ES505803A0 - Un procedimiento para la estabilizacion de una composicion farmaceutica de trihidrato de amoxicilina y de clavulanato depotasio. - Google Patents

Un procedimiento para la estabilizacion de una composicion farmaceutica de trihidrato de amoxicilina y de clavulanato depotasio.

Info

Publication number: ES505803A0
Authority: ES; Spain
Prior art keywords: depotassium; clavulanate; stabilization; procedure; pharmaceutical composition
Prior art date: 1980-09-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES505803A

Other languages

English (en)

Other versions

ES8307095A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Beecham Group PLC

Original Assignee

Beecham Group PLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-09-27

Filing date

1981-09-25

Publication date

1983-06-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10516342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES505803(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1981-09-25 Application filed by Beecham Group PLC filed Critical Beecham Group PLC

1983-06-16 Publication of ES505803A0 publication Critical patent/ES505803A0/es

1983-06-16 Publication of ES8307095A1 publication Critical patent/ES8307095A1/es

Status Expired legal-status Critical Current

Links

HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title 1
LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical group C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 title 1
229960004920 amoxicillin trihydrate Drugs 0.000 title 1
229940090805 clavulanate Drugs 0.000 title 1
HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title 1
238000000034 method Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
230000006641 stabilisation Effects 0.000 title 1
238000011105 stabilization Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES505803A 1980-09-27 1981-09-25 Un procedimiento para la estabilizacion de una composicion farmaceutica de trihidrato de amoxicilina y de clavulanato depotasio. Expired ES8307095A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8031298		1980-09-27

Publications (2)

Publication Number	Publication Date
ES505803A0 true ES505803A0 (es)	1983-06-16
ES8307095A1 ES8307095A1 (es)	1983-06-16

Family

ID=10516342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES505803A Expired ES8307095A1 (es)	1980-09-27	1981-09-25	Un procedimiento para la estabilizacion de una composicion farmaceutica de trihidrato de amoxicilina y de clavulanato depotasio.

Country Status (15)

