04-30
NL7713365A (en) 1978-06-13
YU285077A (en) 1982-08-31
FR2373511B1 (en) 1980-06-06
AT354470B (en) 1979-01-10
PT67381A (en) 1978-01-01
DK549477A (en) 1978-06-11
FI773722A7 (en) 1978-06-11
PT67381B (en) 1979-05-18
PL202800A1 (en) 1978-08-28
NO774233L (en) 1978-06-13
DD135204A5 (en) 1979-04-18
NL170288B (en) 1982-05-17
DK157139C (en) 1990-04-16
IE46106L (en) 1978-06-10
ATA882177A (en) 1979-06-15
GB1561324A (en) 1980-02-20
AR218278A1 (en) 1980-05-30
FR2373511A1 (en) 1978-07-07
DE2754719B2 (en) 1980-03-27
DK157139B (en) 1989-11-13
AU498866B1 (en) 1979-03-29
DE2754719A1 (en) 1978-06-15

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