ES465346A1 - Procedimiento para preparar imidazoles 4,5-disustituidos. - Google Patents

Procedimiento para preparar imidazoles 4,5-disustituidos.

Info

Publication number
ES465346A1
ES465346A1 ES465346A ES465346A ES465346A1 ES 465346 A1 ES465346 A1 ES 465346A1 ES 465346 A ES465346 A ES 465346A ES 465346 A ES465346 A ES 465346A ES 465346 A1 ES465346 A1 ES 465346A1
Authority
ES
Spain
Prior art keywords
imidazoles
disstituted
prepare
procedure
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES465346A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of ES465346A1 publication Critical patent/ES465346A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/42—One oxygen atom attached in position 5

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Procedimiento para preparar imidazoles 45-disustituidosde fórmula:***(ver formula )***en la que R es metilo o etilo; n es 234 ó 5; Q es hidrógeno o un grupo aroílo; y sus sales de adición de ácido; caracterizado porque comprende disulfurar un compuesto de fórmula:***(ver formula)***En la que Rn y Q se definen como anteriormente.
ES465346A 1976-12-22 1977-12-22 Procedimiento para preparar imidazoles 4,5-disustituidos. Expired ES465346A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB53538/76A GB1596376A (en) 1976-12-22 1976-12-22 4,5-disubstituted imidazole-2-thiones processes for their preparation and their use as intermediates

Publications (1)

Publication Number Publication Date
ES465346A1 true ES465346A1 (es) 1978-09-16

Family

ID=10468162

Family Applications (1)

Application Number Title Priority Date Filing Date
ES465346A Expired ES465346A1 (es) 1976-12-22 1977-12-22 Procedimiento para preparar imidazoles 4,5-disustituidos.

Country Status (21)

Country Link
US (1) US4166184A (es)
JP (1) JPS5379863A (es)
AU (1) AU514770B2 (es)
BE (1) BE862095A (es)
CA (1) CA1096388A (es)
DE (1) DE2755749A1 (es)
DK (1) DK559877A (es)
ES (1) ES465346A1 (es)
FI (1) FI773592A7 (es)
FR (1) FR2375219A1 (es)
GB (1) GB1596376A (es)
HU (1) HU177745B (es)
IE (1) IE46493B1 (es)
IL (1) IL53350A (es)
LU (1) LU78725A1 (es)
NL (1) NL7714261A (es)
NO (1) NO774407L (es)
PH (1) PH14357A (es)
PT (1) PT67276B (es)
SE (1) SE7714123L (es)
ZA (1) ZA776538B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170872B1 (de) * 1984-07-13 1989-08-23 Bayer Ag Verfahren zur Herstellung, von 3,7-Bisacetaminoheptanon-2
EP0428849A3 (en) * 1989-09-28 1991-07-31 Hoechst Aktiengesellschaft Retroviral protease inhibitors
US7767826B2 (en) * 2007-10-05 2010-08-03 Pharmatech International, Inc. Process for the synthesis of L-(+)-ergothioneine
CN109956881A (zh) * 2017-12-26 2019-07-02 上海凯赛生物技术研发中心有限公司 一种苯甲酰戊二胺及其制备和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2585388A (en) * 1948-11-17 1952-02-12 Lilly Co Eli Preparation of 2-mercaptoimidazoles
GB1054708A (es) * 1964-10-02

Also Published As

Publication number Publication date
NO774407L (no) 1978-06-23
JPS5379863A (en) 1978-07-14
PH14357A (en) 1981-06-03
ZA776538B (en) 1978-08-30
SE7714123L (sv) 1978-06-23
HU177745B (en) 1981-12-28
FR2375219A1 (fr) 1978-07-21
GB1596376A (en) 1981-08-26
IL53350A (en) 1981-10-30
PT67276B (en) 1979-04-18
IE46493B1 (en) 1983-06-29
AU514770B2 (en) 1981-02-26
PT67276A (en) 1977-12-01
NL7714261A (nl) 1978-06-26
BE862095A (fr) 1978-06-21
IE46493L (en) 1978-06-22
CA1096388A (en) 1981-02-24
IL53350A0 (en) 1978-01-31
DK559877A (da) 1978-06-23
AU3157277A (en) 1979-06-21
FR2375219B1 (es) 1981-02-27
US4166184A (en) 1979-08-28
LU78725A1 (es) 1978-04-17
DE2755749A1 (de) 1978-06-29
FI773592A7 (fi) 1978-06-23

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