ES476449A1 - Procedimiento de preparacion de derivados de piridazinona. - Google Patents

Procedimiento de preparacion de derivados de piridazinona.

Info

Publication number
ES476449A1
ES476449A1 ES476449A ES476449A ES476449A1 ES 476449 A1 ES476449 A1 ES 476449A1 ES 476449 A ES476449 A ES 476449A ES 476449 A ES476449 A ES 476449A ES 476449 A1 ES476449 A1 ES 476449A1
Authority
ES
Spain
Prior art keywords
carbon atoms
anorexigenic
group containing
pyridazinones
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES476449A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Albert Rolland SA
Original Assignee
Laboratoires Albert Rolland SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Albert Rolland SA filed Critical Laboratoires Albert Rolland SA
Publication of ES476449A1 publication Critical patent/ES476449A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/12—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C07D237/16—Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento de preparación de derivados de piridazinona de la fórmula I **fórmula** en la cual R1 y R2, idénticos o diferentes, representan el átomo de hidrógeno , un átomo de halógeno, un grupo alcohilo de 1 a 3 átomos de carbono, un grupo alcoxi de 1 a 3 átomos de carbono o un grupo trifluorometilo, y R3 representa un grupo alcohilo de 1 a 4 átomos de carbono mono o polihidroxilado, pudiendo estas funciones alcoholes estar esterificadas por un ácido benzoico, sustituido o no, procedimiento caracterizado porque en medio básico se hace reaccionar un fenol de fórmula **fórmula** con un compuesto de la fórmula ** fórmula**, fórmulas en las cuales R1, R2, y R3 tienen el mismo significado que se ha definido antes.
ES476449A 1977-04-28 1978-11-20 Procedimiento de preparacion de derivados de piridazinona. Expired ES476449A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7712888A FR2388799A1 (fr) 1977-04-28 1977-04-28 Derives de pyridazinone, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES476449A1 true ES476449A1 (es) 1979-05-16

Family

ID=9190051

Family Applications (2)

Application Number Title Priority Date Filing Date
ES469234A Expired ES469234A1 (es) 1977-04-28 1978-04-27 Procedimiento de preparacion de derivados de piridazinona
ES476449A Expired ES476449A1 (es) 1977-04-28 1978-11-20 Procedimiento de preparacion de derivados de piridazinona.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES469234A Expired ES469234A1 (es) 1977-04-28 1978-04-27 Procedimiento de preparacion de derivados de piridazinona

Country Status (18)

Country Link
US (1) US4188388A (es)
JP (1) JPS53135993A (es)
AU (1) AU3552678A (es)
BE (1) BE866492A (es)
DD (1) DD135488A5 (es)
DE (1) DE2817649A1 (es)
ES (2) ES469234A1 (es)
FR (1) FR2388799A1 (es)
GB (1) GB1584119A (es)
IE (1) IE46730B1 (es)
IL (1) IL54547A0 (es)
IT (1) IT1111174B (es)
LU (1) LU79520A1 (es)
NL (1) NL7804374A (es)
NZ (1) NZ187085A (es)
PL (1) PL112610B1 (es)
PT (1) PT67958B (es)
ZA (1) ZA782209B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
US8076334B2 (en) * 2007-09-20 2011-12-13 Hoffmann-La Roche Inc. Prodrugs of thyroid hormone analogs
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
PL227639B1 (pl) 2014-05-28 2018-01-31 Werner Kenkel Spolka Z Ograniczona Odpowiedzialnoscia Platforma ekspozycyjna

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1913265A1 (de) * 1969-03-15 1970-10-01 Basf Ag Verfahren zur Herstellung von 2-Alkylpyridazoniumverbindungen

Also Published As

Publication number Publication date
IT1111174B (it) 1986-01-13
BE866492A (fr) 1978-10-27
PT67958A (fr) 1978-05-01
US4188388A (en) 1980-02-12
AU3552678A (en) 1979-11-01
IL54547A0 (en) 1978-07-31
ES469234A1 (es) 1980-05-16
LU79520A1 (fr) 1978-11-28
NZ187085A (en) 1979-12-11
JPS53135993A (en) 1978-11-28
PL206456A1 (pl) 1979-04-23
PL112610B1 (en) 1980-10-31
PT67958B (fr) 1979-11-14
IE780778L (en) 1978-10-28
NL7804374A (nl) 1978-10-31
IT7822754A0 (it) 1978-04-27
FR2388799A1 (fr) 1978-11-24
DD135488A5 (de) 1979-05-09
FR2388799B1 (es) 1980-06-27
DE2817649A1 (de) 1978-11-09
GB1584119A (en) 1981-02-04
ZA782209B (en) 1979-04-25
IE46730B1 (en) 1983-09-07

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