ES471297A1 - Un procedimiento para la obtencion de 3-((s)-1'feniletilami-no) propilamino-bleomicina - Google Patents
Un procedimiento para la obtencion de 3-((s)-1'feniletilami-no) propilamino-bleomicinaInfo
- Publication number
- ES471297A1 ES471297A1 ES471297A ES471297A ES471297A1 ES 471297 A1 ES471297 A1 ES 471297A1 ES 471297 A ES471297 A ES 471297A ES 471297 A ES471297 A ES 471297A ES 471297 A1 ES471297 A1 ES 471297A1
- Authority
- ES
- Spain
- Prior art keywords
- medium
- bleomycin
- diaminopropane
- phenylethyl
- precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OYVAGSVQBOHSSS-UAPAGMARSA-O bleomycin A2 Chemical class N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-UAPAGMARSA-O 0.000 abstract 4
- 108010006654 Bleomycin Proteins 0.000 abstract 3
- 241000233866 Fungi Species 0.000 abstract 2
- 241000187747 Streptomyces Species 0.000 abstract 2
- 229960001561 bleomycin Drugs 0.000 abstract 2
- 230000003327 cancerostatic effect Effects 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 241001147844 Streptomyces verticillus Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- NQONXAAXIFYYMX-JTQLQIEISA-N n'-[(1s)-1-phenylethyl]propane-1,3-diamine Chemical compound NCCCN[C@@H](C)C1=CC=CC=C1 NQONXAAXIFYYMX-JTQLQIEISA-N 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 208000005069 pulmonary fibrosis Diseases 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
Perfeccionamientos en los aparatos con su correspondiente procedimiento para la fabricación de cajas, para tuercas prisioneras caracterizado porque incluye, por una parte, una matriz compuesta de dos medias placas presentando cada una un vaciado semicilíndrico en cuya superficie interna hay provistos un estrechamiento semi-anular y por lo menos, una escotadura apropiada para cooperar con un resalte correspondiente de la caja, estando montadas estas dos medias placas de forma que puedan ser separadas entre sí o ser llevadas a establecer contacto mutuo, constituyendo por tanto los dos vaciados reunidos una cavidad cilíndrica de revolución (prescindiendo de los estrechamientos y de las escotaduras ) u, por otra parte, un punzón cilíndrico de revolución cuya pared está provista de una nervadura anular sobresaliendo radialmente a un nivel axial correspondiente al de los estrechamientos de la matriz
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9899777A JPS5441387A (en) | 1977-08-18 | 1977-08-18 | Preparation of 3-(s)-1'phenylethylamino-proplyamino-bleomycin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES471297A1 true ES471297A1 (es) | 1979-01-16 |
Family
ID=14234606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES471297A Expired ES471297A1 (es) | 1977-08-18 | 1978-06-30 | Un procedimiento para la obtencion de 3-((s)-1'feniletilami-no) propilamino-bleomicina |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5441387A (es) |
| CS (1) | CS210673B2 (es) |
| DK (1) | DK148808C (es) |
| ES (1) | ES471297A1 (es) |
| HU (1) | HU179556B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54124692U (es) * | 1978-02-20 | 1979-08-31 | ||
| JPS62129961U (es) * | 1986-02-13 | 1987-08-17 | ||
| JPS62129960U (es) * | 1986-02-13 | 1987-08-17 | ||
| CN107434821A (zh) * | 2016-05-25 | 2017-12-05 | 国科戎安生物科技（北京）有限公司 | 一种111铟‑博来霉素衍生物的螯合物及应用 |
| CN107434822A (zh) * | 2016-05-25 | 2017-12-05 | 国科戎安生物科技（北京）有限公司 | 博来霉素衍生物及制备方法和应用 |
-
1977
- 1977-08-18 JP JP9899777A patent/JPS5441387A/ja active Granted
-
1978
- 1978-06-14 DK DK267478A patent/DK148808C/da not_active IP Right Cessation
- 1978-06-29 CS CS784304A patent/CS210673B2/cs unknown
- 1978-06-30 ES ES471297A patent/ES471297A1/es not_active Expired
- 1978-07-03 HU HU78NI217A patent/HU179556B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CS210673B2 (en) | 1982-01-29 |
| JPS5441387A (en) | 1979-04-02 |
| DK148808C (da) | 1986-04-14 |
| DK148808B (da) | 1985-10-07 |
| HU179556B (en) | 1982-11-29 |
| JPS5739752B2 (es) | 1982-08-23 |
| DK267478A (da) | 1979-02-19 |
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