ES538423A0 - Un procedimiento para aislar vancomicina de una solucion acuosa - Google Patents

Un procedimiento para aislar vancomicina de una solucion acuosa

Info

Publication number: ES538423A0
Authority: ES; Spain
Prior art keywords: isolating; aqueous solution; vancomicin; procedure; vancomycin
Prior art date: 1983-12-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES538423A

Other languages

English (en)

Other versions

ES8606409A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-12

Filing date

1984-12-07

Publication date

1986-04-01

1984-12-07 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1986-04-01 Publication of ES538423A0 publication Critical patent/ES538423A0/es

1986-04-01 Publication of ES8606409A1 publication Critical patent/ES8606409A1/es

Status Expired legal-status Critical Current

Links

239000007864 aqueous solution Substances 0.000 title abstract 2
MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 title 1
108010059993 Vancomycin Proteins 0.000 abstract 4
229960003165 vancomycin Drugs 0.000 abstract 4
MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 abstract 4
MYPYJXKWCTUITO-LYRMYLQWSA-O vancomycin(1+) Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C([O-])=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)[NH2+]C)[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-O 0.000 abstract 3
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000001177 diphosphate Substances 0.000 abstract 1
XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 abstract 1
235000011180 diphosphates Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pyrane Compounds (AREA)
Compounds Of Unknown Constitution (AREA)
Cephalosporin Compounds (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ES538423A 1983-12-12 1984-12-07 Un procedimiento para aislar vancomicina de una solucion acuosa Expired ES8606409A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US56030083A	1983-12-12	1983-12-12

Publications (2)

Publication Number	Publication Date
ES538423A0 true ES538423A0 (es)	1986-04-01
ES8606409A1 ES8606409A1 (es)	1986-04-01

Family

ID=24237197

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES538423A Expired ES8606409A1 (es)	1983-12-12	1984-12-07	Un procedimiento para aislar vancomicina de una solucion acuosa
ES548042A Expired ES8607756A1 (es)	1983-12-12	1985-10-18	Un procedimiento para la preparacion de hidrocloruro de van-comicina

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES548042A Expired ES8607756A1 (es)	1983-12-12	1985-10-18	Un procedimiento para la preparacion de hidrocloruro de van-comicina

Country Status (21)

Country	Link
EP (1)	EP0145484B1 (es)
JP (1)	JPH0689038B2 (es)
KR (1)	KR870000550B1 (es)
AT (1)	ATE41015T1 (es)
AU (1)	AU575887B2 (es)
CA (1)	CA1245639A (es)
DE (1)	DE3476886D1 (es)
DK (1)	DK164914C (es)
EG (1)	EG16899A (es)
ES (2)	ES8606409A1 (es)
FI (1)	FI844801A7 (es)
GB (1)	GB2151234B (es)
GR (1)	GR81191B (es)
HU (1)	HU194914B (es)
IE (1)	IE57674B1 (es)
IL (1)	IL73746A (es)
NZ (1)	NZ210470A (es)
PH (1)	PH20269A (es)
PL (1)	PL250763A1 (es)
PT (1)	PT79634B (es)
ZA (1)	ZA849516B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4736031A (en) *	1985-06-10	1988-04-05	Takeda Chemical Industries, Ltd.	2-(piperazinylalkyl)-1-benzothiepin, 1-benzoxepin, and 1,5-benzodioxepin derivatives
GB8600952D0 (en) *	1986-01-16	1986-02-19	Glaxo Group Ltd	Antibiotic production
US4874843A (en) *	1987-12-03	1989-10-17	Eli Lilly And Company	Chromatographic purification process
CA1320312C (en) *	1987-12-28	1993-07-13	Harold Raymond Catt	Improved vancomycin precipitation process
US5037652A (en) *	1987-12-28	1991-08-06	Eli Lilly And Company	Vancomycin precipitation process
US5574135A (en) *	1990-07-10	1996-11-12	Abbott Laboratories	Process for making vancomycin
US5149784A (en) *	1990-07-10	1992-09-22	Abbott Laboratories	Process for making vancomycin
US5258495A (en) *	1990-07-10	1993-11-02	Abbott Laboratories	Process for making vancomycin HC1
US5235037A (en) *	1991-08-15	1993-08-10	American Cyanamid Company	Vancomycin precipitation process
KR19980039737A (ko) *	1996-11-28	1998-08-17	손경식	반코마이신의 결정화방법
SI21924A (sl) *	2004-12-07	2006-06-30	Lek Farmacevtska Druzba D.D.	Cist vankomicin hidroklorid
EP1798237A1 (en) *	2005-12-16	2007-06-20	Pharmatex Italia Srl	Process for the purification of macrolide antibiotics
EP2097440A4 (en) *	2006-12-22	2010-09-08	Targanta Therapeutics Inc	ANTIBIOTICS BASED ON GLYCOPEPTIDES AND LIPOGLYCOPEPTIDES PHOSPHONES AND THEIR USES IN THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS
JP2011153119A (ja) *	2010-01-27	2011-08-11	Mylan Seiyaku Ltd	バンコマイシンまたはその塩を含有する錠剤
CN104672310A (zh) *	2013-11-27	2015-06-03	北大医药重庆大新药业股份有限公司	一种盐酸万古霉素的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3067099A (en) *	1955-09-16	1962-12-04	Lilly Co Eli	Vancomycin and method for its preparation
US4667024A (en) *	1983-07-13	1987-05-19	Smithkline Beckman Corporation	Process for the preparation of purified vancomycin class antibiotics

