ES535357A0 - Un metodo de preparar espiro-(benzofuran-azalcanos) - Google Patents
Un metodo de preparar espiro-(benzofuran-azalcanos)Info
- Publication number
- ES535357A0 ES535357A0 ES535357A ES535357A ES535357A0 ES 535357 A0 ES535357 A0 ES 535357A0 ES 535357 A ES535357 A ES 535357A ES 535357 A ES535357 A ES 535357A ES 535357 A0 ES535357 A0 ES 535357A0
- Authority
- ES
- Spain
- Prior art keywords
- azalcanos
- benzofuran
- preparing spiral
- spiral
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052736 halogen Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000003003 spiro group Chemical group 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/526,193 US4452802A (en) | 1983-08-25 | 1983-08-25 | Antihypertensive spiro[benzofuran-azalkanes] |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES535357A0 true ES535357A0 (es) | 1986-05-16 |
| ES8607313A1 ES8607313A1 (es) | 1986-05-16 |
Family
ID=24096310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES535357A Expired ES8607313A1 (es) | 1983-08-25 | 1984-08-23 | Un metodo de preparar espiro-(benzofuran-azalcanos) |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4452802A (es) |
| EP (1) | EP0139138B1 (es) |
| JP (1) | JPS6072892A (es) |
| AT (1) | ATE28200T1 (es) |
| DE (1) | DE3464609D1 (es) |
| DK (1) | DK405884A (es) |
| ES (1) | ES8607313A1 (es) |
| GR (1) | GR80173B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4788201A (en) * | 1987-01-22 | 1988-11-29 | Hoechst-Roussel Pharmaceuticals Inc. | 3-methylenespiro (benzofuranpiperidines) |
| IL96507A0 (en) * | 1989-12-08 | 1991-08-16 | Merck & Co Inc | Nitrogen-containing spirocycles and pharmaceutical compositions containing them |
| NZ243065A (en) | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| DK78692D0 (da) * | 1992-06-12 | 1992-06-12 | Lundbeck & Co As H | Dimere piperidin- og piperazinderivater |
| DE69412067T2 (de) * | 1993-01-28 | 1999-03-25 | Merck & Co., Inc., Rahway, N.J. | Substituierte spiro-azaringen als tachykinine rezeptor antagonisten |
| WO2007028638A1 (en) | 2005-09-09 | 2007-03-15 | Euro-Celtique S.A. | Fused and spirocycle compounds and the use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3962259A (en) * | 1973-12-12 | 1976-06-08 | American Hoechst Corporation | 1,3-Dihydrospiro[isobenzofuran]s and derivatives thereof |
| US4166120A (en) * | 1978-04-14 | 1979-08-28 | American Hoechst Corporation | Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines |
| US4166119A (en) * | 1978-04-14 | 1979-08-28 | American Hoechst Corporation | Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines |
-
1983
- 1983-08-25 US US06/526,193 patent/US4452802A/en not_active Expired - Fee Related
-
1984
- 1984-08-14 EP EP84109647A patent/EP0139138B1/en not_active Expired
- 1984-08-14 DE DE8484109647T patent/DE3464609D1/de not_active Expired
- 1984-08-14 AT AT84109647T patent/ATE28200T1/de not_active IP Right Cessation
- 1984-08-23 GR GR80173A patent/GR80173B/el unknown
- 1984-08-23 ES ES535357A patent/ES8607313A1/es not_active Expired
- 1984-08-24 DK DK405884A patent/DK405884A/da not_active Application Discontinuation
- 1984-08-24 JP JP59175334A patent/JPS6072892A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GR80173B (en) | 1985-01-02 |
| DK405884D0 (da) | 1984-08-24 |
| DE3464609D1 (en) | 1987-08-13 |
| ES8607313A1 (es) | 1986-05-16 |
| DK405884A (da) | 1985-02-26 |
| JPS6072892A (ja) | 1985-04-24 |
| EP0139138A1 (en) | 1985-05-02 |
| US4452802A (en) | 1984-06-05 |
| EP0139138B1 (en) | 1987-07-08 |
| ATE28200T1 (de) | 1987-07-15 |
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