ES471879A1 - Un procedimiento para la preparacion de una benzoilurea - Google Patents

Un procedimiento para la preparacion de una benzoilurea

Info

Publication number
ES471879A1
ES471879A1 ES471879A ES471879A ES471879A1 ES 471879 A1 ES471879 A1 ES 471879A1 ES 471879 A ES471879 A ES 471879A ES 471879 A ES471879 A ES 471879A ES 471879 A1 ES471879 A1 ES 471879A1
Authority
ES
Spain
Prior art keywords
benzoylureas
preparation
alkyllithium
insecticides
benzamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471879A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES471879A1 publication Critical patent/ES471879A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48—Y being a hydrogen or a carbon atom
    • C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Nuevo procedimiento para la preparación de benzoilureas. Los productos de este procedimiento son insecticidas. Se describe benzoilureas donde el nitrógeno N3 lleva un sustitúyete pirazina o benzopirazina. El procedimiento consiste en hacer reaccionar una benzamida, un alquil(C1-C7)litio, un cloroformiato de fenilo y una amina. En una realización de esta reacción, la benzamida se trata con el alquil-litio y un cloroformiato de fenilo en un disolvente inerte, a una temperatura comprendida entre -80 y -40ºC aproximadamente, para formar un uretano intermedio que se trata con una amina en un disolvente inerte, entre -80 a -40ºC aproximadamente y después se eleva lentamente la temperatura hasta unos 50-100ºC para obtener la benzoilurea deseada. En una segunda realización de la reacción, la benzamida se trata con el alquil-litio en un disolvente inerte, a una temperatura de -80 a -40ºC aproximadamente y la sal de litio así obtenida se trata después con un carbamato a una temperatura de -80 a -40ºC aproximadamente y se deja calentar la mezcla hasta unos 20-40ºC para obtener la benzoilurea deseada. El carbamato se obtiene por reacción de una amina con un cloroformiato de fenilo.
ES471879A 1977-07-27 1978-07-19 Un procedimiento para la preparacion de una benzoilurea Expired ES471879A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/819,639 US4133956A (en) 1977-07-27 1977-07-27 Preparation of benzoylureas

Publications (1)

Publication Number Publication Date
ES471879A1 true ES471879A1 (es) 1979-02-01

Family

ID=25228664

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471879A Expired ES471879A1 (es) 1977-07-27 1978-07-19 Un procedimiento para la preparacion de una benzoilurea

Country Status (10)

Country Link
US (1) US4133956A (es)
CA (1) CA1103251A (es)
CS (2) CS198106B2 (es)
ES (1) ES471879A1 (es)
HU (1) HU180726B (es)
IE (1) IE47001B1 (es)
IL (1) IL54928A (es)
NZ (1) NZ187621A (es)
PL (1) PL115711B1 (es)
SU (1) SU799662A3 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399152A (en) * 1980-04-03 1983-08-16 Duphar International B.V. Substituted benzoyl ureas as insecticides
US4425343A (en) 1980-10-24 1984-01-10 Nissan Chemical Industries, Ltd. Benzoazine ether or thioether linkage containing urea compounds, process for producing same and insecticides containing said compounds
US4405552A (en) * 1981-03-03 1983-09-20 Eli Lilly And Company 1-Benzoyl-3-(arylphyridyl)urea compounds
US4366155A (en) * 1981-03-30 1982-12-28 Eli Lilly And Company 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method
US5135953A (en) * 1984-12-28 1992-08-04 Ciba-Geigy Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals
AR029489A1 (es) * 2000-03-10 2003-07-02 Euro Celtique Sa Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento
US20040034225A1 (en) * 2000-05-17 2004-02-19 Jacqueline Marchand-Brynaert Aryl-substituted n, n-heterocyclic compounds, method for their preparationand their use in therapeutics and diagnostics
AR036873A1 (es) * 2001-09-07 2004-10-13 Euro Celtique Sa Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento
AR037233A1 (es) 2001-09-07 2004-11-03 Euro Celtique Sa Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL160809C (nl) * 1970-05-15 1979-12-17 Duphar Int Res Werkwijze ter bereiding van benzoylureumverbindingen, alsmede werkwijze ter bereiding van insekticide prepara- ten op basis van benzoylureumverbindingen.

Also Published As

Publication number Publication date
NZ187621A (en) 1980-11-28
IL54928A (en) 1982-02-28
CA1103251A (en) 1981-06-16
HU180726B (en) 1983-04-29
CS198106B2 (en) 1980-05-30
IE781242L (en) 1979-01-27
PL115711B1 (en) 1981-04-30
IE47001B1 (en) 1983-11-30
PL207831A1 (pl) 1979-11-19
SU799662A3 (ru) 1981-01-23
US4133956A (en) 1979-01-09
CS198105B2 (en) 1980-05-30

Similar Documents

Publication Publication Date Title
BG29121A3 (en) Herbicide means
PT64898A (en) N-(4-piperidinyl)-n-phenylamides and carbamates
GB1527562A (en) Substituted-methyl-11-cyano-9,10-dihydroethanoanthracene-11-carboxylates useful as intermediates
IT7849473A0 (it) Procedimento per preparare 1,2 polibutadiene
ES475379A1 (es) Procedimiento para la obtencion de 1,4-dihidropiridinas ni- tro-sustituidas
BG33006A3 (en) Method for obtaining of n- (perfluoracil)- n- phosphonomethyl- glycine compounds
ES451117A1 (es) Un procedimiento para preparar 3-piridil-isoxazolidinas.
EG12484A (en) Asymmerical bis,carbamate compounds used as insecticides and acaricides
IE781242L (en) Process for the preparation of benzoylureas.
ES471642A1 (es) Un procedimiento para preparar una nueva composicion insec- ticida
ES471849A1 (es) Un procedimiento para la preparacion de nuevos fenilacetatos
ES447320A1 (es) Procedimiento para preparar nuevos compuestos plaguicidas.
ES455409A1 (es) Un procedimiento para la preparacion de un compuesto de tia-diazolilbenzamida.
BG32412A3 (en) Akaracide means
ES459297A1 (es) Procedimiento para la preparacion de antraquinon-bis-amidi- nas.
ES443371A1 (es) Un procedimiento de preparacion de imidazolidinonas.
IL57464A (en) N-(phenylcarbamoyl)benzimidates,process for their preparation and insecticidal compositions containing them
GB2001053A (en) Insecticidal substituted benzoyl ureas
ES457744A1 (es) Un metodo para preparar compuestos de fluoruro de carbama- to-carbamoilo.
ES446666A1 (es) Un procedimiento para la preparacion de nuevos derivados de 5-fenil-2-furamidoxinicas.
AU519127B2 (en) N-(1, 3, 4-thiadiazol-2-7l) benzamides
SE7805994L (sv) Cyklopropansyraanilider, sett att framstella desamma och fungicida medel innehallande dessa foreningar
ES440233A1 (es) Procedimiento de preparacion de derivados carbamato.
AU525469B2 (en) Bis(o-imino-n-methyl-carsamic acid)-n, n 1-disulfide derivatives
GB1514036A (en) Process for the preparation of triazine-2,4-diones and their use as pesticides