ES517042A0 - Procedimiento para la preparacion de una aroilimidazolidin-2-ona. - Google Patents

Procedimiento para la preparacion de una aroilimidazolidin-2-ona.

Info

Publication number
ES517042A0
ES517042A0 ES517042A ES517042A ES517042A0 ES 517042 A0 ES517042 A0 ES 517042A0 ES 517042 A ES517042 A ES 517042A ES 517042 A ES517042 A ES 517042A ES 517042 A0 ES517042 A0 ES 517042A0
Authority
ES
Spain
Prior art keywords
alkyl
piperazino
hydrogen
lower alkyl
aroilimidazolidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES517042A
Other languages
English (en)
Other versions
ES8405374A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of ES517042A0 publication Critical patent/ES517042A0/es
Publication of ES8405374A1 publication Critical patent/ES8405374A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Fats And Perfumes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Supplying Of Containers To The Packaging Station (AREA)
ES517042A 1981-11-04 1982-11-02 Procedimiento para la preparacion de una aroilimidazolidin-2-ona. Expired ES8405374A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/317,963 US4410540A (en) 1981-11-04 1981-11-04 Cardiotonic 4-aroylimidazolidin-2-ones

Publications (2)

Publication Number Publication Date
ES517042A0 true ES517042A0 (es) 1984-06-16
ES8405374A1 ES8405374A1 (es) 1984-06-16

Family

ID=23236021

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517042A Expired ES8405374A1 (es) 1981-11-04 1982-11-02 Procedimiento para la preparacion de una aroilimidazolidin-2-ona.

Country Status (18)

Country Link
US (1) US4410540A (es)
EP (1) EP0079050B1 (es)
JP (1) JPS5885865A (es)
KR (1) KR880002708B1 (es)
AT (1) ATE26443T1 (es)
AU (1) AU552310B2 (es)
CA (1) CA1175829A (es)
DE (1) DE3275995D1 (es)
DK (1) DK488482A (es)
ES (1) ES8405374A1 (es)
GB (1) GB2110669B (es)
GR (1) GR77375B (es)
IE (1) IE54265B1 (es)
IL (1) IL67133A0 (es)
NO (1) NO823648L (es)
NZ (1) NZ202350A (es)
PH (1) PH19029A (es)
ZA (1) ZA827974B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709043A (en) * 1984-07-09 1987-11-24 Schering A.G. Process for the preparation of imidazolonecarbonylarylimidazoles
US4999365A (en) * 1987-03-20 1991-03-12 Merrell Dow Pharmaceuticals Inc. Method of reducing reperfusion injury with imidazol-2-thiones
JP2002505683A (ja) * 1997-06-18 2002-02-19 シナプティック・ファーマスーティカル・コーポレーション 複素環置換されたピペリジン類及びその使用
US6159990A (en) * 1997-06-18 2000-12-12 Synaptic Pharmaceutical Corporation Oxazolidinones as α1A receptor antagonists
US7091238B1 (en) 1999-06-21 2006-08-15 University Of Maryland Thienylhydrazon with digitalis-like properties (positive inotropic effects)
CA2384525C (en) * 1999-06-21 2007-03-06 University Of Maryland, Baltimore Thienylhydrazon with digitalis-like properties (positive inotropic effects)
ES2157822B1 (es) * 1999-08-17 2002-04-16 Kylolab S L Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1184709A (fr) * 1957-09-21 1959-07-24 Cfmc Nouveaux dérivés imidazoliques, utilisables comme agents de protection contre les rayons ultra-violets et leurs procédés de fabrication
US3337580A (en) * 1964-12-31 1967-08-22 Robins Co Inc A H 1-hydrocarbon-3 aryl-4-substituted ethyl-2-imidazolidinones
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones

Also Published As

Publication number Publication date
DK488482A (da) 1983-05-05
KR840002362A (ko) 1984-06-25
GR77375B (es) 1984-09-11
AU9011182A (en) 1983-05-12
NO823648L (no) 1983-05-05
NZ202350A (en) 1986-04-11
GB2110669B (en) 1985-04-11
CA1175829A (en) 1984-10-09
AU552310B2 (en) 1986-05-29
JPS5885865A (ja) 1983-05-23
KR880002708B1 (ko) 1988-12-26
DE3275995D1 (de) 1987-05-14
IE822621L (en) 1983-05-04
GB2110669A (en) 1983-06-22
IL67133A0 (en) 1983-03-31
IE54265B1 (en) 1989-08-02
JPH0435465B2 (es) 1992-06-11
ZA827974B (en) 1983-08-31
EP0079050B1 (en) 1987-04-08
PH19029A (en) 1985-12-06
ES8405374A1 (es) 1984-06-16
EP0079050A1 (en) 1983-05-18
ATE26443T1 (de) 1987-04-15
US4410540A (en) 1983-10-18

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970505