Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD International Holdings GmbH
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA00786054Aexternal-prioritypatent/ZA786054B/en
Application filed by Scherico LtdfiledCriticalScherico Ltd
Publication of ES480141A1publicationCriticalpatent/ES480141A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur
(AREA)
Abstract
Process for the preparation of 6-oxygenated-3, 20-dioxio-pregnane derivatives of the general formula i: ** (formula-01) ** where d ** (formula-02) **, a is hydrogen or, provided that y is (h, beta, oh), a can be chlorine, fluorine or methyl; b is hydrogen, or together with q, is a 14 alpha, 17 alpha-alkylidenedioxy group; x is hydrogen, fluorine or chlorine, y is oxygen, (h, beta oh) or (h, beta ocoh), or whenever x is chlorine, and can be (h, beta-chlorine) or (h, beta-fluorine) ); z is hydrocarbon carbonyl, alkoxycarbonyl, thioalkoxycarbonyl, or thioalkoxythiocarbonyl wherein z has up to 12 carbon atoms; q is hydrogen provided that w is (h, lower alkyl); or ov wherein v is hydrogen or an acyl radical of a hydrocarbon carboxylic acid having up to 12 carbon atoms or of benzoic acid substituted by halogen or a methoxy or retinoic acid group. (Machine-translation by Google Translate, not legally binding)
ES480141A1978-10-261979-05-02
PROCEDURE FOR THE PREPARATION OF DERIVATIVES 6-OXYGENATES-3, 20-DIOXO-PREGNANE.
ExpiredES480141A1
(en)
Procedure for the preparation of N- (r-tetrahydrofurfuril) -noroximorphone and N- (s-tetrahydrofurfuril) -norosimorphone new. (Machine-translation by Google Translate, not legally binding)