ES508655A0 - "procedimiento para la preparacion de 3,1-benzoxazin-2-onas". - Google Patents

"procedimiento para la preparacion de 3,1-benzoxazin-2-onas".

Info

Publication number: ES508655A0
Authority: ES; Spain
Prior art keywords: group; hydrogen; alkyl; methyl; hydrogen atom
Prior art date: 1980-07-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES508655A

Other languages

English (en)

Other versions

ES8300727A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CH Boehringer Sohn AG and Co KG

Original Assignee

CH Boehringer Sohn AG and Co KG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-07-12

Filing date

1982-01-12

Publication date

1982-11-01

1982-01-12 Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG

1982-11-01 Publication of ES8300727A1 publication Critical patent/ES8300727A1/es

1982-11-01 Publication of ES508655A0 publication Critical patent/ES508655A0/es

Status Granted legal-status Critical Current

Links

125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
229910052801 chlorine Inorganic materials 0.000 abstract 4
125000001309 chloro group Chemical group Cl* 0.000 abstract 4
-1 hydroxy, methyl Chemical group 0.000 abstract 4
229910052731 fluorine Inorganic materials 0.000 abstract 3
239000011737 fluorine Substances 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
208000001953 Hypotension Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
208000021822 hypotensive Diseases 0.000 abstract 1
230000001077 hypotensive effect Effects 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000003195 tocolytic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

ES508655A 1980-07-12 1982-01-12 "procedimiento para la preparacion de 3,1-benzoxazin-2-onas". Granted ES508655A0 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19803026534 DE3026534A1 (de)	1980-07-12	1980-07-12	3,1-benzoxazin-2-one, ihre herstellung und verwendung

Publications (2)

Publication Number	Publication Date
ES8300727A1 ES8300727A1 (es)	1982-11-01
ES508655A0 true ES508655A0 (es)	1982-11-01

Family

ID=6107085

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
ES503837A Expired ES8205402A1 (es)	1980-07-12	1981-07-10	Procedimiento para la preparacion de 3,1-benzoxazin-2-onas
ES508653A Granted ES508653A0 (es)	1980-07-12	1982-01-12	"procedimiento para la preparacion de 3,1-benzoxazin-2-onas".
ES508655A Granted ES508655A0 (es)	1980-07-12	1982-01-12	"procedimiento para la preparacion de 3,1-benzoxazin-2-onas".
ES508654A Expired ES8300726A1 (es)	1980-07-12	1982-01-12	"procedimiento para la preparacion de 3,1-benzoxazin-2-onas".

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
ES503837A Expired ES8205402A1 (es)	1980-07-12	1981-07-10	Procedimiento para la preparacion de 3,1-benzoxazin-2-onas
ES508653A Granted ES508653A0 (es)	1980-07-12	1982-01-12	"procedimiento para la preparacion de 3,1-benzoxazin-2-onas".

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES508654A Expired ES8300726A1 (es)	1980-07-12	1982-01-12	"procedimiento para la preparacion de 3,1-benzoxazin-2-onas".

Country Status (25)

