ES484219A1 - Un procedimiento para la preparacion de triazinonas - Google Patents
Un procedimiento para la preparacion de triazinonasInfo
- Publication number
- ES484219A1 ES484219A1 ES484219A ES484219A ES484219A1 ES 484219 A1 ES484219 A1 ES 484219A1 ES 484219 A ES484219 A ES 484219A ES 484219 A ES484219 A ES 484219A ES 484219 A1 ES484219 A1 ES 484219A1
- Authority
- ES
- Spain
- Prior art keywords
- image
- formula
- compounds
- triazinones
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- -1 enol esters Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Heat Sensitive Colour Forming Recording (AREA)
Abstract
Un procedimiento para la preparación de triazinonas de fórmula general (I):**fórmula** en la que X representa HS o un grupo R1R2N- en el que R1 y R2 que pueden ser iguales o diferentes representan hidrógeno o un grupo alquilo de cadena lineal o ramificada que contiene de 1 a 4 átomos de carbono o un grupo bencilo y R3 representa un grupo alquilo de C3-7 o un grupo cicloalquilo de C3-7 que consiste en hidrolizar los ésteres enolicos isómeros.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7837215 | 1978-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES484219A1 true ES484219A1 (es) | 1980-10-01 |
Family
ID=10499745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES484219A Expired ES484219A1 (es) | 1978-09-18 | 1979-09-17 | Un procedimiento para la preparacion de triazinonas |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4308384A (es) |
| EP (1) | EP0009384A1 (es) |
| JP (1) | JPS5540700A (es) |
| AU (1) | AU5090979A (es) |
| CA (1) | CA1103670A (es) |
| DK (1) | DK388079A (es) |
| ES (1) | ES484219A1 (es) |
| FI (1) | FI792883A7 (es) |
| IE (1) | IE48829B1 (es) |
| ZA (1) | ZA794910B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5496927A (en) * | 1985-02-04 | 1996-03-05 | Merrell Pharmaceuticals Inc. | Peptidase inhibitors |
| DE4015946C3 (de) * | 1990-05-18 | 1996-06-20 | Kuesters Eduard Maschf | Ablaufplatte für eine Vorrichtung zum Aufbringen eines Flüssigkeitsfilms auf eine Warenbahn |
| EP0763055B1 (en) * | 1994-06-02 | 1999-11-03 | Merrell Pharmaceuticals Inc. | Perfluoroalkyl ketone inhibitors of elastase and processes for making the same |
| DE69522940T2 (de) * | 1994-06-02 | 2002-04-04 | Merrell Pharmaceuticals Inc., Cincinnati | Acylierte enolderivate als vorläufdrogen von elastaseinhibitoren |
| US5948886A (en) * | 1996-11-20 | 1999-09-07 | Hoechst Marion Roussel, Inc. | Acylated enol derivatives of α-ketoesters and α-ketoamides |
| US6172044B1 (en) | 1995-12-01 | 2001-01-09 | Aventis Pharmaceuticals Inc. | Acylated enol derivative of α-ketoesters and α-ketoamides |
| US6362178B1 (en) | 1997-11-12 | 2002-03-26 | Bayer Aktiengesellschaft | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
| DE19827640A1 (de) | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
| GB0113343D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel Heterocycles 2 |
| DE10135815A1 (de) | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
| DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
| US7462614B2 (en) * | 2003-04-01 | 2008-12-09 | Smithkline Beecham Corporation | Imidazotriazine compounds |
| DE102005009240A1 (de) | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3422194A (en) * | 1967-08-15 | 1969-01-14 | Smithkline Corp | The treatment of depression with imidazo(1,2-b)-as-triazines and compositions thereof |
| BE791025A (fr) * | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | Composes heterocycliques |
| GB1457873A (en) * | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
| DE2460889C2 (de) * | 1974-12-21 | 1983-06-09 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von 6-tert.-Butyl-3-mercapto-4-amino- 1.2.4-triazin-5(4H)-on |
| GB1584461A (en) * | 1977-03-25 | 1981-02-11 | Allen & Hanburys Ltd | Imidazotriazines imidazotriazinones and pharmaceutical compositions containing them |
-
1979
- 1979-09-14 US US06/075,732 patent/US4308384A/en not_active Expired - Lifetime
- 1979-09-17 ZA ZA00794910A patent/ZA794910B/xx unknown
- 1979-09-17 DK DK388079A patent/DK388079A/da unknown
- 1979-09-17 AU AU50909/79A patent/AU5090979A/en not_active Abandoned
- 1979-09-17 FI FI792883A patent/FI792883A7/fi not_active Application Discontinuation
- 1979-09-17 ES ES484219A patent/ES484219A1/es not_active Expired
- 1979-09-17 EP EP79301906A patent/EP0009384A1/en not_active Withdrawn
- 1979-09-17 IE IE1758/79A patent/IE48829B1/en unknown
- 1979-09-18 JP JP11999179A patent/JPS5540700A/ja active Pending
- 1979-09-18 CA CA335,892A patent/CA1103670A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK388079A (da) | 1980-03-19 |
| EP0009384A1 (en) | 1980-04-02 |
| IE48829B1 (en) | 1985-05-29 |
| CA1103670A (en) | 1981-06-23 |
| ZA794910B (en) | 1980-08-27 |
| IE791758L (en) | 1980-03-18 |
| JPS5540700A (en) | 1980-03-22 |
| US4308384A (en) | 1981-12-29 |
| AU5090979A (en) | 1980-02-21 |
| FI792883A7 (fi) | 1981-01-01 |
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