ES473364A1 - 1-amino-alkyl-3,4-diphenyl-1hpyrazoles - Google Patents
1-amino-alkyl-3,4-diphenyl-1hpyrazolesInfo
- Publication number
- ES473364A1 ES473364A1 ES473364A ES473364A ES473364A1 ES 473364 A1 ES473364 A1 ES 473364A1 ES 473364 A ES473364 A ES 473364A ES 473364 A ES473364 A ES 473364A ES 473364 A1 ES473364 A1 ES 473364A1
- Authority
- ES
- Spain
- Prior art keywords
- diphenyl
- amino
- alkyl
- prepared
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 abstract 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1-(Lower aminoalkyl)-3,4-diphenyl-1H-pyrazoles are prepared by reducing a 1-(cyanoalkyl)-3,4-diphenyl-1H-pyrazole with hydrogen in the presence of aqueous ammonia, of methylamine, of dimethylamine or of diethylamine and of a catalyst the compounds are prepared in the form of the base or of an acid addition salt. They are antidepressant agents and analgesic agents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75231676A | 1976-12-20 | 1976-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES473364A1 true ES473364A1 (en) | 1979-04-16 |
Family
ID=25025781
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES465206A Expired ES465206A1 (en) | 1976-12-20 | 1977-12-19 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
| ES473367A Expired ES473367A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
| ES473376A Expired ES473376A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
| ES473364A Expired ES473364A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
| ES473365A Expired ES473365A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
| ES473366A Expired ES473366A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES465206A Expired ES465206A1 (en) | 1976-12-20 | 1977-12-19 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
| ES473367A Expired ES473367A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
| ES473376A Expired ES473376A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES473365A Expired ES473365A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
| ES473366A Expired ES473366A1 (en) | 1976-12-20 | 1978-09-14 | 1-amino-alkyl-3,4-diphenyl-1hpyrazoles |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPS5377059A (en) |
| AR (1) | AR214655A1 (en) |
| AT (2) | AT363071B (en) |
| AU (1) | AU511482B2 (en) |
| BE (1) | BE862038A (en) |
| CA (1) | CA1098527A (en) |
| CH (5) | CH626067A5 (en) |
| DE (1) | DE2756852A1 (en) |
| DK (1) | DK146624C (en) |
| ES (6) | ES465206A1 (en) |
| FI (1) | FI66353C (en) |
| FR (1) | FR2421887A1 (en) |
| GB (1) | GB1565319A (en) |
| HK (1) | HK36785A (en) |
| IE (1) | IE46612B1 (en) |
| IL (1) | IL53498A (en) |
| LU (1) | LU78723A1 (en) |
| MX (1) | MX4722E (en) |
| NL (2) | NL7713811A (en) |
| NO (1) | NO147108C (en) |
| NZ (1) | NZ185811A (en) |
| PH (1) | PH15728A (en) |
| PT (1) | PT67431B (en) |
| SE (1) | SE443560B (en) |
| ZA (1) | ZA777163B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965825A (en) | 1981-11-03 | 1990-10-23 | The Personalized Mass Media Corporation | Signal processing apparatus and methods |
| US7831204B1 (en) | 1981-11-03 | 2010-11-09 | Personalized Media Communications, Llc | Signal processing apparatus and methods |
| USRE47642E1 (en) | 1981-11-03 | 2019-10-08 | Personalized Media Communications LLC | Signal processing apparatus and methods |
| US4994482A (en) * | 1989-07-31 | 1991-02-19 | Bristol-Myers Squibb Company | Arylpyrazol derivatives as anti-platelet agents, compositions and use |
| FR2786188B1 (en) * | 1998-11-24 | 2002-10-31 | Hoechst Marion Roussel Inc | NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
-
1977
- 1977-11-28 CA CA291,869A patent/CA1098527A/en not_active Expired
- 1977-11-29 NZ NZ185811A patent/NZ185811A/en unknown
- 1977-11-29 IE IE2418/77A patent/IE46612B1/en unknown
- 1977-11-30 IL IL53498A patent/IL53498A/en unknown
- 1977-12-01 GB GB50129/77A patent/GB1565319A/en not_active Expired
- 1977-12-02 ZA ZA00777163A patent/ZA777163B/en unknown
- 1977-12-06 AU AU31262/77A patent/AU511482B2/en not_active Expired
- 1977-12-08 MX MX776675U patent/MX4722E/en unknown
- 1977-12-09 PH PH20537A patent/PH15728A/en unknown
- 1977-12-13 NL NL7713811A patent/NL7713811A/en not_active Application Discontinuation
- 1977-12-16 FR FR7738112A patent/FR2421887A1/en active Granted
- 1977-12-16 NO NO774338A patent/NO147108C/en unknown
- 1977-12-16 AT AT0902077A patent/AT363071B/en active
- 1977-12-19 DK DK566277A patent/DK146624C/en not_active IP Right Cessation
- 1977-12-19 ES ES465206A patent/ES465206A1/en not_active Expired
- 1977-12-19 FI FI773836A patent/FI66353C/en not_active IP Right Cessation
- 1977-12-19 SE SE7714461A patent/SE443560B/en not_active IP Right Cessation
- 1977-12-19 PT PT67431A patent/PT67431B/en unknown
- 1977-12-20 AR AR270427A patent/AR214655A1/en active
- 1977-12-20 CH CH1568677A patent/CH626067A5/en not_active IP Right Cessation
- 1977-12-20 LU LU78723A patent/LU78723A1/xx unknown
- 1977-12-20 BE BE1008592A patent/BE862038A/en not_active IP Right Cessation
- 1977-12-20 DE DE19772756852 patent/DE2756852A1/en active Granted
- 1977-12-20 JP JP15349777A patent/JPS5377059A/en active Granted
-
1978
- 1978-09-14 ES ES473367A patent/ES473367A1/en not_active Expired
- 1978-09-14 ES ES473376A patent/ES473376A1/en not_active Expired
- 1978-09-14 ES ES473364A patent/ES473364A1/en not_active Expired
- 1978-09-14 ES ES473365A patent/ES473365A1/en not_active Expired
- 1978-09-14 ES ES473366A patent/ES473366A1/en not_active Expired
-
1980
- 1980-06-06 AT AT0299780A patent/AT363074B/en not_active IP Right Cessation
-
1981
- 1981-04-08 CH CH237881A patent/CH627451A5/en not_active IP Right Cessation
- 1981-04-08 CH CH238081A patent/CH627171A5/en not_active IP Right Cessation
- 1981-04-08 CH CH237981A patent/CH627170A5/en not_active IP Right Cessation
- 1981-04-16 CH CH254481A patent/CH627172A5/en not_active IP Right Cessation
-
1985
- 1985-05-09 HK HK367/85A patent/HK36785A/en unknown
-
1990
- 1990-10-09 NL NL9002188A patent/NL9002188A/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971103 |