ES526397A0 - A PROCEDURE FOR THE PREPARATION OF NEW CEPHALOSPORIN DERIVATIVES - Google Patents

A PROCEDURE FOR THE PREPARATION OF NEW CEPHALOSPORIN DERIVATIVES

Info

Publication number
ES526397A0
ES526397A0 ES526397A ES526397A ES526397A0 ES 526397 A0 ES526397 A0 ES 526397A0 ES 526397 A ES526397 A ES 526397A ES 526397 A ES526397 A ES 526397A ES 526397 A0 ES526397 A0 ES 526397A0
Authority
ES
Spain
Prior art keywords
procedure
preparation
cephalosporin derivatives
new cephalosporin
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES526397A
Other languages
Spanish (es)
Other versions
ES8507557A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/354,851 external-priority patent/US4406899A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES526397A0 publication Critical patent/ES526397A0/en
Publication of ES8507557A1 publication Critical patent/ES8507557A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES526397A 1982-03-04 1983-10-11 Cephalosporin derivatives Expired ES8507557A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/354,851 US4406899A (en) 1982-03-04 1982-03-04 Cephalosporins
US35753482A 1982-03-12 1982-03-12

Publications (2)

Publication Number Publication Date
ES526397A0 true ES526397A0 (en) 1985-09-16
ES8507557A1 ES8507557A1 (en) 1985-09-16

Family

ID=26998584

Family Applications (2)

Application Number Title Priority Date Filing Date
ES520224A Expired ES8403919A1 (en) 1982-03-04 1983-03-02 Cephalosporin derivatives
ES526397A Expired ES8507557A1 (en) 1982-03-04 1983-10-11 Cephalosporin derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES520224A Expired ES8403919A1 (en) 1982-03-04 1983-03-02 Cephalosporin derivatives

Country Status (29)

Country Link
KR (1) KR870001986B1 (en)
AT (2) AT382155B (en)
AU (1) AU562776B2 (en)
BE (1) BE896086A (en)
CA (1) CA1213882A (en)
CH (1) CH654313A5 (en)
CS (1) CS249512B2 (en)
DD (1) DD210280A5 (en)
DE (1) DE3307550A1 (en)
DK (1) DK156900C (en)
EG (1) EG15934A (en)
ES (2) ES8403919A1 (en)
FI (1) FI74973C (en)
FR (1) FR2522659B1 (en)
GB (1) GB2116180B (en)
GR (1) GR77916B (en)
HU (1) HU193158B (en)
IE (1) IE56647B1 (en)
IL (1) IL68011A0 (en)
IT (1) IT1170307B (en)
LU (1) LU84674A1 (en)
MY (1) MY8700943A (en)
NL (2) NL193284C (en)
NZ (1) NZ203312A (en)
PH (1) PH18002A (en)
PT (1) PT76330B (en)
SE (1) SE453091B (en)
SU (1) SU1250173A3 (en)
YU (2) YU43822B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409431A1 (en) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE3404906A1 (en) * 1984-02-11 1985-08-14 Bayer Ag, 5090 Leverkusen 1-OXADETHIACEPHALOSPORINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
DE3419013A1 (en) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen NEW CEPHALOSPORINE AND METHOD FOR THEIR PRODUCTION
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
US4698336A (en) * 1985-01-30 1987-10-06 Eisai Co., Ltd. 3-(pyrrolidinio)methyl-3-cephem derivatives
FR2585705B1 (en) * 1985-08-05 1989-01-13 Bristol Myers Co CEPHALOSPORIN SALTS AND INJECTABLE COMPOSITIONS
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
DE3789466T2 (en) * 1986-03-17 1994-07-28 Fujisawa Pharmaceutical Co 3,7-disubstituted-3-cephem compounds and process for their preparation.
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
DE69231815T2 (en) 1991-03-08 2001-09-27 Biochemie Ges.M.B.H., Kundl Process for the preparation of cephalosporins and intermediates in this process
YU81692A (en) * 1991-09-10 1995-03-27 Bristol-Myers Co. PROCEDURE FOR THE PRODUCTION OF CEPHALOSPORIN ANTIBIOTICS
IL103110A (en) * 1991-09-10 1997-04-15 Bristol Myers Squibb Co Anhydrous process for preparing cefepime dihydrochloride hydrate
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
SI1699804T1 (en) * 2003-12-23 2008-08-31 Sandoz Ag Process for production of intermediates for use in cefalosporin synthesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2715385A1 (en) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd CEPHALOSPORIN DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THEM
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
AR228726A1 (en) * 1978-05-26 1983-04-15 Glaxo Group Ltd PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC (6R, 7R) -7 - ((Z) -2- (2-AMINOTIAZOL-4-IL) -2- (2-CARBOXIPROP-2-OXIIMINO) ACETAMIDO) -3- (1- PIRIDINIOMETIL) CEF-3-EM-4-CARBOXILATO
CH644867A5 (en) * 1978-10-27 1984-08-31 Glaxo Group Ltd CEPHEMIC CARBON ACIDS SUBSTITUTED IN THE 3- AND 7-POSITION.
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
NL990039I1 (en) 2000-01-03
LU84674A1 (en) 1983-11-17
DK156900C (en) 1990-03-12
IE56647B1 (en) 1991-10-23
FR2522659A1 (en) 1983-09-09
MY8700943A (en) 1987-12-31
GR77916B (en) 1984-09-25
NL990039I2 (en) 2000-04-03
SU1250173A3 (en) 1986-08-07
GB2116180A (en) 1983-09-21
IT1170307B (en) 1987-06-03
IT8347826A0 (en) 1983-03-01
KR870001986B1 (en) 1987-10-24
NL8300755A (en) 1983-10-03
PT76330B (en) 1986-02-04
FR2522659B1 (en) 1986-10-24
GB8305940D0 (en) 1983-04-07
CH654313A5 (en) 1986-02-14
DE3307550C2 (en) 1988-11-24
YU44777B (en) 1991-02-28
ES520224A0 (en) 1984-04-01
ATA76183A (en) 1986-06-15
ES8403919A1 (en) 1984-04-01
YU43822B (en) 1989-12-31
AT384612B (en) 1987-12-10
PH18002A (en) 1985-02-28
GB2116180B (en) 1985-09-18
SE8301178L (en) 1983-09-05
AT382155B (en) 1987-01-26
IE830455L (en) 1983-09-04
ATA228285A (en) 1987-05-15
YU52383A (en) 1986-02-28
DK86283A (en) 1983-09-05
DD210280A5 (en) 1984-06-06
DE3307550A1 (en) 1983-09-15
SE453091B (en) 1988-01-11
DK86283D0 (en) 1983-02-24
EG15934A (en) 1987-10-30
ES8507557A1 (en) 1985-09-16
NL193284C (en) 1999-05-06
DK156900B (en) 1989-10-16
CA1213882A (en) 1986-11-12
HU193158B (en) 1987-08-28
FI830689A0 (en) 1983-03-01
FI74973B (en) 1987-12-31
NZ203312A (en) 1985-12-13
AU1130483A (en) 1983-09-08
SE8301178D0 (en) 1983-03-03
FI830689L (en) 1983-09-05
BE896086A (en) 1983-09-05
YU149685A (en) 1986-02-28
FI74973C (en) 1988-04-11
IL68011A0 (en) 1983-06-15
KR840004118A (en) 1984-10-06
CS249512B2 (en) 1987-03-12
PT76330A (en) 1983-04-01
NL193284B (en) 1999-01-04
AU562776B2 (en) 1987-06-18

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050601