ES469004A1 - Un procedimiento para la preparacion de nuevos derivados de somatostatina - Google Patents

Un procedimiento para la preparacion de nuevos derivados de somatostatina

Info

Publication number: ES469004A1
Authority: ES; Spain
Prior art keywords: phe; hydrogen; cys; thr; lys
Prior art date: 1977-04-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES469004A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-04-21

Filing date

1978-04-20

Publication date

1979-09-01

1978-02-01 Priority claimed from US04/874,173 external-priority patent/US4151394A/en

1978-04-20 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1979-09-01 Publication of ES469004A1 publication Critical patent/ES469004A1/es

Status Expired legal-status Critical Current

Links

102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
125000006239 protecting group Chemical group 0.000 abstract 3
QNAYBMKLOCPYGJ-UWTATZPHSA-N D-alanine Chemical group C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 2
125000003558 D-valino group Chemical group C(=O)(O)[C@@H](C(C)C)N* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 1
125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

ES469004A 1977-04-21 1978-04-20 Un procedimiento para la preparacion de nuevos derivados de somatostatina Expired ES469004A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US78947377A	1977-04-21	1977-04-21
US04/874,173 US4151394A (en)	1978-02-01	1978-02-01	Guidance system for arc welder

Publications (1)

Publication Number	Publication Date
ES469004A1 true ES469004A1 (es)	1979-09-01

Family

ID=27120917

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES469004A Expired ES469004A1 (es)	1977-04-21	1978-04-20	Un procedimiento para la preparacion de nuevos derivados de somatostatina
ES476913A Expired ES476913A1 (es)	1977-04-21	1979-01-16	Un procedimiento para la preparacion de nuevos derivados de somatostatina.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES476913A Expired ES476913A1 (es)	1977-04-21	1979-01-16	Un procedimiento para la preparacion de nuevos derivados de somatostatina.

Country Status (23)

Country	Link
JP (1)	JPS53132589A (da)
AR (1)	AR229798A1 (da)
AT (1)	AT360675B (da)
AU (1)	AU518731B2 (da)
BG (2)	BG28704A3 (da)
CA (1)	CA1120030A (da)
CH (1)	CH634040A5 (da)
DD (1)	DD136739A5 (da)
DE (1)	DE2816855A1 (da)
DK (1)	DK174178A (da)
EG (1)	EG14800A (da)
ES (2)	ES469004A1 (da)
FI (1)	FI64575C (da)
FR (1)	FR2387942A1 (da)
GB (1)	GB1596329A (da)
GR (1)	GR69789B (da)
IE (1)	IE46617B1 (da)
IL (1)	IL54532A (da)
IT (1)	IT1094471B (da)
NL (1)	NL7804219A (da)
NZ (1)	NZ187010A (da)
PT (1)	PT67912B (da)
SE (1)	SE7804398L (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8423431D0 (en) *	1984-09-17	1984-10-24	Sandoz Ltd	Organic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2608336A1 (de) *	1975-03-11	1976-09-30	Sandoz Ag	Neue organische verbindungen, ihre herstellung und verwendung
US4372884A (en) *	1975-08-06	1983-02-08	The Salk Institute For Biological Studies	Pharmaceutically active peptides

1978
- 1978-04-17 GB GB14917/78A patent/GB1596329A/en not_active Expired
- 1978-04-18 FI FI781183A patent/FI64575C/fi not_active IP Right Cessation
- 1978-04-18 NZ NZ187010A patent/NZ187010A/xx unknown
- 1978-04-18 IL IL54532A patent/IL54532A/xx unknown
- 1978-04-18 DE DE19782816855 patent/DE2816855A1/de not_active Withdrawn
- 1978-04-18 SE SE7804398A patent/SE7804398L/xx unknown
- 1978-04-18 JP JP4621478A patent/JPS53132589A/ja active Pending
- 1978-04-18 AR AR271821A patent/AR229798A1/es active
- 1978-04-18 PT PT67912A patent/PT67912B/pt unknown
- 1978-04-19 IE IE766/78A patent/IE46617B1/en unknown
- 1978-04-19 FR FR7811581A patent/FR2387942A1/fr active Granted
- 1978-04-19 EG EG265/78A patent/EG14800A/xx active
- 1978-04-19 CA CA000301485A patent/CA1120030A/en not_active Expired
- 1978-04-19 GR GR56031A patent/GR69789B/el unknown
- 1978-04-20 AT AT282978A patent/AT360675B/de not_active IP Right Cessation
- 1978-04-20 CH CH425878A patent/CH634040A5/de not_active IP Right Cessation
- 1978-04-20 ES ES469004A patent/ES469004A1/es not_active Expired
- 1978-04-20 NL NL7804219A patent/NL7804219A/xx not_active Application Discontinuation
- 1978-04-20 IT IT22553/78A patent/IT1094471B/it active
- 1978-04-20 DK DK174178A patent/DK174178A/da active IP Right Grant
- 1978-04-21 BG BG039504A patent/BG28704A3/xx unknown
- 1978-04-21 DD DD78204949A patent/DD136739A5/xx unknown
- 1978-04-21 AU AU35341/78A patent/AU518731B2/en not_active Expired
- 1978-04-21 BG BG040964A patent/BG28705A4/xx unknown
1979
- 1979-01-16 ES ES476913A patent/ES476913A1/es not_active Expired

Also Published As

Publication number	Publication date
GR69789B (da)	1982-07-07
IL54532A0 (en)	1978-07-31
NL7804219A (nl)	1978-10-24
IL54532A (en)	1983-03-31
BG28705A4 (bg)	1980-06-16
IE46617B1 (en)	1983-08-10
FR2387942A1 (fr)	1978-11-17
AU3534178A (en)	1979-10-25
SE7804398L (sv)	1978-10-22
GB1596329A (en)	1981-08-26
IT1094471B (it)	1985-08-02
PT67912B (en)	1979-11-14
ATA282978A (de)	1980-06-15
AR229798A1 (es)	1983-11-30
ES476913A1 (es)	1979-09-16
AT360675B (de)	1981-01-26
CA1120030A (en)	1982-03-16
EG14800A (en)	1985-06-30
IE780766L (en)	1978-10-21
FI781183A7 (fi)	1978-10-22
DE2816855A1 (de)	1978-11-02
DD136739A5 (de)	1979-07-25
NZ187010A (en)	1980-08-26
FI64575C (fi)	1983-12-12
AU518731B2 (en)	1981-10-15
JPS53132589A (en)	1978-11-18
IT7822553A0 (it)	1978-04-20
FR2387942B1 (da)	1981-06-26
FI64575B (fi)	1983-08-31
BG28704A3 (bg)	1980-06-16
PT67912A (en)	1978-05-01
CH634040A5 (en)	1983-01-14
DK174178A (da)	1978-10-22

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Legal Events

Date	Code	Title	Description
2000-05-01	FD1A	Patent lapsed	Effective date: 20000301