ES522867A0 - Procedimiento para la obtencion de azoles 2,4,5-trisustituidos. (como desglose y con prioridad de la patente espanola no.510.504, presentada el 17 de marzo de 1.982) - Google Patents

Procedimiento para la obtencion de azoles 2,4,5-trisustituidos. (como desglose y con prioridad de la patente espanola no.510.504, presentada el 17 de marzo de 1.982)

Info

Publication number
ES522867A0
ES522867A0 ES522867A ES522867A ES522867A0 ES 522867 A0 ES522867 A0 ES 522867A0 ES 522867 A ES522867 A ES 522867A ES 522867 A ES522867 A ES 522867A ES 522867 A0 ES522867 A0 ES 522867A0
Authority
ES
Spain
Prior art keywords
trisustituidos
azols
breakdown
march
priority
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES522867A
Other languages
English (en)
Other versions
ES8603498A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES522867A0 publication Critical patent/ES522867A0/es
Publication of ES8603498A1 publication Critical patent/ES8603498A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES522867A 1981-03-18 1983-05-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos. (como desglose y con prioridad de la patente espanola no.510.504, presentada el 17 de marzo de 1.982) Expired ES8603498A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH183881 1981-03-18

Publications (2)

Publication Number Publication Date
ES522867A0 true ES522867A0 (es) 1985-12-16
ES8603498A1 ES8603498A1 (es) 1985-12-16

Family

ID=4219779

Family Applications (8)

Application Number Title Priority Date Filing Date
ES510504A Granted ES510504A0 (es) 1981-03-18 1982-03-17 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos.
ES522867A Expired ES8603498A1 (es) 1981-03-18 1983-05-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos. (como desglose y con prioridad de la patente espanola no.510.504, presentada el 17 de marzo de 1.982)
ES522868A Expired ES8502980A1 (es) 1981-03-18 1983-05-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos. (como desglose y con prioridad de la patente espanola no.510.504, presentada el 17 de marzo de 1.982)
ES522869A Granted ES522869A0 (es) 1981-03-18 1983-05-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos. (como desglose y con prioridad de la patente espanola no.510.504, presentada el 17 de marzo de 1.982).
ES537277A Granted ES537277A0 (es) 1981-03-18 1984-10-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos.
ES537278A Granted ES537278A0 (es) 1981-03-18 1984-10-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos.
ES537343A Expired ES8601171A1 (es) 1981-03-18 1984-11-02 Procedimiento para la obtencion de azoles 2, 4, 5-trisustituidos
ES537342A Expired ES8604180A1 (es) 1981-03-18 1984-11-02 Procedimiento para la obtencion de azoles 2, 4, 5-trisustituidos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES510504A Granted ES510504A0 (es) 1981-03-18 1982-03-17 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos.

Family Applications After (6)

Application Number Title Priority Date Filing Date
ES522868A Expired ES8502980A1 (es) 1981-03-18 1983-05-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos. (como desglose y con prioridad de la patente espanola no.510.504, presentada el 17 de marzo de 1.982)
ES522869A Granted ES522869A0 (es) 1981-03-18 1983-05-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos. (como desglose y con prioridad de la patente espanola no.510.504, presentada el 17 de marzo de 1.982).
ES537277A Granted ES537277A0 (es) 1981-03-18 1984-10-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos.
ES537278A Granted ES537278A0 (es) 1981-03-18 1984-10-31 Procedimiento para la obtencion de azoles 2,4,5-trisustituidos.
ES537343A Expired ES8601171A1 (es) 1981-03-18 1984-11-02 Procedimiento para la obtencion de azoles 2, 4, 5-trisustituidos
ES537342A Expired ES8604180A1 (es) 1981-03-18 1984-11-02 Procedimiento para la obtencion de azoles 2, 4, 5-trisustituidos

Country Status (16)