Country	Link
US (1)	US4537887A (es)
EP (1)	EP0049061B1 (es)
JP (1)	JPS5791921A (es)
AU (1)	AU549321B2 (es)
CA (1)	CA1187796A (es)
DE (1)	DE3172028D1 (es)
ES (1)	ES8307095A1 (es)
GB (1)	GB2084016B (es)
GR (1)	GR75049B (es)
HK (1)	HK17386A (es)
IE (1)	IE51597B1 (es)
MY (1)	MY8600353A (es)
NZ (1)	NZ198241A (es)
PT (1)	PT73686A (es)
ZA (1)	ZA816272B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0080862B1 (en) *	1981-12-02	1985-09-25	Beecham Group Plc	Pharmaceutical formulation comprising beta-lactam antibiotics
JPS59104319A (ja) *	1982-12-06	1984-06-16	Chugai Pharmaceut Co Ltd	抗菌剤およびそのキツト
DE3887179T2 (de) *	1987-03-02	1994-06-16	Brocades Pharma Bv	Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US5211958A (en) *	1987-11-30	1993-05-18	Gist-Brocades, N.V.	Pharmaceutical composition and process for its preparation
EP0330284B1 (en) *	1988-02-25	1994-07-27	Yamanouchi Europe B.V.	Process for the preparation of a pharmaceutical granulate
US5643902A (en) *	1990-04-26	1997-07-01	Pfizer Inc.	Veterinary treatment
GB9408117D0 (en) *	1994-04-23	1994-06-15	Smithkline Beecham Corp	Pharmaceutical formulations
GB9413542D0 (en) *	1994-07-05	1994-08-24	Smithkline Beecham Plc	Pharmaceutical formulations
ATE208333T1 (de) *	1994-08-05	2001-11-15	West Pharm Serv Cornall Ltd	Behälter für feuchtickeitsempfindliche stoffe und entsprechendes verfahren zum trocknen und zur reduktion
GB9416600D0 (en) *	1994-08-17	1994-10-12	Smithkline Beecham Plc	Pharmaceutical formulation
DZ1926A1 (fr) *	1994-09-03	2002-02-17	Smithkline Beckman P L C	Formulations pharmaceutiques.
ES2079327B1 (es) *	1994-12-13	1996-08-01	Lilly Sa	Formulaciones farmaceuticas de cefaclor.
DZ2028A1 (fr) *	1995-05-03	2002-10-23	Smithkline Beecham Plc	Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US20030109503A1 (en) *	1995-06-06	2003-06-12	Smithkline Beecham P.L.C.	Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
EP1093812A3 (en) *	1995-09-07	2001-06-06	SmithKline Beecham Corporation	Amoxycillin and clavulanate containing pharmaceutical formulation
ITMI952354A1 (it) *	1995-11-16	1997-05-16	Smithkline Beecham Spa	Composizione farmaceutica
US5801796A (en) *	1996-05-10	1998-09-01	International Business Machines Corporation	Stacked parallax-free liquid crystal display cell
GB9617780D0 (en) *	1996-08-24	1996-10-02	Smithkline Beecham Plc	Method of treatment
US20030124187A1 (en) *	1997-02-14	2003-07-03	Smithkline Beecham Laboratoires Pharmaceutiques,	Pharmaceutical formulations comprising amoxycillin and clavulanate
IL131201A (en) *	1997-02-14	2005-06-19	Smithkline Beecham Lab	Pharmaceutical formulations comprising amoxycillin and clavulanate
US6296871B1 (en) *	1998-04-12	2001-10-02	Ranbaxy Laboratories Limited	Stable solid pharmaceutical compositions containing enalapril maleate
US6177421B1 (en)	1999-05-04	2001-01-23	Fuisz International Ltd.	Amoxicillin and clavulanate composition
IE990159A1 (en) *	1999-02-26	2000-09-20	Fuisz Internat Ltd	Storage Stable Amoxycillin and Clavulanate Suspension Composition.
US6294199B1 (en) *	1999-04-13	2001-09-25	Beecham Pharmaceuticals (Pte) Limited	Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) *	1999-04-13	2007-07-31	Beecham Pharmaceuticals (Pte) Limited	Method of treating a bacterial infection
US6878386B1 (en)	1999-04-13	2005-04-12	Beecham Pharmaceuticals (Pte) Limited	Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6610681B1 (en) *	1999-08-16	2003-08-26	Revaax Pharmaceuticals, Llc	Neurotherapeutic clavulanate composition and method
US6426342B2 (en) *	1999-08-16	2002-07-30	Revaax Pharmaceuticals, Llc	Use of β-lactamase inhibitors as neuroprotectants
US6756057B2 (en)	2000-10-12	2004-06-29	Beecham Pharmaceuticals (Pte) Limited	Amoxicillin and potassium clavulanate dosage form
WO2002030392A2 (en)	2000-10-12	2002-04-18	Beecham Pharmaceuticals (Pte) Limited	Formulation containing amoxicillin
CA2359812C (en) *	2000-11-20	2004-02-10	The Procter & Gamble Company	Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
KR100456833B1 (ko) *	2002-08-01	2004-11-10	주식회사 대웅	아목시실린 및 클라불라네이트를 함유하는 유핵정
EP1902708A1 (de)	2006-09-25	2008-03-26	Losan Pharma GmbH	Wirkstoff enthaltende stabilisierte feste Arzneimittelformen und Verfahren zu ihrer Herstellung
EP2214680A4 (en)	2007-10-26	2010-12-29	Rexahn Pharmaceuticals Inc	PHARMACEUTICAL FORMULATION OF CLAVLANIC ACID
MX2011011459A (es) *	2009-04-29	2011-11-18	Rexahn Pharmaceuticals Inc	Formulacion de clavulanato para neuroproteccion y tratamiento de trastornos neurodegenerativos.
CA2903283C (en)	2013-03-15	2023-09-05	Braintree Laboratories, Inc.	Dual use oral pharmaceutical composition tablets of sulfate salts and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE888444C (de) *	1951-11-10	1953-08-31	Benckiser Gmbh Joh A	Verfahren zum Tablettieren von hygroskopischen Praeparaten
US3432593A (en) *	1963-09-18	1969-03-11	Key Pharm Inc	Delayed and sustained release type pharmaceutical preparation
GB1209634A (en) *	1967-06-29	1970-10-21	Rit Rech Ind Therapeut	Stabilized antibiotic compositions for animal feeding and process for preparing them
DE2512247A1 (de) *	1975-03-20	1976-10-14	Thomae Gmbh Dr K	Gegen feuchtigkeit stabilisierte presslinge mit feuchtigkeitsempfindlichen inhaltsstoffen
US4140755A (en) *	1976-02-13	1979-02-20	Hoffmann-La Roche Inc.	Sustained release tablet formulations
JO984B1 (en) *	1977-10-11	1979-12-01	بيتشام غروب ليمتد	A dry pharmaceutical compound with a suitable dosage unit for oral administration
IL58461A0 (en) *	1978-10-27	1980-01-31	Beecham Group Ltd	Intramammary compositions comprising a clavulanic acid salt
US4226849A (en) *	1979-06-14	1980-10-07	Forest Laboratories Inc.	Sustained release therapeutic compositions

