ES503985A0 - Un procedimiento para la preparacion de pirimidin-2-onas sustituidas - Google Patents
Un procedimiento para la preparacion de pirimidin-2-onas sustituidasInfo
- Publication number
- ES503985A0 ES503985A0 ES503985A ES503985A ES503985A0 ES 503985 A0 ES503985 A0 ES 503985A0 ES 503985 A ES503985 A ES 503985A ES 503985 A ES503985 A ES 503985A ES 503985 A0 ES503985 A0 ES 503985A0
- Authority
- ES
- Spain
- Prior art keywords
- group
- compounds
- susceptible
- phase
- normal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002159 abnormal effect Effects 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 230000022131 cell cycle Effects 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 239000002254 cytotoxic agent Substances 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 238000003683 electrophilic halogenation reaction Methods 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 230000031864 metaphase Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8023083 | 1980-07-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8300750A1 ES8300750A1 (es) | 1982-11-01 |
| ES503985A0 true ES503985A0 (es) | 1982-11-01 |
Family
ID=10514776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES503985A Granted ES503985A0 (es) | 1980-07-15 | 1981-07-15 | Un procedimiento para la preparacion de pirimidin-2-onas sustituidas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4650800A (es) |
| EP (1) | EP0044705B1 (es) |
| JP (1) | JPS5740483A (es) |
| AT (1) | ATE10256T1 (es) |
| AU (1) | AU7300281A (es) |
| CA (1) | CA1159830A (es) |
| DE (1) | DE3167186D1 (es) |
| DK (1) | DK315381A (es) |
| ES (1) | ES503985A0 (es) |
| NO (1) | NO812432L (es) |
| NZ (1) | NZ197715A (es) |
| ZA (1) | ZA814843B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8420610D0 (en) * | 1984-08-14 | 1984-09-19 | Glaxo Group Ltd | Chemical compounds |
| JPH0679095B2 (ja) * | 1986-04-03 | 1994-10-05 | 旭硝子株式会社 | プラスチツククラツド光伝送フアイバ− |
| RU2102985C1 (ru) * | 1995-11-10 | 1998-01-27 | Владимир Константинович Васильев | Способ подавления гиперактивных клеток |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1561290A (en) * | 1975-10-16 | 1980-02-20 | Nyegaard & Co As | Pyrimid - 2 - ones |
| ES498337A0 (es) * | 1980-01-07 | 1982-06-01 | Nyegaard & Co As | Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas |
-
1981
- 1981-07-14 CA CA000381682A patent/CA1159830A/en not_active Expired
- 1981-07-14 NZ NZ197715A patent/NZ197715A/en unknown
- 1981-07-15 AT AT81303255T patent/ATE10256T1/de not_active IP Right Cessation
- 1981-07-15 ZA ZA814843A patent/ZA814843B/xx unknown
- 1981-07-15 JP JP56110635A patent/JPS5740483A/ja active Pending
- 1981-07-15 NO NO812432A patent/NO812432L/no unknown
- 1981-07-15 DE DE8181303255T patent/DE3167186D1/de not_active Expired
- 1981-07-15 ES ES503985A patent/ES503985A0/es active Granted
- 1981-07-15 DK DK315381A patent/DK315381A/da not_active Application Discontinuation
- 1981-07-15 EP EP81303255A patent/EP0044705B1/en not_active Expired
- 1981-07-15 AU AU73002/81A patent/AU7300281A/en not_active Abandoned
-
1983
- 1983-05-19 US US06/496,093 patent/US4650800A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3167186D1 (en) | 1984-12-20 |
| US4650800A (en) | 1987-03-17 |
| ZA814843B (en) | 1983-02-23 |
| ATE10256T1 (de) | 1984-11-15 |
| CA1159830A (en) | 1984-01-03 |
| EP0044705B1 (en) | 1984-11-14 |
| AU7300281A (en) | 1982-01-21 |
| DK315381A (da) | 1982-01-16 |
| ES8300750A1 (es) | 1982-11-01 |
| EP0044705A1 (en) | 1982-01-27 |
| NO812432L (no) | 1982-01-18 |
| NZ197715A (en) | 1984-12-14 |
| JPS5740483A (en) | 1982-03-06 |
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