ES478416A1 - Un procedimiento para la preparacion de un derivado de flio-xal-2-oxima. - Google Patents

Un procedimiento para la preparacion de un derivado de flio-xal-2-oxima.

Info

Publication number
ES478416A1
ES478416A1 ES478416A ES478416A ES478416A1 ES 478416 A1 ES478416 A1 ES 478416A1 ES 478416 A ES478416 A ES 478416A ES 478416 A ES478416 A ES 478416A ES 478416 A1 ES478416 A1 ES 478416A1
Authority
ES
Spain
Prior art keywords
glyoxal
derivatives
relieving pain
oxim
inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES478416A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of ES478416A1 publication Critical patent/ES478416A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Esta invención proporciona nuevos derivados de glioxal-2-oxima representados por la fórmula química **fórmula** donde R es hidrógeno o un grupo alquilo inferior o fenilo, Estos derivados se preparan por reacción del correspondiente isoxazol-5-carbaldehido con nitrometano, en presencia de un alcóxido metálico, o del correspondiente 5-acetilisoxazol con un nitrito. Ejercen actividad anti-inflamatoria y/o analgésica.
ES478416A 1978-03-09 1979-03-08 Un procedimiento para la preparacion de un derivado de flio-xal-2-oxima. Expired ES478416A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53027300A JPS6034546B2 (ja) 1978-03-09 1978-03-09 グリオキサ−ル−２−オキシム誘導体及びその製造方法

Publications (1)

Publication Number Publication Date
ES478416A1 true ES478416A1 (es) 1979-12-16

Family

ID=12217231

Family Applications (2)

Application Number Title Priority Date Filing Date
ES478416A Expired ES478416A1 (es) 1978-03-09 1979-03-08 Un procedimiento para la preparacion de un derivado de flio-xal-2-oxima.
ES484056A Expired ES484056A1 (es) 1978-03-09 1979-09-10 Un procedimiento para la preparacion de un derivado de glio-xal-2-oxima

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES484056A Expired ES484056A1 (es) 1978-03-09 1979-09-10 Un procedimiento para la preparacion de un derivado de glio-xal-2-oxima

Country Status (7)

Country Link
US (3) US4212874A (es)
JP (1) JPS6034546B2 (es)
DE (1) DE2909025A1 (es)
ES (2) ES478416A1 (es)
FR (1) FR2419289A1 (es)
GB (1) GB2017091B (es)
IT (1) IT1114569B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3528753A1 (de) * 1985-08-10 1987-02-19 Bayer Ag Substituierte pyrazolin-5-one
DE3726127A1 (de) * 1987-08-06 1989-02-16 Basf Ag 5-formylisoxazole
DE3738909A1 (de) * 1987-11-17 1989-05-24 Basf Ag Verfahren zur herstellung von heterocyclisch-aromatischen aldehyden
US5360811A (en) * 1990-03-13 1994-11-01 Hoechst-Roussel Pharmaceuticals Incorporated 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents
US7229359B2 (en) * 2003-10-24 2007-06-12 Henry, Schooley & Associates, L.L.C. Continuous water ride
US7785207B2 (en) * 2005-04-20 2010-08-31 Water Ride Concepts, Inc. Water amusement system with elevated structure

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2772280A (en) * 1954-12-23 1956-11-27 Merck & Co Inc Synthesis of 4-amino-3-isoxazolidone and its derivatives
SE307356B (es) * 1963-07-31 1969-01-07 Shionogi & Co
GB1101158A (en) * 1964-11-20 1968-01-31 Shionogi & Co Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivatives
GB1164510A (en) * 1967-06-15 1969-09-17 Ici Ltd Novel Isoxazole Derivatives, the preparation thereof, and Compositions containing the same
FR2073284B1 (es) * 1969-12-23 1973-07-13 Ferlux
JPS5229311B2 (es) * 1972-08-22 1977-08-01

Also Published As

Publication number Publication date
FR2419289B1 (es) 1982-10-08
US4243812A (en) 1981-01-06
ES484056A1 (es) 1980-04-16
IT1114569B (it) 1986-01-27
US4224450A (en) 1980-09-23
DE2909025A1 (de) 1979-09-13
GB2017091B (en) 1982-09-02
IT7948245A0 (it) 1979-03-07
GB2017091A (en) 1979-10-03
JPS6034546B2 (ja) 1985-08-09
FR2419289A1 (fr) 1979-10-05
JPS54119457A (en) 1979-09-17
US4212874A (en) 1980-07-15

Similar Documents

Publication Publication Date Title
ES8400737A1 (es) "un procedimiento para preparar derivados de nicotinamida".
ES483700A1 (es) Un procedimiento para preparar 2-nitroimidazols.
GB1495348A (en) Haloacetanilides as fungicidally active substances
ES484056A1 (es) Un procedimiento para la preparacion de un derivado de glio-xal-2-oxima
ES8506575A1 (es) Procedimiento para la preparacion de nuevos derivados de acidos fenilalcanoicos.
ES489823A1 (es) Procedimiento para la obtencion de un catalizador para la polimerizacion de butadieno
ES436715A1 (es) Metodo para la preparacion de un nuevo compuesto herbicida.
JPS57203068A (en) Novel 1-phenylisoquinoline derivative
ES480827A1 (es) Procedimiento para la preparacion de acidos fenilaminotiofe-noaceticos.
ES8707530A1 (es) Un procedimiento para la preparacion de una octahidroindolizina
IE780126L (en) Thiazoloisoquinoline derivatives
ES478706A1 (es) Un metodo para producir un compuesto desmetilmaitansinoide.
JPS57171972A (en) Manufacture of quinoline-4-ones
ES472467A1 (es) Un procedimiento para la preparacion de furanonas
JPS57165334A (en) Halogenobenzene derivative having optical active 2- methylbutyloxyphenyl group
ES481264A1 (es) Procedimiento para fabricar derivados del acido arilacetico.
ES427115A1 (es) Procedimiento de preparacion de nuevos derivados del acido acetico.
DE3164005D1 (en) Use of alpha-azolylglycoles as plant growth regulators
ES449068A1 (es) Procedimiento para preparar derivados de isoxazol.
ES482949A1 (es) Un procedimiento para la preparacion de compuestos derivadosde piridoxina
ATE32216T1 (de) Diphenylmethylimin-derivate.
ES8105982A1 (es) Procedimiento de preparacion del carbanion de la papaverina
ES8105250A1 (es) Un procedimiento para la preparacion de decalinas sustitui- das.
JPS5559135A (en) Production of alpha, alpha, alpha-trifluoro-o-toluic fluoride
ATE15184T1 (de) Fluorphenoxybenzylester, ihre herstellung und ihre verwendung als schaedlingsbekaempfungsmittel.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519