ES472645A1 - Procedimiento para la obtencion de alfa-halometil aminas - Google Patents

Procedimiento para la obtencion de alfa-halometil aminas

Info

Publication number
ES472645A1
ES472645A1 ES472645A ES472645A ES472645A1 ES 472645 A1 ES472645 A1 ES 472645A1 ES 472645 A ES472645 A ES 472645A ES 472645 A ES472645 A ES 472645A ES 472645 A1 ES472645 A1 ES 472645A1
Authority
ES
Spain
Prior art keywords
hydrogen
carbonyl
4alkyl
halomethyl
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472645A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of ES472645A1 publication Critical patent/ES472645A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la obtención de alfa-halometil aminas de la fórmula **(Fórmula)** en que Y es FCH2-, F2CH-, F3C-; R1 es hidrógeno, alquil-carbonilo, en que la mitad alquilo tiene de 1 a 4 átomos de carbono y es recta o ramificada, alcoxicarbonilo, en que la mitad alcoxi tiene de 1 a 4 átomos de carbono y es recta o ramificada o O=C-CH-R7-NH2, en que R7 es hidrógeno, un grupo alquilo inferior recto o ramificado de 1 a 4 átomos de carbono, bencilo o p-hidroxibencilo; cada uno de R3, R4, R5, R''4 y R6 tiene el significado definido en la tabla I, en que R8 es hidrógeno, un grupo alquilo recto o ramificado de 1 a 8 átomos de carbono, alquilcarbonilo, en que la mitad alquilo es recta o ramificada o tiene de 1 a 6 átomos de carbono, benzoilo o fenilalquilenocarbonilo, en que la mitad de alquileno es recta o ramificada y tiene de 1 a 6 átomos de carbono.
ES472645A 1977-09-01 1978-08-17 Procedimiento para la obtencion de alfa-halometil aminas Expired ES472645A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83004177A 1977-09-01 1977-09-01
US91782178A 1978-06-22 1978-06-22

Publications (1)

Publication Number Publication Date
ES472645A1 true ES472645A1 (es) 1979-10-16

Family

ID=27125317

Family Applications (1)

Application Number Title Priority Date Filing Date
ES472645A Expired ES472645A1 (es) 1977-09-01 1978-08-17 Procedimiento para la obtencion de alfa-halometil aminas

Country Status (11)

Country Link
JP (1) JPS5446727A (es)
AU (1) AU3872678A (es)
DE (1) DE2836674A1 (es)
DK (1) DK384878A (es)
ES (1) ES472645A1 (es)
FR (1) FR2401905A1 (es)
GB (1) GB2003871B (es)
IL (1) IL55456A0 (es)
IT (1) IT1106429B (es)
NL (1) NL7808937A (es)
SE (1) SE7809006L (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
JP5902575B2 (ja) * 2012-07-20 2016-04-13 国立大学法人お茶の水女子大学 光学活性含フッ素アミン化合物の製造方法並びに光学活性含フッ素アミン化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1324220A (fr) * 1960-11-05 1963-04-19 Science Nouvelles amines fluorées et trifluorométhylées et leurs procédés de préparation
GB1218135A (en) * 1967-07-28 1971-01-06 Abbott Lab Substituted phenethylamine derivatives
IE46910B1 (en) * 1977-06-01 1983-11-02 Merck & Co Inc Fluorinated alkylamines and process for preparing same
IE47542B1 (en) * 1977-06-01 1984-04-18 Merck & Co Inc Di-and tri-fluoromethyl amino acids and amines,compositions and processes for preparing said compounds

Also Published As

Publication number Publication date
DE2836674A1 (de) 1979-03-15
NL7808937A (nl) 1979-03-05
GB2003871B (en) 1982-05-06
FR2401905A1 (fr) 1979-03-30
IT7850878A0 (it) 1978-08-28
DK384878A (da) 1979-03-02
GB2003871A (en) 1979-03-21
IL55456A0 (en) 1978-10-31
SE7809006L (sv) 1979-03-02
IT1106429B (it) 1985-11-11
AU3872678A (en) 1980-02-14
JPS5446727A (en) 1979-04-12

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