ES480166A1 - Metodo para preparar nuevas 2-arilamino-hexahidropiridinas y 2-arilamino-imidazolidinas. - Google Patents

Metodo para preparar nuevas 2-arilamino-hexahidropiridinas y 2-arilamino-imidazolidinas.

Info

Publication number
ES480166A1
ES480166A1 ES480166A ES480166A ES480166A1 ES 480166 A1 ES480166 A1 ES 480166A1 ES 480166 A ES480166 A ES 480166A ES 480166 A ES480166 A ES 480166A ES 480166 A1 ES480166 A1 ES 480166A1
Authority
ES
Spain
Prior art keywords
groups
carbon atoms
alcohol
group
arylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480166A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Philips Gloeilampenfabrieken NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Gloeilampenfabrieken NV filed Critical Philips Gloeilampenfabrieken NV
Publication of ES480166A1 publication Critical patent/ES480166A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12—Nitrogen atoms not forming part of a nitro radical
    • C07D239/14—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un método para preparar nuevas 2-arilamino- hexahidropirimidinas y 2-arilamino-imidazolidinas, o sales o complejos de las mismas, caracterizado porque se prepara un compuesto de la fórmula general: **(Fórmula-01)** en la que n es 0 ó 1, R1 y R2 son iguales o diferentes y representan átomos de hidrógeno, grupos alcohilo, alcohiloxi o alcohiltio que tienen de 4 a 12 átomos de carbono, grupos cicloalcohilo que tienen de 3 a 7 átomos de carbono, grupos benciloxi-, benciltio-, fenoxi- ó feniltio opcionalmente sustituidos con halógeno ó alcohilo de C1-C4, grupos fenialcohilo que tienen de 7 a 11 átomos de carbono, de los cuales el grupo fenilo está sustituido opcionalmente con halógeno, dialcohilamino, o con alcohilo, alcoxi o alcohiltio, los cuales grupos alcohilo, alcoxi o alcohiltio tienen de 1 a 6 átomos de carbono y están opcionalmente halogenados, grupos furialcohilo ó tienialcohilo de los cuales los grupos alcohilo tienen de 1 a 4 átomos de carbono, grupos dialcohilamino de los cuales losgrupos alcohilo tienen cada uno de ellos de 2 a 6 átomos de carbono, o grupos alcoxicarbonilo que tienen de 4 a 12 átomos de carbono, o en la cual R1 y R2 representan juntos un grupo trimetileno, tetrametileno ó butadienileno, con la condición de que R1 y R2 no son ambos átomos de hidrógeno, R3, R4, R7 y R8 son iguales o diferentes y representan átomos de hidrógeno o grupos alcohilo que tienen de 1 a 4 átomos de carbono, y R5 y R6 son iguales o diferentes y representan átomos de hidrógeno ó grupos alcohilo que tienen de 1 a 4 átomos de carbono, haciendo reaccionar un compuesto de la fórmula general **(Fórmula-02)** en la que R1 y R2 tienen los significados indicados anteriormente e Y y Z pueden ser ambos átomos de halógeno o grupos alcohiltio, o bien, cuando Y es un grupo amino, Z es un grupo alcoxi o grupo alcohiltio, con un compuesto de la fórmula general **(Fórmula-03)** en la que n, R3, R4, R5, R6, R7 y R8 tienen los significados antes indicados, haciendo que se separen HY y HZ, después de lo cual se obtiene el compuesto final mediante una reacción de aislamiento.
ES480166A 1977-10-18 1979-05-02 Metodo para preparar nuevas 2-arilamino-hexahidropiridinas y 2-arilamino-imidazolidinas. Expired ES480166A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7711390A NL7711390A (nl) 1977-10-18 1977-10-18 Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen.

Publications (1)

Publication Number Publication Date
ES480166A1 true ES480166A1 (es) 1979-12-16

Family

ID=19829358

Family Applications (2)

Application Number Title Priority Date Filing Date
ES474227A Expired ES474227A1 (es) 1977-10-18 1978-10-16 Metodo para preparar nuevas 2-arilamino-hexahidropirimidinasy 2-arilamino-imidazolidinas
ES480166A Expired ES480166A1 (es) 1977-10-18 1979-05-02 Metodo para preparar nuevas 2-arilamino-hexahidropiridinas y 2-arilamino-imidazolidinas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES474227A Expired ES474227A1 (es) 1977-10-18 1978-10-16 Metodo para preparar nuevas 2-arilamino-hexahidropirimidinasy 2-arilamino-imidazolidinas

