ES537783A0 - Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos. - Google Patents

Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos.

Info

Publication number
ES537783A0
ES537783A0 ES537783A ES537783A ES537783A0 ES 537783 A0 ES537783 A0 ES 537783A0 ES 537783 A ES537783 A ES 537783A ES 537783 A ES537783 A ES 537783A ES 537783 A0 ES537783 A0 ES 537783A0
Authority
ES
Spain
Prior art keywords
dihidrobenzufuranos
analagos
hydroxy
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES537783A
Other languages
English (en)
Other versions
ES8602734A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES537783A0 publication Critical patent/ES537783A0/es
Publication of ES8602734A1 publication Critical patent/ES8602734A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Furan Compounds (AREA)
ES537783A 1983-11-21 1984-11-20 Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos. Expired ES8602734A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/553,668 US4563476A (en) 1983-11-21 1983-11-21 Substituted 5-hydroxy-2,3-dihydrobenzofurans and analogs thereof useful as anti-inflammatory agents

Publications (2)

Publication Number Publication Date
ES537783A0 true ES537783A0 (es) 1985-12-01
ES8602734A1 ES8602734A1 (es) 1985-12-01

Family

ID=24210278

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537783A Expired ES8602734A1 (es) 1983-11-21 1984-11-20 Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos.

Country Status (7)

Country Link
US (1) US4563476A (es)
EP (1) EP0150291B1 (es)
JP (1) JPS60149576A (es)
CA (1) CA1261333A (es)
DE (1) DE3477194D1 (es)
DK (1) DK549284A (es)
ES (1) ES8602734A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966907A (en) * 1988-08-12 1990-10-30 Merck & Co., Inc. 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis
US4975457A (en) * 1989-09-25 1990-12-04 Merck & Co., Inc. Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis
US5091533A (en) * 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
GB2262524A (en) * 1991-12-18 1993-06-23 Sandoz Ltd Pharmaceutically active 2-hydroxy-benzylamines
FR2720395B1 (fr) * 1994-05-31 1996-06-28 Oreal Nouveaux composés de la famille des benzohétérocycles.
US7504228B2 (en) * 2001-06-05 2009-03-17 Qlt Inc. Integrin linked kinase modulation of monocyte activation
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
TR201908314T4 (tr) 2009-02-20 2019-06-21 2 Bbb Medicines B V Glutatyon bazlı ilaç dağıtım sistemi.
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH567011A5 (es) * 1972-12-19 1975-09-30 Eisai Co Ltd
FR2244458A1 (en) * 1973-09-20 1975-04-18 Bottu Benzofuran derivs - useful as anti-inflammatories and analgesics
JPS5942300B2 (ja) * 1975-04-24 1984-10-13 富士写真フイルム株式会社 色画像耐光堅牢化方法
FR2353291A1 (fr) * 1976-05-31 1977-12-30 Parcor Nouveaux derives du benzofuranne
AU559687B2 (en) * 1981-07-01 1987-03-19 Upjohn Company, The Pyridinyl-and imidazolyl-benzofurane and benzothiophenes

Also Published As

Publication number Publication date
DK549284D0 (da) 1984-11-20
CA1261333A (en) 1989-09-26
DK549284A (da) 1985-07-03
ES8602734A1 (es) 1985-12-01
EP0150291A1 (en) 1985-08-07
US4563476A (en) 1986-01-07
JPS60149576A (ja) 1985-08-07
DE3477194D1 (en) 1989-04-20
EP0150291B1 (en) 1989-03-15

Similar Documents

Publication Publication Date Title
ES528628A0 (es) Un procedimiento para la preparacion de pirazolo y piridazo-pirazolinas, piridazinas y diazepinas.
ES533753A0 (es) Un procedimiento para la preparacion de nuevas fenoxialquil-1-2-4-triazolonas.
ES539625A0 (es) Un procedimiento para la preparacion de derivados de fenetano.
ES538256A0 (es) Un procedimiento para la preparacion de derivados de 2,2'-iminobisetanol.
ES533097A0 (es) Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
ES532582A0 (es) Un procedimiento para la preparacion de nuevos cromanos y cromenos.
ES524320A0 (es) Un procedimiento para la preparacion de 4-amino-6,7-dimetoxi quinoles.
ES540901A0 (es) Un procedimiento para la preparacion de derivados de n,n-pipericinilo disustituidos.
ES532591A0 (es) Un procedimiento para la preparacion de nuevos derivados de cromano.
ES534892A0 (es) Un procedimiento para la preparacion de derivados de penem-2-metil sustituidos.
ES534825A0 (es) Un procedimiento para la preparacion de nuevos antagonistas de leucotrieno.
ES536525A0 (es) Un procedimiento para la preparacion de derivados de fenotiazinas.
ES524271A0 (es) Un procedimiento para la preparacion de nuevos derivados de daunorrubicina y doxorrubicina.
ES535953A0 (es) Un procedimiento para la preparacion de derivados 3-cefem-4-carboxilicos.
ES530418A0 (es) Un procedimiento para la preparacion de pirazolopiridinas.
ES538907A0 (es) Un procedimiento para la preparacion de derivados enol-eteres de oxicanis.
ES541781A0 (es) Un procedimiento para la preparacion de nuevos benzotiopenos.
ES536683A0 (es) Un procedimiento para la preparacion de nuevos cinamil-2,3-dihidro-benzofuranos sustituidos y sus analagos.
ES529846A0 (es) Un procedimiento para la preparacion de derivados benzoheterociclicos.
ES537783A0 (es) Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos.
ES533390A0 (es) Un procedimiento para la preparacion de nuevos derivados de 2-sulfamoilbenzo (b) tiofeno.
ES533389A0 (es) Un procedimiento para la preparacion de nuevos derivados de tiosulfonamida.
ES547205A0 (es) Un procedimiento para la preparacion de nuevas quinazolindionas.
ES534642A0 (es) Un procedimiento para la preparacion de nuevos derivados de carbaciclina.
ES529213A0 (es) Un procedimiento para la preparacion de derivados de isoquinuclidina.