ES512704A0 - Procedimiento para preparar derivados de indol o de indolina. - Google Patents

Procedimiento para preparar derivados de indol o de indolina.

Info

Publication number
ES512704A0
ES512704A0 ES512704A ES512704A ES512704A0 ES 512704 A0 ES512704 A0 ES 512704A0 ES 512704 A ES512704 A ES 512704A ES 512704 A ES512704 A ES 512704A ES 512704 A0 ES512704 A0 ES 512704A0
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
hydrogen
indolina
indol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES512704A
Other languages
English (en)
Other versions
ES8303332A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of ES8303332A1 publication Critical patent/ES8303332A1/es
Publication of ES512704A0 publication Critical patent/ES512704A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5456—Arylalkanephosphonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
ES512704A 1980-06-18 1982-05-31 Procedimiento para preparar derivados de indol o de indolina. Granted ES512704A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8019948 1980-06-18

Publications (2)

Publication Number Publication Date
ES8303332A1 ES8303332A1 (es) 1983-02-01
ES512704A0 true ES512704A0 (es) 1983-02-01

Family

ID=10514138

Family Applications (4)

Application Number Title Priority Date Filing Date
ES503097A Expired ES8300091A1 (es) 1980-06-18 1981-06-16 Procedimiento para preparar derivados de indol o de indolina
ES512704A Granted ES512704A0 (es) 1980-06-18 1982-05-31 Procedimiento para preparar derivados de indol o de indolina.
ES512706A Granted ES512706A0 (es) 1980-06-18 1982-05-31 Procedimiento para preparar derivados de indol o de indolina.
ES512705A Granted ES512705A0 (es) 1980-06-18 1982-05-31 Procedimiento para preparar derivados de indol o de indolina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES503097A Expired ES8300091A1 (es) 1980-06-18 1981-06-16 Procedimiento para preparar derivados de indol o de indolina

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES512706A Granted ES512706A0 (es) 1980-06-18 1982-05-31 Procedimiento para preparar derivados de indol o de indolina.
ES512705A Granted ES512705A0 (es) 1980-06-18 1982-05-31 Procedimiento para preparar derivados de indol o de indolina.

Country Status (22)

Country Link
US (1) US4493843A (es)
EP (1) EP0042298B1 (es)
JP (1) JPS5728048A (es)
KR (1) KR850001470B1 (es)
AT (1) ATE9329T1 (es)
AU (1) AU539678B2 (es)
CA (1) CA1149811A (es)
DE (1) DE3165998D1 (es)
DK (1) DK264281A (es)
ES (4) ES8300091A1 (es)
FI (1) FI811889A7 (es)
GB (1) GB2078736B (es)
GR (1) GR75701B (es)
HK (2) HK92684A (es)
HU (1) HU183480B (es)
IE (1) IE52102B1 (es)
IL (1) IL63110A (es)
MY (2) MY8500975A (es)
NZ (1) NZ197441A (es)
PH (1) PH16357A (es)
SG (2) SG68984G (es)
ZA (1) ZA814057B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1114028E (pt) * 1998-08-26 2007-02-28 Aventis Pharma Ltd Aza-biciclos moduladores da inibição da adesão celular
GB9818641D0 (en) * 1998-08-26 1998-10-21 Rh Ne Poulenc Rorer Limited Chemical compounds
WO2001044184A1 (en) * 1999-12-16 2001-06-21 Eli Lilly And Company Synthesis of indole-containing spla2 inhibitors
EP1511729A4 (en) 2002-05-22 2006-09-06 Errant Gene Therapeutics Llc HISTONDEACETYLASEINHIBITORS BASED ON ALPHACHALCOGEN METHYL CARBONYL COMPOUNDS
WO2005090303A1 (en) * 2004-03-15 2005-09-29 Eli Lilly And Company 4- (5- (aminomethyl) -indole-1-ylmethyl) -benzamide derivatives and related compounds as opioid receptor antagonists for the treatment of obesity
JP6217561B2 (ja) * 2014-08-21 2017-10-25 信越化学工業株式会社 新規オニウム塩化合物及びレジスト組成物並びにパターン形成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3076814A (en) * 1954-04-28 1963-02-05 Upjohn Co Novel process for the preparation of tryptophols and to novel compounds produced therein
DE2237361A1 (de) * 1972-07-29 1974-02-14 Boehringer Mannheim Gmbh (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben
US3992392A (en) * 1973-04-27 1976-11-16 The Ohio State University Research Foundation Synthesis of indoles from anilines and intermediates therein
US3901899A (en) * 1973-04-27 1975-08-26 Univ Ohio State Res Found Synthesis of indoles from anilines and intermediates therein
US3950343A (en) * 1973-11-06 1976-04-13 Ayerst, Mckenna And Harrison Ltd. Pyrroloisoquinoline derivatives
FI59246C (fi) * 1974-06-24 1981-07-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin
DE2909779A1 (de) * 1979-03-13 1980-09-18 Thomae Gmbh Dr K Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
KR830006205A (ko) 1983-09-20
ATE9329T1 (de) 1984-09-15
IE811344L (en) 1981-12-18
ES503097A0 (es) 1982-10-01
ES8303333A1 (es) 1983-02-01
MY8500975A (en) 1985-12-31
KR850001470B1 (ko) 1985-10-10
HK92485A (en) 1985-11-29
ES8305327A1 (es) 1983-04-01
DK264281A (da) 1981-12-19
CA1149811A (en) 1983-07-12
EP0042298A1 (en) 1981-12-23
IE52102B1 (en) 1987-06-24
ES512706A0 (es) 1983-04-01
ES8300091A1 (es) 1982-10-01
AU539678B2 (en) 1984-10-11
HK92684A (en) 1984-11-30
SG73085G (en) 1986-05-02
ES8303332A1 (es) 1983-02-01
ZA814057B (en) 1982-07-28
NZ197441A (en) 1984-11-09
HU183480B (en) 1984-05-28
MY8600409A (en) 1986-12-31
GB2078736A (en) 1982-01-13
IL63110A (en) 1986-10-31
SG68984G (en) 1985-03-15
JPS5728048A (en) 1982-02-15
FI811889L (fi) 1981-12-19
GB2078736B (en) 1984-03-07
US4493843A (en) 1985-01-15
FI811889A7 (fi) 1981-12-19
DE3165998D1 (de) 1984-10-18
PH16357A (en) 1983-09-05
ES512705A0 (es) 1983-02-01
EP0042298B1 (en) 1984-09-12
AU7186481A (en) 1981-12-24
GR75701B (es) 1984-08-02

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