Country Status (21)

Country Link
US (2) US4374143A (es)
EP (1) EP0001663B1 (es)
JP (1) JPS5463080A (es)
AR (1) AR225601A1 (es)
AU (1) AU521181B2 (es)
CA (1) CA1106845A (es)
CS (2) CS208757B2 (es)
DD (2) DD139989A5 (es)
DE (1) DE2861822D1 (es)
DK (1) DK458178A (es)
EG (1) EG13497A (es)
ES (2) ES474227A1 (es)
HU (1) HU178690B (es)
IL (1) IL55728A (es)
IT (1) IT1099744B (es)
NL (1) NL7711390A (es)
NZ (1) NZ188660A (es)
PL (2) PL120588B1 (es)
SU (2) SU895289A3 (es)
TR (1) TR20567A (es)
ZA (1) ZA785278B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7711390A (nl) * 1977-10-18 1979-04-20 Philips Nv Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen.
US4321838A (en) * 1979-08-13 1982-03-30 Feldman Robert I Power coupling for a chain saw
DE2933930A1 (de) * 1979-08-22 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.
US4647557A (en) * 1982-12-28 1987-03-03 Gerard Moinet Novel heterocyclic derivatives bearing an amino radical, processes for their production and the pharmaceutical compositions containing them
GB8922750D0 (en) * 1989-10-10 1989-11-22 Dow Chemical Co Fungicidal compounds,their production and use
US5292743A (en) * 1989-10-10 1994-03-08 Dowelanco Fungicidal compositions, fungicidal compounds, their production and use
GB9016800D0 (en) * 1990-07-31 1990-09-12 Shell Int Research Tetrahydropyrimidine derivatives
US5866579A (en) * 1997-04-11 1999-02-02 Synaptic Pharmaceutical Corporation Imidazole and imidazoline derivatives and uses thereof
NZ331480A (en) * 1997-09-04 2000-02-28 F 2-(Arylphenyl)amino-imidazoline derivatives and pharmaceutical compositions
US6184242B1 (en) 1997-09-04 2001-02-06 Syntex Usa (Llc) 2-(substituted-phenyl)amino-imidazoline derivatives
JP2001354659A (ja) * 2000-06-13 2001-12-25 Kureha Chem Ind Co Ltd 新規ピラゾリン誘導体、その製造方法、及び有害生物防除剤
US6417186B1 (en) 2000-11-14 2002-07-09 Syntex (U.S.A.) Llc Substituted-phenyl ketone derivatives as IP antagonists
CA2522817A1 (en) * 2003-05-01 2004-11-11 F. Hoffmann-La Roche Ag Imidazolin-2-ylaminophenyl amides as ip antagonists
KR100768609B1 (ko) * 2003-07-09 2007-10-18 에프. 호프만-라 로슈 아게 티오페닐아미노이미다졸린
JP2007308392A (ja) * 2006-05-16 2007-11-29 Bayer Cropscience Ag 殺虫性ベンズアミジン類
WO2016043260A1 (ja) * 2014-09-19 2016-03-24 塩野義製薬株式会社 環状グアニジンまたはアミジン化合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2899434A (en) * 1959-08-11 Z-phenylamino-l
US2899426A (en) * 1959-08-11 Synthesis of l
FR1211341A (fr) * 1955-12-19 1960-03-15 A Wander Dr Procédé pour la préparation de 2-amino-imidazolines
US3202660A (en) * 1961-10-09 1965-08-24 Boehringer Sohn Ingelheim Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
BE632578A (es) * 1963-05-22
DE1670274A1 (de) * 1966-10-31 1970-07-16 Boehringer Sohn Ingelheim Neues Verfahren zur Herstellung von 2-Arylamino-1,3-diazacycloalkenen-(2)
US3882229A (en) * 1972-07-21 1975-05-06 Nordmark Werke Gmbh Composition and method for shrinking mucous membranes
DE2316377C3 (de) * 1973-04-02 1978-11-02 Lentia Gmbh, Chem. U. Pharm. Erzeugnisse - Industriebedarf, 8000 Muenchen Verfahren zur Herstellung von 2-Phenyl-amino-2-imidazolin-Derivaten und von deren Salzen
AT330769B (de) * 1974-04-05 1976-07-26 Chemie Linz Ag Verfahren zur herstellung von 2-arylamino- 2-imidazolin-derivaten und ihren salzen
DE2542702C2 (de) * 1975-09-25 1983-11-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Verfahren zur Herstellung von 1-Benzoyl-2-(2,6-dichlorphenylamino)-2-imidazolin
NL7711390A (nl) * 1977-10-18 1979-04-20 Philips Nv Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen.
US4262005A (en) * 1978-05-31 1981-04-14 The Boots Company Limited Compounds, compositions and methods for controlling pests
DE2933930A1 (de) * 1979-08-22 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.

