ES523191A0 - Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas - Google Patents

Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas

Info

Publication number: ES523191A0
Authority: ES; Spain
Prior art keywords: sub; hydrogen; lower alkyl; benzazepines; tetrahydro
Prior art date: 1982-06-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES523191A

Other languages

English (en)

Other versions

ES8503666A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aventis Pharmaceuticals Inc

Original Assignee

Hoechst Roussel Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-06-14

Filing date

1983-06-13

Publication date

1985-03-01

1983-06-13 Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc

1985-03-01 Publication of ES523191A0 publication Critical patent/ES523191A0/es

1985-03-01 Publication of ES8503666A1 publication Critical patent/ES8503666A1/es

Status Expired legal-status Critical Current

Links

125000000217 alkyl group Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical group 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
-1 alkylene amine Chemical class 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

ES523191A 1982-06-14 1983-06-13 Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas Expired ES8503666A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/387,916 US4988690A (en)	1982-06-14	1982-06-14	1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant use thereof

Publications (2)

Publication Number	Publication Date
ES523191A0 true ES523191A0 (es)	1985-03-01
ES8503666A1 ES8503666A1 (es)	1985-03-01

Family

ID=23531838

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES523191A Expired ES8503666A1 (es)	1982-06-14	1983-06-13	Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas

Country Status (17)

Country	Link
US (1)	US4988690A (es)
EP (1)	EP0096838B1 (es)
JP (1)	JPS595165A (es)
KR (1)	KR900001214B1 (es)
AT (1)	ATE26263T1 (es)
AU (1)	AU570920B2 (es)
CA (1)	CA1214460A (es)
DE (1)	DE3370621D1 (es)
DK (1)	DK270983A (es)
ES (1)	ES8503666A1 (es)
FI (1)	FI78473C (es)
GR (1)	GR78291B (es)
HU (1)	HU190902B (es)
IE (1)	IE55404B1 (es)
IL (1)	IL68964A (es)
PT (1)	PT76864B (es)
ZA (1)	ZA834309B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA882080B (en) *	1987-03-27	1989-04-26	Schering Corp	Substituted benzazepines,their preparation and pharmaceutical compositions containing them
US5015639A (en) *	1987-03-27	1991-05-14	Schering Corporation	Substituted benzazepines, their preparation and pharmaceutical compositions containing them
CA1327795C (en) *	1987-08-14	1994-03-15	Jules Freedman	Antidepressants which are aryloxy inadanamines
US5202319A (en) *	1991-09-23	1993-04-13	Hoechst-Roussel Pharmaceuticals Inc.	Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines
US5639482A (en) *	1993-11-10	1997-06-17	Crary; Ely J.	Composition for control and prevention of diabetic retinopathy
WO2002044144A2 (en) *	2000-11-30	2002-06-06	Advanced Research And Technology Institute, Inc.	Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds
US6953787B2 (en) *	2002-04-12	2005-10-11	Arena Pharmaceuticals, Inc.	5HT2C receptor modulators
CN1805938B (zh) *	2003-06-17	2010-06-16	艾尼纳制药公司	用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
PL2332921T3 (pl) *	2003-06-17	2016-08-31	Arena Pharm Inc	Chlorowodorek 8-chloro-1-metylo-2,3,4,5-tetrahydro-1H-3-benzazepiny
US20080009478A1 (en) *	2003-10-22	2008-01-10	Arena Pharmaceuticals, Inc.	Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2c Receptor Associated Diseases
WO2005042490A1 (en) *	2003-10-22	2005-05-12	Arena Pharmaceuticals, Inc.	Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
NZ555981A (en)	2004-12-21	2011-01-28	Arena Pharm Inc	Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
BRPI0515862A2 (pt)	2004-12-23	2011-10-11	Arena Pharm Inc	uso de fentermina e agonista seletivo do receptor de 5ht-2c na preparação de composições, composições moduladoras do receptor de 5ht-2c e forma de dosagem unitária compreendendo as mesmas
EP2001852A2 (en)	2006-04-03	2008-12-17	Arena Pharmaceuticals, Inc.	Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
CN101547892B (zh) *	2006-12-05	2014-08-20	艾尼纳制药公司	制备(r)-8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的方法和其中间体
NZ580802A (en)	2007-05-10	2012-09-28	Albany Molecular Res Inc	Aryloxy-and heteroaryloxy-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
EP2288585A1 (en)	2008-03-04	2011-03-02	Arena Pharmaceuticals, Inc.	Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
US8952197B2 (en)	2009-06-18	2015-02-10	Arena Pharmaceuticals, Inc.	Processes for the preparation of 5-HT2C receptor agonists
US9045431B2 (en)	2010-06-02	2015-06-02	Arena Pharmaceuticals, Inc.	Processes for the preparation of 5-HT2C receptor agonists
AU2011296015B2 (en)	2010-09-01	2015-11-12	Arena Pharmaceuticals, Inc.	Administration of lorcaserin to individuals with renal impairment
JP6272695B2 (ja)	2010-09-01	2018-01-31	エーザイ・アール・アンド・ディー・マネジメント株式会社	体重管理のために有用な５−ｈｔ２ｃアゴニストの改変放出剤形
JP2013536859A (ja)	2010-09-01	2013-09-26	アリーナファーマシューティカルズ，インコーポレイテッド	５−ｈｔ２ｃアゴニストの非吸湿性塩
KR20130138770A (ko)	2010-09-01	2013-12-19	아레나 파마슈티칼스, 인크.	광학적으로 활성 산을 갖는 로르카세린의 염
JP2015534563A (ja)	2012-10-09	2015-12-03	アリーナファーマシューティカルズ，インコーポレイテッド	体重管理の方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5233687A (en) *	1975-09-11	1977-03-14	Shionogi & Co Ltd	Process for preparation of 1,5-dihydro-2h-1,4-benzodiazepine-2-on deri vatives
JPS5481290A (en) *	1977-11-17	1979-06-28	Smithkline Corp	Benzazepin compound

