ES472001A1 - Procedure for the preparation of 1,2-substitute 3-chianoguanidinas. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of 1,2-substitute 3-chianoguanidinas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES472001A1 ES472001A1 ES472001A ES472001A ES472001A1 ES 472001 A1 ES472001 A1 ES 472001A1 ES 472001 A ES472001 A ES 472001A ES 472001 A ES472001 A ES 472001A ES 472001 A1 ES472001 A1 ES 472001A1
- Authority
- ES
- Spain
- Prior art keywords
- translation
- procedure
- preparation
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- UJPVQNYPRMLGHM-UHFFFAOYSA-N 5-methyl-4-methylsulfanyl-1h-imidazole Chemical compound CSC=1NC=NC=1C UJPVQNYPRMLGHM-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 150000001718 carbodiimides Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- QGBSISYHAICWAH-UHFFFAOYSA-N dicyandiamide Chemical class NC(N)=NC#N QGBSISYHAICWAH-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- XDLNRRRJZOJTRW-UHFFFAOYSA-N thiohypochlorous acid Chemical compound ClS XDLNRRRJZOJTRW-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedure for the preparation of 1,2-substituted 3-cyano-guanidines, of the following general formula: ** (Formula) ** where R1 and R2 are groups selected from a low molecular weight alkyl, from one to six atoms of carbon, linear, branched, cyclic or an aromatic group, being able to support substituents selected from mercapto, chlorine, bromine or a botorocycle such as 5-methyl-4-methylthio-imidazole, characterized in that one of the equivalent of a carbodiimide is added to four equivalents of cyanamide to form an intermediate of the following general formula: R1-N = C = (+) NH-R2 * NC-NH (-) (II) where R1 and R2 have the significance given above, and that their solutions in a solvent from the group comprising acetonitrile, dimethylformamide, dimethylacetamide, dimethyl sulfoxide, 1,4-dioxane and their aqueous-organic mixtures, are heated at temperatures between 90 and 160ºC to obtain the compound of formula I. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES472001A ES472001A1 (en) | 1978-07-24 | 1978-07-24 | Procedure for the preparation of 1,2-substitute 3-chianoguanidinas. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES472001A ES472001A1 (en) | 1978-07-24 | 1978-07-24 | Procedure for the preparation of 1,2-substitute 3-chianoguanidinas. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES472001A1 true ES472001A1 (en) | 1979-07-16 |
Family
ID=8476529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES472001A Expired ES472001A1 (en) | 1978-07-24 | 1978-07-24 | Procedure for the preparation of 1,2-substitute 3-chianoguanidinas. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES472001A1 (en) |
-
1978
- 1978-07-24 ES ES472001A patent/ES472001A1/en not_active Expired
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