Also Published As

Publication number Publication date
IT7828761A0 (it) 1978-10-13
SU895289A3 (ru) 1981-12-30
JPS5463080A (en) 1979-05-21
NL7711390A (nl) 1979-04-20
EG13497A (en) 1982-06-30
NZ188660A (en) 1980-03-05
IT1099744B (it) 1985-09-28
IL55728A (en) 1982-05-31
EP0001663A1 (en) 1979-05-02
DE2861822D1 (en) 1982-07-01
JPS6141353B2 (es) 1986-09-13
DK458178A (da) 1979-04-19
CS208758B2 (en) 1981-09-15
PL120588B1 (en) 1982-03-31
AU521181B2 (en) 1982-03-18
HU178690B (en) 1982-06-28
EP0001663B1 (en) 1982-05-12
AR225601A1 (es) 1982-04-15
PL216996A1 (es) 1980-07-14
TR20567A (tr) 1982-01-01
ES474227A1 (es) 1979-10-16
US4396617A (en) 1983-08-02
DD139989A5 (de) 1980-02-06
PL210324A1 (es) 1980-03-10
SU969160A3 (ru) 1982-10-23
DD147846A5 (de) 1981-04-22
ZA785278B (en) 1980-05-28
CS208757B2 (en) 1981-09-15
US4374143A (en) 1983-02-15
AU4075478A (en) 1980-04-24
IL55728A0 (en) 1978-12-17
CA1106845A (en) 1981-08-11

Similar Documents

Publication Publication Date Title
ES463200A1 (es) Un procedimiento para la preparacion de nuevos derivados de piridazinona.
ES399497A1 (es) Procedimiento para la obtencion de p-mentano - 3 - carbosa-midas n - sustituidas.
SE425503B (sv) Bindemedelskomposition innefattande ett salt av en tereftalamid som gelningsmedel
ES474029A1 (es) Un procedimiento para la preparacion de n-(2-cloro-4-piri- dil)-ureas
ES474227A1 (es) Metodo para preparar nuevas 2-arilamino-hexahidropirimidinasy 2-arilamino-imidazolidinas
SE7601143L (sv) Nytt oxadiazolinonderivat
MD422C2 (ro) Derivaţi ai azolului şi compuţi intermediari pentru producerea lor
ES387834A1 (es) Procedimiento para la preparacion de amidas de acido de vi-tamina a.
ES8105976A1 (es) Procedimiento para la preparacion de acilureas
ES436986A1 (es) Un procedimiento para la preparacion de nuevos derivados de aminoacido.
ES415021A1 (es) Un procedimiento para la preparacion de compuestos de tria-zina.
ES8203350A1 (es) Procedimiento para la fabricacion de derivados del pirazol
ATE69448T1 (de) Chinolincarbonsaeure-derivate, diese enthaltende zusammensetzung, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von medikamenten.
ES418827A1 (es) Un procedimiento para preparar nuevos derivados 2-aminoinda-no.
ES388918A1 (es) Procedimiento para preparar amidas del acido 2-cloroetano- (tiono)-fosfonico.
ES421182A1 (es) Procedimiento para preparar 1-fenoxi-3-fenoxi-etilamino-2- propanoles.
ES444618A1 (es) Un procedimiento de preparacion de compuestos tiofenicos fosforilados.
ES439058A1 (es) Procedimiento para la preparacion de uretanos aromaticos.
ES432006A1 (es) Procedimiento para preparar esteres de acidos o-fenil-tio- notiolfosforicos.
DE68926016D1 (de) Halogeno-4-Methylpyrazole und Verfahren zu ihrer Herstellung
ES409552A1 (es) Un procedimiento para la preparacion de nuevos alcanosulfo-natos sustituidos.
ES483796A1 (es) Un procedimiento para la preparacion de derivados del acido-penam-3-carboxilico.
ES399859A1 (es) Procedimiento para la preparacion de formamidinas.
ES435365A1 (es) Procedimiento para la preparacion de derivados del 1,2- diaril-etileno.
ES393340A1 (es) Procedimiento para la preparacion de derivados de bornanami-na.