ES478672A1 - New synthesis procedure for N-2- (p-chlorophenoxy) -isobutiril-n'-morpholinometilurea. (Machine-translation by Google Translate, not legally binding) - Google Patents
New synthesis procedure for N-2- (p-chlorophenoxy) -isobutiril-n'-morpholinometilurea. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES478672A1 ES478672A1 ES478672A ES478672A ES478672A1 ES 478672 A1 ES478672 A1 ES 478672A1 ES 478672 A ES478672 A ES 478672A ES 478672 A ES478672 A ES 478672A ES 478672 A1 ES478672 A1 ES 478672A1
- Authority
- ES
- Spain
- Prior art keywords
- chlorophenoxy
- translation
- product
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 p-chlorophenoxy Chemical group 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 239000000047 product Substances 0.000 abstract 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 239000002609 medium Substances 0.000 abstract 3
- 238000000746 purification Methods 0.000 abstract 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 239000006227 byproduct Substances 0.000 abstract 2
- 238000006683 Mannich reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- DDDQVDIPBFGVIG-UHFFFAOYSA-N plafibride Chemical compound C1COCCN1CNC(=O)NC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 DDDQVDIPBFGVIG-UHFFFAOYSA-N 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Obtaining the N-2 (p-chlorophenoxy) isobutyryl-n "-morpholinomethylurea (I), that is the product ita-104, according to the known procedure discussed, in the second step mentioned, which is that of the reaction of mannich, the following molecular species react: np-chlorophenoxy-isobutyrylurea, morpholine and formaldehyde and as mentioned above, in addition to the desired product (I), numerous undesired byproducts are produced. Then it is forced to proceed to a purification, which is carried out in aqueous medium. According to this purification, the product (I) obtained in the mannich reaction together with the other by-products is solubilized in aqueous medium, followed by precipitation in an alkaline medium. The drawback is noted that, because N-2- (p-chlorophenoxy) -isobutyryl-n "-morpholinomethylurea is unstable in an acid medium and also in an alkaline medium, the purification described is not very effective since it simultaneously it produces the degradation of the product. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES478672A ES478672A1 (en) | 1979-03-15 | 1979-03-15 | New synthesis procedure for N-2- (p-chlorophenoxy) -isobutiril-n'-morpholinometilurea. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES478672A ES478672A1 (en) | 1979-03-15 | 1979-03-15 | New synthesis procedure for N-2- (p-chlorophenoxy) -isobutiril-n'-morpholinometilurea. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES478672A1 true ES478672A1 (en) | 1979-06-01 |
Family
ID=8477854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478672A Expired ES478672A1 (en) | 1979-03-15 | 1979-03-15 | New synthesis procedure for N-2- (p-chlorophenoxy) -isobutiril-n'-morpholinometilurea. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES478672A1 (en) |
-
1979
- 1979-03-15 ES ES478672A patent/ES478672A1/en not_active Expired
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