1982
- 1982-06-14 US US06/387,916 patent/US4988690A/en not_active Expired - Fee Related
1983
- 1983-06-08 DE DE8383105610T patent/DE3370621D1/de not_active Expired
- 1983-06-08 EP EP83105610A patent/EP0096838B1/en not_active Expired
- 1983-06-08 AT AT83105610T patent/ATE26263T1/de not_active IP Right Cessation
- 1983-06-10 FI FI832092A patent/FI78473C/fi not_active IP Right Cessation
- 1983-06-11 KR KR1019830002597A patent/KR900001214B1/ko not_active Expired
- 1983-06-13 ES ES523191A patent/ES8503666A1/es not_active Expired
- 1983-06-13 ZA ZA834309A patent/ZA834309B/xx unknown
- 1983-06-13 IL IL68964A patent/IL68964A/xx unknown
- 1983-06-13 CA CA000430280A patent/CA1214460A/en not_active Expired
- 1983-06-13 IE IE1384/83A patent/IE55404B1/en unknown
- 1983-06-13 HU HU832096A patent/HU190902B/hu not_active IP Right Cessation
- 1983-06-13 GR GR71648A patent/GR78291B/el unknown
- 1983-06-13 JP JP58104343A patent/JPS595165A/ja active Granted
- 1983-06-13 DK DK270983A patent/DK270983A/da not_active Application Discontinuation
- 1983-06-14 PT PT76864A patent/PT76864B/pt unknown
- 1983-06-14 AU AU15764/83A patent/AU570920B2/en not_active Ceased

Also Published As

Publication number	Publication date
CA1214460A (en)	1986-11-25
US4988690A (en)	1991-01-29
FI78473B (fi)	1989-04-28
HU190902B (en)	1986-12-28
AU1576483A (en)	1983-12-22
EP0096838A1 (en)	1983-12-28
IL68964A0 (en)	1983-10-31
AU570920B2 (en)	1988-03-31
PT76864B (en)	1986-02-27
DK270983D0 (da)	1983-06-13
IL68964A (en)	1988-03-31
ES8503666A1 (es)	1985-03-01
PT76864A (en)	1983-07-01
GR78291B (es)	1984-09-26
DE3370621D1 (en)	1987-05-07
KR840005103A (ko)	1984-11-03
JPH0365342B2 (es)	1991-10-11
IE55404B1 (en)	1990-09-12
IE831384L (en)	1983-12-14
FI78473C (fi)	1989-08-10
EP0096838B1 (en)	1987-04-01
ATE26263T1 (de)	1987-04-15
KR900001214B1 (ko)	1990-02-28
FI832092A0 (fi)	1983-06-10
DK270983A (da)	1983-12-15
FI832092L (fi)	1983-12-15
ZA834309B (en)	1984-03-28
JPS595165A (ja)	1984-01-12

Publication	Publication Date	Title
ES523191A0 (es)	1985-03-01	Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas
ATE37179T1 (de)	1988-09-15	Dihydropyridazinone.
MY109937A (en)	1997-10-31	Substituted azoles, processes for the preparation thereof, agents containing these, and the use thereof.
EP0202577A3 (en)	1989-08-02	N(acyldipeptidyl)-aminoglycols
ES8401961A1 (es)	1984-01-01	Procedimiento para la preparacion de nuevas n-(4-indolil-piperidino-alcohil-bencimidazolonas sustituidas.
GR3004250T3 (es)	1993-03-31
ES8602739A1 (es)	1985-12-16	Procedimiento para la fabricacion de nuevos derivados de la cumarina
ES8802152A1 (es)	1988-04-01	Procedimiento para preparar un derivado de 1,3-oxazolidina-2-ona.
ES8601201A1 (es)	1985-10-16	Procedimiento para preparar derivados de imidazolina
ZA816259B (en)	1983-04-27	2-(1,4-benzodioxan-2-ylalkyl)imidazoles useful as antidepressants
ES550003A0 (es)	1986-12-01	Procedimiento para preparar imidazo (1,2-c)pirimidinas
ES8604218A1 (es)	1986-01-16	Un procedimiento para la preparacion de benzoquinolicinas
ES527739A0 (es)	1985-04-16	Un procedimiento para preparar derivados de pirimidina
ES8504180A1 (es)	1985-04-01	Procedimiento para preparar nuevos derivados de piperidina
PL246418A1 (en)	1985-07-02	Process for preparing n-/3-trifluoromethylphenyl/-n'-propargylpiperazine
ATE30323T1 (de)	1987-11-15	5-phenylaethenylbenzimidazole.
GR880100112A (en)	1988-12-16	Method of preparation of new acetamide deravatives of dihydro-2,3 phenyl-3 benzophouranone-2
ES553600A0 (es)	1987-06-16	Un procedimiento para la preparacion de nuevos derivados de diamina.
PT73527B (en)	1982-11-03	Process for the preparation of n-sulphenylated ureas having fungicidal effect
JPS5636414A (en)	1981-04-09	Anticonvulsant agent containing omega-aminoalkoxystilbene or its acid addition salt as active constituent
KR880002858A (ko)	1988-05-12	퀴날딘 아미드 유도체의 제조방법