Country	Link
US (1)	US4341778A (es)
EP (1)	EP0043940B1 (es)
JP (1)	JPS5748975A (es)
KR (1)	KR850000755B1 (es)
AT (1)	ATE9336T1 (es)
AU (1)	AU540916B2 (es)
CA (1)	CA1165317A (es)
DD (1)	DD202018A5 (es)
DE (2)	DE3026534A1 (es)
DK (1)	DK149851C (es)
ES (4)	ES8205402A1 (es)
FI (1)	FI74703C (es)
GB (1)	GB2080296B (es)
GR (1)	GR74333B (es)
HK (1)	HK98286A (es)
HU (1)	HU183515B (es)
IE (1)	IE52508B1 (es)
IL (1)	IL63285A (es)
NO (1)	NO158578C (es)
NZ (1)	NZ197678A (es)
PH (1)	PH17425A (es)
PT (1)	PT73338B (es)
SG (1)	SG77686G (es)
YU (1)	YU170181A (es)
ZA (1)	ZA814687B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4446319A (en) *	1981-04-28	1984-05-01	Takeda Chemical Industries, Ltd.	Aminocyclitols and their production
JPS62238288A (ja) *	1986-04-04	1987-10-19	Nippon Tokushu Noyaku Seizo Kk	環状カルバメ−ト及び農園芸用殺菌剤
FR2636065B1 (fr) *	1988-09-08	1993-05-07	Fabre Sa Pierre	Nouveaux derives de dihydro-2,3 arylacoylaminoalcoyl-3 4h-benzoxazine-1,3 ones-4, leur preparation et leur application en tant que medicaments utiles en therapeutique
JP2807577B2 (ja) *	1990-06-15	1998-10-08	エーザイ株式会社	環状アミド誘導体
FR2680172B1 (fr) *	1991-08-05	1993-11-19	Fabre Medicament Pierre	Nouvelles piperazinylalcoyl-3 dihydro-2,3 4h-benzoxazine-1,3 ones-4 substituees, leur preparation et leur application en therapeutique.
EP0805681A4 (en) *	1995-01-24	1998-05-06	Merck & Co Inc	TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS
US5874430A (en) *	1996-10-02	1999-02-23	Dupont Pharmaceuticals Company	4,4-disubstitued-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same
DE102004003428A1 (de) *	2004-01-23	2005-08-11	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel
JPWO2006077821A1 (ja) *	2005-01-19	2008-06-19	大日本住友製薬株式会社	アルドステロン受容体調節剤としての芳香族スルホン化合物
DE102005008921A1 (de) *	2005-02-24	2006-08-31	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittel zur Behandlung von Atemwegserkrankungen
US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
UY30552A1 (es) *	2006-08-22	2008-03-31	Boehringer Ingelheim Int	Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones
PE20080425A1 (es) *	2006-08-22	2008-06-16	Boehringer Ingelheim Int	Formulacion aerosol para la inhalacion de beta-agonistas
EP2056836A1 (en) *	2006-08-22	2009-05-13	Boehringer Ingelheim International GmbH	Powder formulations for inhalation containing enantiomerically pure beta-agonists
PE20080610A1 (es) *	2006-08-22	2008-07-15	Boehringer Ingelheim Int	Nuevos beta-agonistas enantiomericamente puros, procedimientos para su preparacion y uso como medicamentos
EP2093219A1 (de)	2008-02-22	2009-08-26	Boehringer Ingelheim International Gmbh	Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3526621A (en) *	1966-08-03	1970-09-01	Farmaceutical Italia Soc	Substituted 3,1-benzoxazin-2-one
DE2609645A1 (de) *	1976-03-09	1977-09-15	Boehringer Sohn Ingelheim	Aminoalkylheterocyclen
US4163053A (en) *	1977-12-27	1979-07-31	Schering Corporation	Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides
DD144050A5 (de) *	1978-06-05	1980-09-24	Ciba Geigy Ag	Verfahren zur herstellung von n-alkylierten aminoalkoholen
DE2833140A1 (de) *	1978-07-28	1980-02-07	Boehringer Sohn Ingelheim	Neue n-substituierte heterocyclen

1980
- 1980-07-12 DE DE19803026534 patent/DE3026534A1/de not_active Withdrawn
1981
- 1981-06-22 AT AT81104787T patent/ATE9336T1/de not_active IP Right Cessation
- 1981-06-22 DE DE8181104787T patent/DE3166003D1/de not_active Expired
- 1981-06-22 EP EP81104787A patent/EP0043940B1/de not_active Expired
- 1981-07-06 US US06/280,349 patent/US4341778A/en not_active Expired - Fee Related
- 1981-07-07 PH PH25873A patent/PH17425A/en unknown
- 1981-07-09 YU YU01701/81A patent/YU170181A/xx unknown
- 1981-07-09 PT PT73338A patent/PT73338B/pt unknown
- 1981-07-10 IL IL63285A patent/IL63285A/xx unknown
- 1981-07-10 CA CA000381559A patent/CA1165317A/en not_active Expired
- 1981-07-10 ES ES503837A patent/ES8205402A1/es not_active Expired
- 1981-07-10 HU HU812036A patent/HU183515B/hu unknown
- 1981-07-10 GB GB8121321A patent/GB2080296B/en not_active Expired
- 1981-07-10 IE IE1567/81A patent/IE52508B1/en unknown
- 1981-07-10 NO NO812355A patent/NO158578C/no unknown
- 1981-07-10 ZA ZA814687A patent/ZA814687B/xx unknown
- 1981-07-10 FI FI812183A patent/FI74703C/fi not_active IP Right Cessation
- 1981-07-10 GR GR65470A patent/GR74333B/el unknown
- 1981-07-10 DK DK306781A patent/DK149851C/da not_active IP Right Cessation
- 1981-07-10 DD DD81231670A patent/DD202018A5/de unknown
- 1981-07-10 NZ NZ197678A patent/NZ197678A/en unknown
- 1981-07-10 AU AU72731/81A patent/AU540916B2/en not_active Ceased
- 1981-07-11 KR KR8102523A patent/KR850000755B1/ko not_active Expired
- 1981-07-13 JP JP56109186A patent/JPS5748975A/ja active Pending
1982
- 1982-01-12 ES ES508653A patent/ES508653A0/es active Granted
- 1982-01-12 ES ES508655A patent/ES508655A0/es active Granted
- 1982-01-12 ES ES508654A patent/ES8300726A1/es not_active Expired
1986
- 1986-09-26 SG SG776/86A patent/SG77686G/en unknown
- 1986-12-18 HK HK982/86A patent/HK98286A/xx unknown

