ES467435A1 - Procedimiento para la obtencion de derivados de pregnano po-lihalogenados - Google Patents
Procedimiento para la obtencion de derivados de pregnano po-lihalogenadosInfo
- Publication number
- ES467435A1 ES467435A1 ES467435A ES467435A ES467435A1 ES 467435 A1 ES467435 A1 ES 467435A1 ES 467435 A ES467435 A ES 467435A ES 467435 A ES467435 A ES 467435A ES 467435 A1 ES467435 A1 ES 467435A1
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- halogenopregnadiene
- novel
- production
- pregna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000003126 pregnane derivatives Polymers 0.000 abstract 1
- 150000003128 pregnanes Polymers 0.000 abstract 1
- 229940070710 valerate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la obtención de derivados de pregnano polihalogenados de fórmula-01 (I): **(Fórmula-01)** donde X significa flúor o cloro y R significa un grupo hidroxi libre o esterificado, o cloro, caracterizado porque un compuesto de fórmula-02 (II): **(Fórmula-02)** donde R tiene el mismo significado como indicado para la fórmula (I), se trata con ácido subclórico o un medio cededor de ácido subclórico, y, si se desea, en los compuestos obtenidos con un grupo hidroxi R esterificado en la posición 21, éste se transforma en forma en sí conocida en el grupo hidroxi libre y/o un grupo hidroxi R libre se esterifica en forma en sí conocida, y/o, si se desea, los hemiésteres de los ácidos dicarboxílicos o de ácidos inorgánicos polibásicos se transforman en sus sales de metal o sales de bases orgánicas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH225476 | 1976-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES467435A1 true ES467435A1 (es) | 1979-09-01 |
Family
ID=4229470
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456135A Expired ES456135A1 (es) | 1976-02-24 | 1977-02-22 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados. |
| ES467436A Expired ES467436A1 (es) | 1976-02-24 | 1978-03-01 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados |
| ES467437A Expired ES467437A1 (es) | 1976-02-24 | 1978-03-01 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados. |
| ES467435A Expired ES467435A1 (es) | 1976-02-24 | 1978-03-01 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados |
| ES467438A Expired ES467438A1 (es) | 1976-02-24 | 1978-03-01 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456135A Expired ES456135A1 (es) | 1976-02-24 | 1977-02-22 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados. |
| ES467436A Expired ES467436A1 (es) | 1976-02-24 | 1978-03-01 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados |
| ES467437A Expired ES467437A1 (es) | 1976-02-24 | 1978-03-01 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES467438A Expired ES467438A1 (es) | 1976-02-24 | 1978-03-01 | Procedimiento para la obtencion de derivados de pregnano po-lihalogenados |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS52102265A (es) |
| AT (1) | ATA119377A (es) |
| AU (1) | AU2257377A (es) |
| BE (1) | BE851726A (es) |
| DD (1) | DD129653A5 (es) |
| DE (1) | DE2707346A1 (es) |
| DK (1) | DK78977A (es) |
| ES (5) | ES456135A1 (es) |
| FR (1) | FR2342303A1 (es) |
| IL (1) | IL51524A0 (es) |
| NL (1) | NL7701324A (es) |
| NZ (1) | NZ183417A (es) |
| SE (1) | SE7702000L (es) |
| ZA (1) | ZA771088B (es) |
-
1977
- 1977-01-21 DD DD7700197484A patent/DD129653A5/xx unknown
- 1977-02-08 NL NL7701324A patent/NL7701324A/xx not_active Application Discontinuation
- 1977-02-19 DE DE19772707346 patent/DE2707346A1/de active Pending
- 1977-02-22 ES ES456135A patent/ES456135A1/es not_active Expired
- 1977-02-22 FR FR7705054A patent/FR2342303A1/fr active Granted
- 1977-02-23 AU AU22573/77A patent/AU2257377A/en not_active Expired
- 1977-02-23 IL IL51524A patent/IL51524A0/xx unknown
- 1977-02-23 ZA ZA00771088A patent/ZA771088B/xx unknown
- 1977-02-23 SE SE7702000A patent/SE7702000L/xx unknown
- 1977-02-23 AT AT119377A patent/ATA119377A/de not_active IP Right Cessation
- 1977-02-23 DK DK78977A patent/DK78977A/da not_active Application Discontinuation
- 1977-02-23 BE BE175170A patent/BE851726A/xx unknown
- 1977-02-23 NZ NZ183417A patent/NZ183417A/xx unknown
- 1977-02-24 JP JP1874477A patent/JPS52102265A/ja active Pending
-
1978
- 1978-03-01 ES ES467436A patent/ES467436A1/es not_active Expired
- 1978-03-01 ES ES467437A patent/ES467437A1/es not_active Expired
- 1978-03-01 ES ES467435A patent/ES467435A1/es not_active Expired
- 1978-03-01 ES ES467438A patent/ES467438A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2342303B1 (es) | 1979-03-09 |
| AU2257377A (en) | 1978-08-31 |
| ES467438A1 (es) | 1979-09-01 |
| IL51524A0 (en) | 1977-04-29 |
| NZ183417A (en) | 1979-12-11 |
| DE2707346A1 (de) | 1977-08-25 |
| ZA771088B (en) | 1978-01-25 |
| DD129653A5 (de) | 1978-02-01 |
| NL7701324A (nl) | 1977-08-26 |
| ES467437A1 (es) | 1980-01-16 |
| FR2342303A1 (fr) | 1977-09-23 |
| ES456135A1 (es) | 1978-05-01 |
| BE851726A (fr) | 1977-08-23 |
| ATA119377A (de) | 1979-08-15 |
| DK78977A (da) | 1977-08-25 |
| SE7702000L (sv) | 1977-08-25 |
| ES467436A1 (es) | 1979-10-01 |
| JPS52102265A (en) | 1977-08-27 |
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