1981
- 1981-09-02 NZ NZ198241A patent/NZ198241A/xx unknown
- 1981-09-08 EP EP81304086A patent/EP0049061B1/en not_active Expired
- 1981-09-08 DE DE8181304086T patent/DE3172028D1/de not_active Expired
- 1981-09-10 ZA ZA816272A patent/ZA816272B/xx unknown
- 1981-09-14 GB GB8127649A patent/GB2084016B/en not_active Expired
- 1981-09-16 PT PT73686A patent/PT73686A/pt unknown
- 1981-09-23 GR GR66117A patent/GR75049B/el unknown
- 1981-09-25 AU AU75684/81A patent/AU549321B2/en not_active Expired
- 1981-09-25 CA CA000386670A patent/CA1187796A/en not_active Expired
- 1981-09-25 ES ES505803A patent/ES8307095A1/es not_active Expired
- 1981-09-25 IE IE2232/81A patent/IE51597B1/en not_active IP Right Cessation
- 1981-09-28 JP JP56153513A patent/JPS5791921A/ja active Granted
1983
- 1983-10-05 US US06/539,099 patent/US4537887A/en not_active Expired - Lifetime
1986
- 1986-03-13 HK HK173/86A patent/HK17386A/en not_active IP Right Cessation
- 1986-12-30 MY MY353/86A patent/MY8600353A/xx unknown

Also Published As

Publication number	Publication date
DE3172028D1 (en)	1985-10-03
JPS5791921A (en)	1982-06-08
PT73686A (pt)	1981-10-01
AU7568481A (en)	1982-04-08
JPH0155244B2 (es)	1989-11-22
IE51597B1 (en)	1987-01-21
EP0049061A1 (en)	1982-04-07
US4537887A (en)	1985-08-27
ES8307095A1 (es)	1983-06-16
GB2084016B (en)	1985-04-17
MY8600353A (en)	1986-12-31
GB2084016A (en)	1982-04-07
NZ198241A (en)	1983-12-16
GR75049B (es)	1984-07-12
AU549321B2 (en)	1986-01-23
HK17386A (en)	1986-03-21
EP0049061B1 (en)	1985-08-28
CA1187796A (en)	1985-05-28
IE812232L (en)	1982-03-27
ZA816272B (en)	1982-09-29

Publication	Publication Date	Title
DE3578620D1 (de)	1990-08-16	Arzneimittel zur aeusserlichen anwendung.
IL55660A (en)	1981-09-13	Pharmaceutical compositions containing amoxycillin trihydrate and potassium clavulanate
ES504905A0 (es)	1983-02-01	Un procedimiento para la preparacion de una nueva formulacion de bacampicilina.
ES518879A0 (es)	1984-10-01	Un procedimiento para la preparacion de una composicion termoplastica cargada.
ES503011A0 (es)	1982-04-16	Un procedimiento para la preparacion de una formulacion por-tadora de farmacos,biodegradable y magneticamente localiza- ble
ATE22007T1 (de)	1986-09-15	Pharmazeutische mischung.
FI832382A7 (fi)	1983-12-31	Fenyylialfa- asyylioksiasetamidijohdannaiset ja niiden terapeuttinen käyttö.
ES490294A0 (es)	1981-04-16	Un procedimiento para la preparacion de una composicion blanqueante y limpiadora.
PT73686A (pt)	1981-10-01	Pharmaceutical formulation
ES524271A0 (es)	1984-11-16	Un procedimiento para la preparacion de nuevos derivados de daunorrubicina y doxorrubicina.
ES503790A0 (es)	1982-11-01	Un procedimiento para la preparacion de una composicion de derivados del imidazor.
FI812810A7 (fi)	1982-03-13	Ammoniometyyliyhdisteitä, menetelmiä niiden valmistamiseksi, näitä yhdisteitä sisältäviä farmaseuttisia valvalmisteita ja viimemainittujen käyttö.
NL190923B (nl)	1994-06-01	Farmaceutisch preparaat omvattende ibuprofen en caffeine.
DE3382112D1 (de)	1991-02-21	Pharmazeutische zusammensetzung.
ES504741A0 (es)	1984-05-16	Un procedimiento para la preparacion de una composicion esporicida de dialdehido-diol.
ES516864A0 (es)	1983-09-16	Procedimiento para la preparacion de derivados de penem.
FI832519A7 (fi)	1984-01-13	Farmaseuttisia menetelmiä ja koostumuksia.
ES521277A0 (es)	1984-06-16	Un procedimiento para la preparacion de derivados de penem sustituidos.
NO163284C (no)	1990-05-02	Analogifremgangsm te til fremstilling av terapeutisk aktive karbapenem-antibiotika.
FI852743A7 (fi)	1986-01-14	Asetyleenisiä fenoksipropanolijohdannaisia ja farmaseuttisia koostumuksia hypertoniahoitamiseksi.
FI832520A7 (fi)	1984-01-13	Farmaseuttisia menetelmiä ja koostumuksia.
FI810637A7 (fi)	1981-09-08	Lääkeaineen imeytymistä edistävien apuaineiden käyttö - laktaamiantibiootteja sisältävissä valmisteissa.
FI841584A7 (fi)	1984-04-19	Menetelmä mannitolin ja sorbitolin valmistamiseksi.
FI832426A7 (fi)	1984-01-09	Meptatsinolia ja ibuprofeenia sisältäviä farmaseuttisia koostumuksia.
MX6962E (es)	1987-01-08	Procedimiento para la preparacion de una composicion farmaceutica antidiarreica