ES473706A1 - Procedimiento para la obtencion de derivados de adamantila- mina - Google Patents

Procedimiento para la obtencion de derivados de adamantila- mina

Info

Publication number
ES473706A1
ES473706A1 ES473706A ES473706A ES473706A1 ES 473706 A1 ES473706 A1 ES 473706A1 ES 473706 A ES473706 A ES 473706A ES 473706 A ES473706 A ES 473706A ES 473706 A1 ES473706 A1 ES 473706A1
Authority
ES
Spain
Prior art keywords
derivatives
procedure
obtaining
formula
adamantila
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES473706A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES473706A1 publication Critical patent/ES473706A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1.Procedimiento para la obtención de derivados de adamantilamina de fórmula I, **(Fórmula-01)** en donde R1 es alquilo (C1-5), R2 es alquilo (C1-5), y cada una de R4 y R5 es hidrógeno, ó R4 y R5, juntas, son un enlace, caracterizado porque se reduce un compuesto de fórmula IV, **(Fórmula-02)** en donde R2, R4 y R5 tienen los significados previamente indicados, y R7 es hidrógeno o alquilo de 1 a 4 átomos de carbono, convenientemente usando un complejo de aluminio, convenientemente en un disolvente aprótico, tal como tetrahidrofurano, a una temperatura comprendida entre 0ºC y 100ºC.
ES473706A 1976-12-16 1978-09-27 Procedimiento para la obtencion de derivados de adamantila- mina Expired ES473706A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1582076 1976-12-16

Publications (1)

Publication Number Publication Date
ES473706A1 true ES473706A1 (es) 1980-05-16

Family

ID=4412220

Family Applications (2)

Application Number Title Priority Date Filing Date
ES465044A Expired ES465044A1 (es) 1976-12-16 1977-12-14 Procedimiento para la obtencion de derivados de la adamanti-lamina
ES473706A Expired ES473706A1 (es) 1976-12-16 1978-09-27 Procedimiento para la obtencion de derivados de adamantila- mina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES465044A Expired ES465044A1 (es) 1976-12-16 1977-12-14 Procedimiento para la obtencion de derivados de la adamanti-lamina

Country Status (17)

Country Link
US (1) US4146626A (es)
JP (1) JPS5377099A (es)
AU (1) AU3156777A (es)
BE (1) BE861854A (es)
DE (1) DE2753947A1 (es)
DK (1) DK545277A (es)
ES (2) ES465044A1 (es)
FI (1) FI773688A7 (es)
FR (1) FR2374323A1 (es)
IL (1) IL53609A0 (es)
IT (1) IT1092239B (es)
NL (1) NL7713719A (es)
NZ (1) NZ185966A (es)
PH (1) PH13411A (es)
PT (1) PT67407B (es)
SE (1) SE7713862L (es)
ZA (1) ZA777491B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6166165A (en) * 1996-12-18 2000-12-26 Witco Corporation Polyurethane synthesis from functional group terminated polymers containing sulfonate groups

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3228942A (en) * 1966-01-11 Methyl and i,g-dimeti-iyl ergoline i compounds
GB985004A (en) * 1962-06-18 1965-03-03 Farmaceutici Italia 6-methyl-ergoline i derivatives

Also Published As

Publication number Publication date
US4146626A (en) 1979-03-27
ZA777491B (en) 1979-07-25
PH13411A (en) 1980-03-28
ES465044A1 (es) 1979-01-01
SE7713862L (sv) 1978-06-17
FR2374323A1 (fr) 1978-07-13
DK545277A (da) 1978-06-17
BE861854A (fr) 1978-06-14
NZ185966A (en) 1980-05-08
PT67407B (fr) 1979-09-20
IL53609A0 (en) 1978-03-10
PT67407A (fr) 1978-01-01
FI773688A7 (fi) 1978-06-17
AU3156777A (en) 1979-06-21
IT1092239B (it) 1985-07-06
DE2753947A1 (de) 1978-06-29
JPS5377099A (en) 1978-07-08
NL7713719A (nl) 1978-06-20

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