Also Published As

Publication number	Publication date
YU170181A (en)	1983-10-31
CA1165317A (en)	1984-04-10
IE52508B1 (en)	1987-11-25
DE3026534A1 (de)	1982-03-18
FI812183L (fi)	1982-01-13
EP0043940B1 (de)	1984-09-12
DK149851C (da)	1987-05-04
AU540916B2 (en)	1984-12-06
FI74703B (fi)	1987-11-30
NO158578C (no)	1988-10-05
NZ197678A (en)	1984-12-14
PH17425A (en)	1984-08-08
HU183515B (en)	1984-05-28
KR850000755B1 (en)	1985-05-25
DK149851B (da)	1986-10-13
ES508654A0 (es)	1982-11-01
SG77686G (en)	1987-02-27
FI74703C (fi)	1988-03-10
ATE9336T1 (de)	1984-09-15
DE3166003D1 (en)	1984-10-18
IL63285A (en)	1985-03-31
DD202018A5 (de)	1983-08-24
PT73338A (de)	1981-08-01
ES8300726A1 (es)	1982-11-01
ES503837A0 (es)	1982-06-01
GR74333B (es)	1984-06-25
EP0043940A1 (de)	1982-01-20
KR830006248A (ko)	1983-09-20
NO812355L (no)	1982-01-13
IL63285A0 (en)	1981-10-30
DK306781A (da)	1982-01-13
GB2080296B (en)	1983-09-28
HK98286A (en)	1986-12-24
PT73338B (en)	1983-06-20
ES8205402A1 (es)	1982-06-01
GB2080296A (en)	1982-02-03
US4341778A (en)	1982-07-27
ES8300727A1 (es)	1982-11-01
NO158578B (no)	1988-06-27
ES8300725A1 (es)	1982-11-01
ES508653A0 (es)	1982-11-01
JPS5748975A (en)	1982-03-20
ZA814687B (en)	1983-03-30
IE811567L (en)	1982-01-12
AU7273181A (en)	1982-09-16

Publication	Publication Date	Title
ES508654A0 (es)	1982-11-01	"procedimiento para la preparacion de 3,1-benzoxazin-2-onas".
DK422583A (da)	1984-03-19	Fremgangsmaade til fremstilling af diazobicyclo-(3,3,1)-nonaner
ATE34575T1 (de)	1988-06-15	Neue theophyllin-derivate und verfahren zu ihrer herstellung.
IL64647A (en)	1985-10-31	2,8-disubstituted-4-thiomorpholino-pyrimido(5,4-d)pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
ES514816A0 (es)	1983-10-16	"procedimiento para la preparacion de compuestos de 1-fenil-2-aminocarbonilindol".
PT83786A (de)	1986-12-01	Neue basisch substituierte pyridinverbindungen verfahren zu ihrer herstellung die sie enthaltenden arzneimittel und ihre verwendung
ES464013A1 (es)	1978-07-16	Procedimiento para preparar derivados sustituidos de orto- fenilendiamina.
DE3166645D1 (en)	1984-11-15	Dibenzoxazonine, dibenzoxazecine, dibenzoxaazacycloundecane derivatives and their corresponding thia- and aza derivatives, their preparation and pharmaceutical compositions