ES479636A1 - Procedimiento para la obtencion de un antibiotico de efecto sinergistico. - Google Patents
Procedimiento para la obtencion de un antibiotico de efecto sinergistico.Info
- Publication number
- ES479636A1 ES479636A1 ES479636A ES479636A ES479636A1 ES 479636 A1 ES479636 A1 ES 479636A1 ES 479636 A ES479636 A ES 479636A ES 479636 A ES479636 A ES 479636A ES 479636 A1 ES479636 A1 ES 479636A1
- Authority
- ES
- Spain
- Prior art keywords
- antibiotics
- production
- synergistic mixtures
- mixtures
- antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000002195 synergetic effect Effects 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 abstract 2
- REACMANCWHKJSM-DWBVFMGKSA-M Cefsulodin sodium Chemical compound [Na+].C1=CC(C(=O)N)=CC=[N+]1CC1=C(C([O-])=O)N2C(=O)[C@@H](NC(=O)[C@@H](C=3C=CC=CC=3)S([O-])(=O)=O)[C@H]2SC1 REACMANCWHKJSM-DWBVFMGKSA-M 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- 229940126575 aminoglycoside Drugs 0.000 abstract 1
- 239000003781 beta lactamase inhibitor Substances 0.000 abstract 1
- 229940126813 beta-lactamase inhibitor Drugs 0.000 abstract 1
- 229960001281 cefsulodin sodium Drugs 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la obtención de un antibiótico de efecto sinergístico, caracterizado porque cefsulodin-sodio y un segundo antibiótico de unos de los grupos de los inhibidores de las beta-lactamasas, , penicilinas, cefalosporinas y aminoglicósidos se hacen inter-accionar sinergisticamente junto con excipiente farmacéutico en forma homogénea.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH419478 | 1978-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES479636A1 true ES479636A1 (es) | 1980-01-16 |
Family
ID=4271539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES479636A Expired ES479636A1 (es) | 1978-04-19 | 1979-04-17 | Procedimiento para la obtencion de un antibiotico de efecto sinergistico. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4263280A (es) |
| EP (1) | EP0004925B1 (es) |
| JP (1) | JPS54145221A (es) |
| AU (1) | AU523468B2 (es) |
| CA (1) | CA1134269A (es) |
| DE (1) | DE2962171D1 (es) |
| ES (1) | ES479636A1 (es) |
| IL (1) | IL57086A (es) |
| NZ (1) | NZ190218A (es) |
| PH (1) | PH16771A (es) |
| ZA (1) | ZA791822B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58198416A (ja) * | 1982-05-15 | 1983-11-18 | Ota Seiyaku Kk | セフアレキシンドライシロツプ剤の製造法 |
| EP0134302B1 (en) * | 1983-09-15 | 1987-06-16 | Bristol-Myers Company | Pharmaceutical compositions for treating resistant bacteria including anaerobes |
| JPS6143116A (ja) * | 1984-08-03 | 1986-03-01 | Shionogi & Co Ltd | 細菌性感染症の治療および治療薬 |
| AT392903B (de) * | 1987-10-08 | 1991-07-10 | Hoechst Ag | Pharmazeutische zubereitung enthaltend ein cephalosporin und ein penemantibiotikum |
| HUT57219A (en) * | 1989-09-04 | 1991-11-28 | Beecham Group Plc | Process for producing new beta-lactame compounds |
| US6063590A (en) * | 1991-11-18 | 2000-05-16 | The United States Of America As Represented By The Administrator Of The U.S. Environmental Protection Agency | Membrane filter agar medium containing two enzyme substrates used for the simultaneous detection of total coliforms and E. coli. |
| US6306621B1 (en) * | 1991-11-18 | 2001-10-23 | The United States Of America As Represented By The Administrator Of The U.S. Environmental Protection Agency | Membrane filter agar medium for simultaneous detection of total coliforms and E. coli |
| MX2007007235A (es) * | 2004-12-17 | 2007-10-19 | Venus Remedies Ltd | Combinacion de antibioticos para proporcionar una solucion total al tratamiento de infecciones. |
| US20060222716A1 (en) * | 2005-04-01 | 2006-10-05 | Joseph Schwarz | Colloidal solid lipid vehicle for pharmaceutical use |
| CN102367258A (zh) * | 2010-10-26 | 2012-03-07 | 海南美好西林生物制药有限公司 | 一种美洛西林钠的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1310642A (en) * | 1970-11-09 | 1973-03-21 | Pfizer | Alpha-sulfo-and alpha-sulfoalkylacylcephalosporins |
| BE786271A (fr) * | 1971-07-17 | 1973-01-15 | Takeda Chemical Industries Ltd | Cephalosporines |
-
1979
- 1979-04-06 PH PH22386A patent/PH16771A/en unknown
- 1979-04-09 US US06/028,032 patent/US4263280A/en not_active Expired - Lifetime
- 1979-04-09 DE DE7979101080T patent/DE2962171D1/de not_active Expired
- 1979-04-09 EP EP79101080A patent/EP0004925B1/de not_active Expired
- 1979-04-12 AU AU46067/79A patent/AU523468B2/en not_active Ceased
- 1979-04-17 CA CA325,609A patent/CA1134269A/en not_active Expired
- 1979-04-17 IL IL57086A patent/IL57086A/xx unknown
- 1979-04-17 ES ES479636A patent/ES479636A1/es not_active Expired
- 1979-04-18 ZA ZA791822A patent/ZA791822B/xx unknown
- 1979-04-18 NZ NZ190218A patent/NZ190218A/xx unknown
- 1979-04-19 JP JP4733779A patent/JPS54145221A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS54145221A (en) | 1979-11-13 |
| EP0004925B1 (de) | 1982-02-24 |
| EP0004925A1 (de) | 1979-10-31 |
| IL57086A (en) | 1982-09-30 |
| CA1134269A (en) | 1982-10-26 |
| DE2962171D1 (en) | 1982-03-25 |
| AU523468B2 (en) | 1982-07-29 |
| IL57086A0 (en) | 1979-07-25 |
| NZ190218A (en) | 1982-03-23 |
| US4263280A (en) | 1981-04-21 |
| ZA791822B (en) | 1980-04-30 |
| PH16771A (en) | 1984-02-22 |
| AU4606779A (en) | 1979-10-25 |
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