Country Link
US (1) US4451471A (es)
EP (1) EP0061425A3 (es)
JP (1) JPS57183767A (es)
KR (1) KR830009066A (es)
AU (1) AU8166782A (es)
DK (1) DK118482A (es)
ES (8) ES510504A0 (es)
FI (1) FI820877L (es)
GB (1) GB2098203B (es)
GR (1) GR78347B (es)
HU (1) HU187684B (es)
IL (1) IL65285A (es)
NO (1) NO820881L (es)
NZ (1) NZ200038A (es)
PT (1) PT74593B (es)
ZA (1) ZA821790B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632930A (en) * 1984-11-30 1986-12-30 E. I. Du Pont De Nemours And Company Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives
DE3508665A1 (de) * 1985-03-12 1986-09-18 Hoechst Ag, 6230 Frankfurt Heterocyclische sulfide und ihre anwendung als immunmodulatoren
DE3508666A1 (de) * 1985-03-12 1986-09-18 Hoechst Ag, 6230 Frankfurt Heterocyclische disulfide und ihre anwendung als immunmodulatoren
JPS6339868A (ja) * 1986-08-04 1988-02-20 Otsuka Pharmaceut Factory Inc ジ低級アルキルフエノ−ル誘導体
ATE65082T1 (de) * 1987-07-27 1991-07-15 Duphar Int Res Thiazol-verbindungen mit fungizider aktivitaet.
AT392788B (de) * 1988-02-03 1991-06-10 Fisons Plc Neue benzimidazolverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
DE3807232A1 (de) * 1988-03-05 1989-09-14 Bayer Ag Substituierte acrylsaeureester
JP2933739B2 (ja) * 1990-04-09 1999-08-16 明治製菓株式会社 チアゾールまたはイミダゾール誘導体および抗潰瘍剤
US5255697A (en) * 1991-10-23 1993-10-26 Working Inc. Walking support apparatus
KR100342761B1 (ko) * 1994-03-08 2002-12-06 와이어쓰 항과혈당제로서의 티아졸리딘디온 유도체
JP2636819B2 (ja) 1994-12-20 1997-07-30 日本たばこ産業株式会社 オキサゾール系複素環式芳香族化合物
EP1205478A4 (en) * 1999-08-06 2004-06-30 Takeda Chemical Industries Ltd P38MAP KINASE INHIBITORS
MY149143A (en) * 2006-01-18 2013-07-15 Amgen Inc Thiazole compounds as protien kinase b (pkb) inhibitors
AU2008276512A1 (en) * 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of PKB
RU2638537C2 (ru) 2012-07-12 2017-12-14 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Ингибирование ферментов

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2129012A1 (de) * 1971-06-11 1973-01-04 Merck Patent Gmbh Azol-derivate
FR2146161A1 (en) * 1971-07-22 1973-03-02 Roussel Uclaf Thiazolyl thiolacetic acids - analgesics antiinflammatories and antipyretics
US3888870A (en) * 1974-03-08 1975-06-10 Sandoz Ag 2-sulfinyl-thiazoles and oxazoles
US4022607A (en) * 1975-06-09 1977-05-10 Sandoz, Inc. Substituted oxazoles and thiazoles as herbicides

Also Published As

Publication number Publication date
US4451471A (en) 1984-05-29
ES522868A0 (es) 1985-02-01
EP0061425A2 (de) 1982-09-29
ES8603499A1 (es) 1985-12-16
PT74593B (de) 1984-11-27
ES8604180A1 (es) 1986-01-16
ES537343A0 (es) 1985-10-16
IL65285A0 (en) 1982-05-31
FI820877A7 (fi) 1982-09-19
FI820877L (fi) 1982-09-19
ES8603498A1 (es) 1985-12-16
ZA821790B (en) 1983-01-26
ES8503677A1 (es) 1985-03-16
ES8601171A1 (es) 1985-10-16
ES8603847A1 (es) 1986-01-01
EP0061425A3 (de) 1982-12-15
NO820881L (no) 1982-09-20
IL65285A (en) 1985-11-29
ES8400102A1 (es) 1983-10-16
DK118482A (da) 1982-09-19
ES522869A0 (es) 1985-03-16
ES537342A0 (es) 1986-01-16
KR830009066A (ko) 1983-12-17
GB2098203B (en) 1985-05-09
PT74593A (de) 1982-04-01
ES8502980A1 (es) 1985-02-01
GB2098203A (en) 1982-11-17
AU8166782A (en) 1982-09-23
ES537278A0 (es) 1985-12-16
NZ200038A (en) 1985-05-31
GR78347B (es) 1984-09-26
ES537277A0 (es) 1986-01-01
JPS57183767A (en) 1982-11-12
HU187684B (en) 1986-02-28
ES510504A0 (es) 1983-10-16

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