ES531713A0 - Un metodo para preparar un agente explorador de huesos marcado con tecnecio-99m - Google Patents
Un metodo para preparar un agente explorador de huesos marcado con tecnecio-99mInfo
- Publication number
- ES531713A0 ES531713A0 ES531713A ES531713A ES531713A0 ES 531713 A0 ES531713 A0 ES 531713A0 ES 531713 A ES531713 A ES 531713A ES 531713 A ES531713 A ES 531713A ES 531713 A0 ES531713 A0 ES 531713A0
- Authority
- ES
- Spain
- Prior art keywords
- tecnetio
- exploring
- bone
- preparing
- agent marked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000000988 bone and bone Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838310438A GB8310438D0 (en) | 1983-04-18 | 1983-04-18 | Bone-seeking complexes of technetium-99m |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8506193A1 ES8506193A1 (es) | 1985-07-01 |
| ES531713A0 true ES531713A0 (es) | 1985-07-01 |
Family
ID=10541258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES531713A Granted ES531713A0 (es) | 1983-04-18 | 1984-04-17 | Un metodo para preparar un agente explorador de huesos marcado con tecnecio-99m |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4642229A (es) |
| EP (1) | EP0122813B1 (es) |
| JP (1) | JPS59205331A (es) |
| AU (1) | AU2704884A (es) |
| CA (1) | CA1213519A (es) |
| DE (1) | DE3472532D1 (es) |
| ES (1) | ES531713A0 (es) |
| GB (1) | GB8310438D0 (es) |
| NO (1) | NO841563L (es) |
| ZA (1) | ZA842888B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8521380D0 (en) * | 1985-08-28 | 1985-10-02 | Amersham Int Plc | Bone-seeking complexes of technetium-99m |
| GB8615916D0 (en) * | 1986-06-30 | 1986-08-06 | Amersham Int Plc | Bone-seeking complexes of technetium-99m |
| US5089249A (en) * | 1988-06-10 | 1992-02-18 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
| US5202109A (en) * | 1988-06-10 | 1993-04-13 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
| US5192526A (en) * | 1989-05-02 | 1993-03-09 | Mallinckrodt Medical, Inc. | Kit for preparation of rhenium therapeutic agents for bone cancer without purification |
| EP0692978A4 (en) * | 1993-03-31 | 1998-05-06 | Mallinckrodt Medical Inc | RADIOPHARMACEUTICAL PREPARATIONS THAT DO NOT CONTAIN TIN REDUCER |
| DE19804124A1 (de) * | 1998-02-03 | 1999-08-05 | Bayer Ag | Phosphorhaltige Verbindungen auf Basis der 1-Hydroxypropan-1,3-diphosphonsäure |
| GB0015242D0 (en) * | 2000-06-22 | 2000-08-16 | Nycomed Amersham Plc | Stabiliser for radiopharmaceuticals |
| US6436386B1 (en) | 2000-11-14 | 2002-08-20 | Shearwater Corporation | Hydroxyapatite-targeting poly (ethylene glycol) and related polymers |
| US7829074B2 (en) | 2001-10-18 | 2010-11-09 | Nektar Therapeutics | Hydroxypatite-targeting poly(ethylene glycol) and related polymers |
| TW200505934A (en) * | 2003-03-26 | 2005-02-16 | Nihon Mediphysics Co Ltd | Compound having affinity with calcified tissue |
| EP2214716B1 (en) | 2007-10-23 | 2021-11-17 | Nektar Therapeutics | Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom |
| WO2021032784A1 (en) | 2019-08-19 | 2021-02-25 | Nuclear Research And Consultancy Group | Platinum isotope combined with bone-targeting agents for use in anticancer drugs |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3983227A (en) * | 1973-05-23 | 1976-09-28 | The Procter & Gamble Company | Dry mixture containing diphosphonates and a stannous salt useful in the preparation of Tc99M containing bone scanning agents |
| US4088747A (en) * | 1975-02-19 | 1978-05-09 | Australian Atomic Energy Commission | Phenolic amino-carboxylic acid radiopharmaceuticals |
| CA1078731A (en) * | 1976-12-16 | 1980-06-03 | Charles E. Frosst And Co. | Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid) |
| US4247534A (en) * | 1978-07-31 | 1981-01-27 | The Procter & Gamble Company | Radiographic scanning agent |
| US4387087A (en) * | 1980-04-18 | 1983-06-07 | Research Corporation | Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging |
| US4515766A (en) * | 1980-06-23 | 1985-05-07 | The Massachusetts General Hospital | Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium |
-
1983
- 1983-04-18 GB GB838310438A patent/GB8310438D0/en active Pending
-
1984
- 1984-04-16 US US06/600,408 patent/US4642229A/en not_active Expired - Fee Related
- 1984-04-16 CA CA000452108A patent/CA1213519A/en not_active Expired
- 1984-04-17 NO NO841563A patent/NO841563L/no unknown
- 1984-04-17 ES ES531713A patent/ES531713A0/es active Granted
- 1984-04-17 JP JP59078284A patent/JPS59205331A/ja active Pending
- 1984-04-17 ZA ZA842888A patent/ZA842888B/xx unknown
- 1984-04-18 DE DE8484302647T patent/DE3472532D1/de not_active Expired
- 1984-04-18 EP EP84302647A patent/EP0122813B1/en not_active Expired
- 1984-04-18 AU AU27048/84A patent/AU2704884A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0122813B1 (en) | 1988-07-06 |
| NO841563L (no) | 1984-10-19 |
| CA1213519A (en) | 1986-11-04 |
| DE3472532D1 (en) | 1988-08-11 |
| GB8310438D0 (en) | 1983-05-25 |
| ES8506193A1 (es) | 1985-07-01 |
| US4642229A (en) | 1987-02-10 |
| JPS59205331A (ja) | 1984-11-20 |
| EP0122813A3 (en) | 1985-07-03 |
| ZA842888B (en) | 1985-01-30 |
| EP0122813A2 (en) | 1984-10-24 |
| AU2704884A (en) | 1984-10-25 |
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