ES473484A1 - A procedure for the preparation of new eteres of the clavulan acid (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of new eteres of the clavulan acid (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES473484A1 ES473484A1 ES473484A ES473484A ES473484A1 ES 473484 A1 ES473484 A1 ES 473484A1 ES 473484 A ES473484 A ES 473484A ES 473484 A ES473484 A ES 473484A ES 473484 A1 ES473484 A1 ES 473484A1
- Authority
- ES
- Spain
- Prior art keywords
- translation
- preparation
- new
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 3
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 abstract 2
- 229960003324 clavulanic acid Drugs 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 abstract 1
- -1 clavulanic acid ethers Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
A process for the preparation of new clavulanic acid ethers of formula (I) ** formula ** or a salt or ester thereof where R1 is a hydrogen atom or a lower alkyl, aryl or aralkyl group, R2 and R3 are independently hydrogen or a lower alkyl, aryl or aralkyl group R2 and R3 are independently hydrogen, aryl, aralkyl, lower alkyl or substituted alkyl, or R3 binds to R1 to form a 4, 5 or 6-membered ring or binds to R2 to forming a 5- or 6-membered ring, the process of which comprises a) reacting an ester of clavulanic acid with a compound of the formula (XV) Y-CHR1-NR-CO-R3 where R1, R2 and R3 are those defined with relative to formula (I) and Y is a movable group, b) optionally converting the ester thus formed into the free acid or salt thereof (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3904077 | 1977-09-20 | ||
| GB3925177 | 1977-09-21 | ||
| GB7826989 | 1978-06-15 | ||
| GB7827497 | 1978-06-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES473484A1 true ES473484A1 (en) | 1979-11-01 |
Family
ID=27448931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES473484A Expired ES473484A1 (en) | 1977-09-20 | 1978-09-19 | A procedure for the preparation of new eteres of the clavulan acid (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES473484A1 (en) |
-
1978
- 1978-09-19 ES ES473484A patent/ES473484A1/en not_active Expired
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