ES482986A1 - Un procedimiento para la produccion de derivados sililados- de penicilina. - Google Patents

Un procedimiento para la produccion de derivados sililados- de penicilina.

Info

Publication number: ES482986A1
Authority: ES; Spain
Prior art keywords: penicillins; production; acid chloride; anhydrous; acid
Prior art date: 1978-12-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES482986A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Co

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-18

Filing date

1979-07-30

Publication date

1980-09-01

1979-03-19 Priority claimed from US06/021,852 external-priority patent/US4240960A/en

1979-07-30 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1980-09-01 Publication of ES482986A1 publication Critical patent/ES482986A1/es

Status Expired legal-status Critical Current

Links

229930182555 Penicillin Natural products 0.000 title abstract 2
150000002960 penicillins Chemical class 0.000 title abstract 2
NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 2
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
230000010933 acylation Effects 0.000 abstract 1
238000005917 acylation reaction Methods 0.000 abstract 1
LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 abstract 1
229960003022 amoxicillin Drugs 0.000 abstract 1
AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 abstract 1
229960000723 ampicillin Drugs 0.000 abstract 1
230000005587 bubbling Effects 0.000 abstract 1
229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
239000001569 carbon dioxide Substances 0.000 abstract 1
-1 e.g. Natural products 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 abstract 1
125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)

ES482986A 1978-12-18 1979-07-30 Un procedimiento para la produccion de derivados sililados- de penicilina. Expired ES482986A1 (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US97070478A	1978-12-18	1978-12-18
US478079A	1979-01-19	1979-01-19
US06/021,852 US4240960A (en)	1979-03-19	1979-03-19	Trimethylsilyl substituted penicillins

Publications (1)

Publication Number	Publication Date
ES482986A1 true ES482986A1 (es)	1980-09-01

Family

ID=27357705

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES482986A Expired ES482986A1 (es)	1978-12-18	1979-07-30	Un procedimiento para la produccion de derivados sililados- de penicilina.
ES490644A Expired ES8104301A1 (es)	1978-12-18	1980-04-16	Mejoras introducidas en un procedimiento para la produccion de una penicilina

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES490644A Expired ES8104301A1 (es)	1978-12-18	1980-04-16	Mejoras introducidas en un procedimiento para la produccion de una penicilina

Country Status (20)

Country	Link
AR (1)	AR225898A1 (da)
AT (1)	AT364849B (da)
AU (1)	AU531779B2 (da)
CA (1)	CA1141752A (da)
CH (1)	CH642972A5 (da)
DK (2)	DK160613C (da)
ES (2)	ES482986A1 (da)
FI (1)	FI69846C (da)
FR (1)	FR2444683A1 (da)
GB (1)	GB2037275B (da)
GR (1)	GR73899B (da)
IE (1)	IE48521B1 (da)
IL (1)	IL57909A (da)
IT (1)	IT1117760B (da)
LU (1)	LU81432A1 (da)
NL (1)	NL171271C (da)
NO (1)	NO158541C (da)
PH (1)	PH16327A (da)
SE (2)	SE436281B (da)
YU (1)	YU221082A (da)

1979
- 1979-05-22 SE SE7904483A patent/SE436281B/sv not_active IP Right Cessation
- 1979-05-23 DK DK213779A patent/DK160613C/da not_active IP Right Cessation
- 1979-05-29 CA CA000328553A patent/CA1141752A/en not_active Expired
- 1979-05-29 GR GR59209A patent/GR73899B/el unknown
- 1979-05-30 FI FI791732A patent/FI69846C/fi not_active IP Right Cessation
- 1979-05-31 NO NO791823A patent/NO158541C/no unknown
- 1979-06-01 GB GB7919231A patent/GB2037275B/en not_active Expired
- 1979-06-05 AU AU47774/79A patent/AU531779B2/en not_active Ceased
- 1979-06-12 FR FR7915037A patent/FR2444683A1/fr active Granted
- 1979-06-13 AT AT0421579A patent/AT364849B/de not_active IP Right Cessation
- 1979-06-13 CH CH554179A patent/CH642972A5/de not_active IP Right Cessation
- 1979-06-19 NL NLAANVRAGE7904805,A patent/NL171271C/xx not_active IP Right Cessation
- 1979-06-27 LU LU81432A patent/LU81432A1/fr unknown
- 1979-07-16 PH PH22784A patent/PH16327A/en unknown
- 1979-07-26 AR AR277486A patent/AR225898A1/es active
- 1979-07-27 IL IL57909A patent/IL57909A/xx not_active IP Right Cessation
- 1979-07-30 ES ES482986A patent/ES482986A1/es not_active Expired
- 1979-08-01 IT IT49919/79A patent/IT1117760B/it active
- 1979-08-08 IE IE1283/79A patent/IE48521B1/en not_active IP Right Cessation
1980
- 1980-04-16 ES ES490644A patent/ES8104301A1/es not_active Expired
1982
- 1982-10-01 YU YU02210/82A patent/YU221082A/xx unknown
1984
- 1984-03-02 SE SE8401182A patent/SE448630B/sv not_active IP Right Cessation
1990
- 1990-06-13 DK DK143990A patent/DK162055C/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
AT364849B (de)	1981-11-25
FI69846C (fi)	1986-05-26
NO791823L (no)	1980-06-19
NL171271B (nl)	1982-10-01
AU4777479A (en)	1980-06-26
DK160613C (da)	1991-09-23
YU221082A (en)	1983-04-30
ATA421579A (de)	1981-04-15
DK213779A (da)	1980-06-19
LU81432A1 (fr)	1980-01-22
SE8401182L (sv)	1984-03-02
IT1117760B (it)	1986-02-24
DK160613B (da)	1991-04-02
PH16327A (en)	1983-09-05
DK162055C (da)	1992-02-10
DK143990A (da)	1990-06-13
AR225898A1 (es)	1982-05-14
FI791732A7 (fi)	1980-06-19
FR2444683B1 (da)	1983-06-17
DK143990D0 (da)	1990-06-13
ES490644A0 (es)	1981-04-01
GR73899B (da)	1984-05-18
AU531779B2 (en)	1983-09-08
IL57909A0 (en)	1979-11-30
DK162055B (da)	1991-09-09
FR2444683A1 (fr)	1980-07-18
IL57909A (en)	1983-05-15
IE791283L (en)	1980-06-18
GB2037275A (en)	1980-07-09
SE7904483L (sv)	1980-06-19
NL171271C (nl)	1983-03-01
SE8401182D0 (sv)	1984-03-02
SE436281B (sv)	1984-11-26
IE48521B1 (en)	1985-02-20
NO158541B (no)	1988-06-20
ES8104301A1 (es)	1981-04-01
GB2037275B (en)	1983-01-19
IT7949919A0 (it)	1979-08-01
NO158541C (no)	1988-09-28
NL7904805A (nl)	1980-06-20
SE448630B (sv)	1987-03-09
CA1141752A (en)	1983-02-22
CH642972A5 (de)	1984-05-15
FI69846B (fi)	1985-12-31

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Legal Events

Date	Code	Title	Description
1997-04-01	FD1A	Patent lapsed	Effective date: 19970203