ES483865A1 - A PROCEDURE FOR THE PRODUCTION OF NEW DERIVATIVES OF -ALKYL-O-OXYBENZYLAMINE - Google Patents

A PROCEDURE FOR THE PRODUCTION OF NEW DERIVATIVES OF -ALKYL-O-OXYBENZYLAMINE

Info

Publication number
ES483865A1
ES483865A1 ES483865A ES483865A ES483865A1 ES 483865 A1 ES483865 A1 ES 483865A1 ES 483865 A ES483865 A ES 483865A ES 483865 A ES483865 A ES 483865A ES 483865 A1 ES483865 A1 ES 483865A1
Authority
ES
Spain
Prior art keywords
oxybenzylamine
alkyl
production
procedure
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES483865A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES483865A1 publication Critical patent/ES483865A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/11—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
    • C07C37/20—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms using aldehydes or ketones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un procedimiento para la producción de nuevos derivados de alfa-alquil-o-oxibencilamina, que están substituídos en el anillo fenílico por uno o a la más dos átomos de halógeno con número ordinal de 17 a 53, encontrándose el átomo o los átomos de halógeno en la posición meta con relación al radical aminoalquílico caracterizado porque se somete a cloración, bromación o yodación conveniente derivados correspondientes de alfa- alquilo-o-oxibencilamina que están substituidos en el anillo fenílico por a lo más un átomo de halógeno y los compuestos así obtenidos se obtienen en forma libre o en forma de sal.A process for the production of new alpha-alkyl-o-oxybenzylamine derivatives, which are substituted on the phenyl ring by one or at most two halogen atoms with ordinal number from 17 to 53, the halogen atom or atoms being in the meta position in relation to the aminoalkyl radical characterized in that it is subjected to convenient chlorination, bromination or iodination of the corresponding alpha-alkyl-o-oxybenzylamine derivatives that are substituted on the phenyl ring by at most one halogen atom and the compounds thus obtained are obtained in free form or in the form of salt.

ES483865A 1978-09-06 1979-09-04 A PROCEDURE FOR THE PRODUCTION OF NEW DERIVATIVES OF -ALKYL-O-OXYBENZYLAMINE Expired ES483865A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH937078 1978-09-06
CH437779 1979-05-10
CH437579 1979-05-10
CH557679 1979-06-14

Publications (1)

Publication Number Publication Date
ES483865A1 true ES483865A1 (en) 1980-04-16

Family

ID=27428769

Family Applications (1)

Application Number Title Priority Date Filing Date
ES483865A Expired ES483865A1 (en) 1978-09-06 1979-09-04 A PROCEDURE FOR THE PRODUCTION OF NEW DERIVATIVES OF -ALKYL-O-OXYBENZYLAMINE

Country Status (14)

Country Link
AU (1) AU5056579A (en)
DE (1) DE2934508A1 (en)
DK (1) DK362379A (en)
ES (1) ES483865A1 (en)
FI (1) FI792676A7 (en)
FR (1) FR2435461A1 (en)
GB (1) GB2029830A (en)
IL (1) IL58169A0 (en)
NL (1) NL7906557A (en)
PT (1) PT70142A (en)
SE (1) SE7907185L (en)
SU (1) SU895283A3 (en)
WO (1) WO1980000561A1 (en)
YU (1) YU215279A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8100078A (en) * 1980-01-14 1981-08-17 Sandoz Ag NEW 2-AMINOMETHYL-6-HALOGEN-PHENOLS, AND METHODS FOR PREPARING THESE PHENOLS AND MEDICINAL PRODUCTS CONTAINING THEM.
US5011989A (en) * 1987-10-09 1991-04-30 Sumitomo Chemical Company, Limited Optically active hydroxybenzylamine
US5231227A (en) * 1987-10-09 1993-07-27 Sumitomo Chemical Company, Limited Optically active hydroxybenzylamine derivative and process for producing said compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1493949A1 (en) * 1962-05-30 1969-07-10 Merck Ag E Process for the preparation of primary amines
NL149783B (en) * 1970-12-23 1976-06-15 Merck & Co Inc PROCESS FOR THE PREPARATION OF SUBSTITUTED AMINOMETHYLPHENOLS, OF THE NON-TOXIC PHARMACOLOGICALLY ACCEPTABLE SALTS DERIVED FROM THIS, PROCEDURE FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS AND THE PREPARED PREPARATIONS.
NL180978C (en) * 1972-10-23 1987-06-01 Thomae Gmbh Dr K METHOD FOR MANUFACTURING A PHARMACEUTICAL PREPARATION WITH SECRETORIC AND / OR ANTI-COUGHTING ACTION, AND A METHOD FOR PREPARING A COMPOUND SUITABLE FOR USE IN THE FOREGOING METHOD
AT332863B (en) * 1973-01-02 1976-10-25 Gerot Pharmazeutika PROCESS FOR THE PREPARATION OF NEW 2-AMINOMETHYL-4,6-DIHALOGENPHENOL DERIVATIVES AND THEIR ADDITIONAL SALTS WITH ACIDS

Also Published As

Publication number Publication date
FR2435461A1 (en) 1980-04-04
DK362379A (en) 1980-03-07
DE2934508A1 (en) 1980-03-20
YU215279A (en) 1983-04-30
SU895283A3 (en) 1981-12-30
PT70142A (en) 1979-10-01
SE7907185L (en) 1980-03-07
NL7906557A (en) 1980-03-10
GB2029830A (en) 1980-03-26
AU5056579A (en) 1980-03-13
FI792676A7 (en) 1981-01-01
IL58169A0 (en) 1979-12-30
WO1980000561A1 (en) 1980-04-03

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