ES470343A1 - Proceso para la preparacion del ester tetra-nicotinico de lapapaverolina - Google Patents
Proceso para la preparacion del ester tetra-nicotinico de lapapaverolinaInfo
- Publication number
- ES470343A1 ES470343A1 ES470343A ES470343A ES470343A1 ES 470343 A1 ES470343 A1 ES 470343A1 ES 470343 A ES470343 A ES 470343A ES 470343 A ES470343 A ES 470343A ES 470343 A1 ES470343 A1 ES 470343A1
- Authority
- ES
- Spain
- Prior art keywords
- papaveroline
- tetranicotinic
- ester
- production
- paperveroline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- MXQKCNCLQIHHJA-UHFFFAOYSA-N papaveroline Chemical compound C1=C(O)C(O)=CC=C1CC1=NC=CC2=CC(O)=C(O)C=C12 MXQKCNCLQIHHJA-UHFFFAOYSA-N 0.000 title abstract 2
- 229950005542 papaveroline Drugs 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title 1
- 200000000007 Arterial disease Diseases 0.000 abstract 1
- MSYBLBLAMDYKKZ-UHFFFAOYSA-N hydron;pyridine-3-carbonyl chloride;chloride Chemical compound Cl.ClC(=O)C1=CC=CN=C1 MSYBLBLAMDYKKZ-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT24141/77A IT1143667B (it) | 1977-05-30 | 1977-05-30 | Derivato paraverolinico ad azione duratura e procedimento per ottenerlo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES470343A1 true ES470343A1 (es) | 1979-01-01 |
Family
ID=11212187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES470343A Expired ES470343A1 (es) | 1977-05-30 | 1978-05-30 | Proceso para la preparacion del ester tetra-nicotinico de lapapaverolina |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS53149982A (fr) |
| BE (1) | BE867515A (fr) |
| BR (1) | BR7803416A (fr) |
| CA (1) | CA1084504A (fr) |
| CH (1) | CH633446A5 (fr) |
| DE (1) | DE2822186A1 (fr) |
| ES (1) | ES470343A1 (fr) |
| FR (1) | FR2392987A1 (fr) |
| GB (1) | GB1593598A (fr) |
| GR (1) | GR63731B (fr) |
| IT (1) | IT1143667B (fr) |
| MX (1) | MX5515E (fr) |
| PT (1) | PT68115A (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI77027C (fi) * | 1979-07-19 | 1989-01-10 | Andre Buzas | Saett framstaellning av farmakologiskt verksam 1-/1-(3,4-dimetoxifenyl)-3-amino-propyl/-6,7-dimetoxi- isokinolinfoerening. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1175246B (de) * | 1959-12-14 | 1964-08-06 | Orsymonde Fa | Verfahren zur Herstellung des Dimethylpapa-verolin-bis-nicotinsaeureesters und seines sauren Dimaleats |
| FR794M (fr) * | 1960-12-02 | 1961-09-11 |
-
1977
- 1977-05-30 IT IT24141/77A patent/IT1143667B/it active
-
1978
- 1978-05-20 DE DE19782822186 patent/DE2822186A1/de not_active Withdrawn
- 1978-05-24 GB GB21857/78A patent/GB1593598A/en not_active Expired
- 1978-05-26 BE BE188060A patent/BE867515A/fr not_active IP Right Cessation
- 1978-05-29 BR BR7803416A patent/BR7803416A/pt unknown
- 1978-05-29 MX MX787104U patent/MX5515E/es unknown
- 1978-05-29 GR GR56361A patent/GR63731B/el unknown
- 1978-05-30 JP JP6483078A patent/JPS53149982A/ja active Granted
- 1978-05-30 ES ES470343A patent/ES470343A1/es not_active Expired
- 1978-05-30 CA CA304,384A patent/CA1084504A/fr not_active Expired
- 1978-05-30 PT PT68115A patent/PT68115A/pt unknown
- 1978-05-30 CH CH587778A patent/CH633446A5/it not_active IP Right Cessation
- 1978-05-30 FR FR7816137A patent/FR2392987A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2392987A1 (fr) | 1978-12-29 |
| IT1143667B (it) | 1986-10-22 |
| MX5515E (es) | 1983-09-14 |
| BR7803416A (pt) | 1979-01-02 |
| FR2392987B1 (fr) | 1982-04-23 |
| GB1593598A (en) | 1981-07-22 |
| JPS572715B2 (fr) | 1982-01-18 |
| BE867515A (fr) | 1978-09-18 |
| CA1084504A (fr) | 1980-08-26 |
| DE2822186A1 (de) | 1978-12-14 |
| PT68115A (en) | 1978-06-01 |
| CH633446A5 (en) | 1982-12-15 |
| GR63731B (en) | 1979-12-04 |
| JPS53149982A (en) | 1978-12-27 |
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