1984
- 1984-12-05 IL IL73746A patent/IL73746A/xx not_active IP Right Cessation
- 1984-12-05 FI FI844801A patent/FI844801A7/fi not_active Application Discontinuation
- 1984-12-05 CA CA000469358A patent/CA1245639A/en not_active Expired
- 1984-12-05 GR GR81191A patent/GR81191B/el unknown
- 1984-12-05 JP JP59258386A patent/JPH0689038B2/ja not_active Expired - Lifetime
- 1984-12-06 PL PL25076384A patent/PL250763A1/xx unknown
- 1984-12-06 PT PT79634A patent/PT79634B/pt unknown
- 1984-12-06 ZA ZA849516A patent/ZA849516B/xx unknown
- 1984-12-06 NZ NZ210470A patent/NZ210470A/en unknown
- 1984-12-06 PH PH31539A patent/PH20269A/en unknown
- 1984-12-07 ES ES538423A patent/ES8606409A1/es not_active Expired
- 1984-12-10 DK DK589484A patent/DK164914C/da not_active IP Right Cessation
- 1984-12-11 EP EP84308610A patent/EP0145484B1/en not_active Expired
- 1984-12-11 DE DE8484308610T patent/DE3476886D1/de not_active Expired
- 1984-12-11 AT AT84308610T patent/ATE41015T1/de not_active IP Right Cessation
- 1984-12-11 GB GB08431231A patent/GB2151234B/en not_active Expired
- 1984-12-11 EG EG759/84A patent/EG16899A/xx active
- 1984-12-11 AU AU36480/84A patent/AU575887B2/en not_active Expired
- 1984-12-11 HU HU844603A patent/HU194914B/hu unknown
- 1984-12-11 IE IE3179/84A patent/IE57674B1/en not_active IP Right Cessation
- 1984-12-12 KR KR1019840007851A patent/KR870000550B1/ko not_active Expired
1985
- 1985-10-18 ES ES548042A patent/ES8607756A1/es not_active Expired

Also Published As

Publication number	Publication date
PL250763A1 (en)	1985-07-02
HU194914B (en)	1988-03-28
EP0145484A2 (en)	1985-06-19
EG16899A (en)	1992-06-30
DK164914C (da)	1993-02-01
IL73746A0 (en)	1985-03-31
FI844801L (fi)	1985-06-13
CA1262800C (es)	1989-11-07
AU3648084A (en)	1985-06-20
ES8607756A1 (es)	1986-06-01
HUT36835A (en)	1985-10-28
KR870000550B1 (ko)	1987-03-18
IL73746A (en)	1988-07-31
JPH0689038B2 (ja)	1994-11-09
GR81191B (en)	1985-04-08
FI844801A0 (fi)	1984-12-05
GB2151234B (en)	1987-07-29
PH20269A (en)	1986-11-14
ES548042A0 (es)	1986-06-01
PT79634A (en)	1985-01-01
JPS60139623A (ja)	1985-07-24
EP0145484A3 (en)	1986-06-04
FI844801A7 (fi)	1985-06-13
GB2151234A (en)	1985-07-17
GB8431231D0 (en)	1985-01-23
ZA849516B (en)	1986-07-30
DK589484A (da)	1985-06-13
NZ210470A (en)	1987-03-31
KR850004266A (ko)	1985-07-11
PT79634B (en)	1986-12-22
AU575887B2 (en)	1988-08-11
DK164914B (da)	1992-09-07
ES8606409A1 (es)	1986-04-01
IE843179L (en)	1985-06-12
DE3476886D1 (en)	1989-04-06
IE57674B1 (en)	1993-02-24
DK589484D0 (da)	1984-12-10
ATE41015T1 (de)	1989-03-15
CA1245639A (en)	1988-11-29
EP0145484B1 (en)	1989-03-01

Legal Events

Date	Code	Title	Description
2007-04-01	FD1A	Patent lapsed	Effective date: 20051114

Publication	Publication Date	Title
AU575887B2 (en)	1988-08-11	Crystalline vancomygin salts
ATE48278T1 (de)	1989-12-15	Verfahren zur herstellung von 2'desoxyadenosinverbindungen.
BR8108346A (pt)	1982-10-13	Processo para preparacao enzimatica de acido l-2-amino-4-metil-fosfinobutirico
BR7605323A (pt)	1977-08-09	Processo para a preparacao de solucoes de fosfato alcalino de elevado grau de pureza a partir de acido fosforico de processo a umido
YU20583A (en)	1986-02-28	Process for the purification of phosphoric acid obtained by the wet method starting from phosphates
DE3777611D1 (de)	1992-04-23	Lysozyme hydrochlorid und dikaliumglycyrrhizinat enthaltende loesung.
BR8300111A (pt)	1983-10-04	Processo para a producao de acido fosforico;processo para enriquecer minerio de fosfato
HUT36797A (en)	1985-10-28	Process for producing monosodium salt of 7-d-mandelamido-3-/1-sulfomethyl-tetrazol-5-y1-thio-methyl/-3-cepheme-4-carboxylic acid
DE3160219D1 (en)	1983-06-09	Process for treating an aqueous alcaline solution of anthraquinone-disulfonic acid salts
BR7501597A (pt)	1975-12-16	Processo para a producao de acido fosforico contendo fosfatos de calcio
JPS5728070A (en)	1982-02-15	Monosodium salt dihydrate of 1,2,3-triazole-5-thiol and its preparation
ATE24515T1 (de)	1987-01-15	Verfahren zur herstellung von hochkristallinem cefoperazon-natrium.
HU175141B (hu)	1980-05-28	Sposob poluchenija ingredienta tipa slozhnogo alkoksi-alkil-ehfira fosfornoj kisloty dlja modifikacii naleganija