ES545560A0 - Nuevos esteres de 9 -fluoro- o cloro- corticoesteroides y procedimiento para sus producciones - Google Patents

Nuevos esteres de 9 -fluoro- o cloro- corticoesteroides y procedimiento para sus producciones

Info

Publication number
ES545560A0
ES545560A0 ES545560A ES545560A ES545560A0 ES 545560 A0 ES545560 A0 ES 545560A0 ES 545560 A ES545560 A ES 545560A ES 545560 A ES545560 A ES 545560A ES 545560 A0 ES545560 A0 ES 545560A0
Authority
ES
Spain
Prior art keywords
sub
chlorine
fluorine
esters
corticoesteroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES545560A
Other languages
English (en)
Other versions
ES8606878A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hovione Inter AG
Original Assignee
Hovione Inter AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Inter AG filed Critical Hovione Inter AG
Publication of ES8606878A1 publication Critical patent/ES8606878A1/es
Publication of ES545560A0 publication Critical patent/ES545560A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
ES545560A 1984-07-25 1985-07-24 Nuevos esteres de 9 -fluoro- o cloro- corticoesteroides y procedimiento para sus producciones Expired ES8606878A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT78973A PT78973A (en) 1984-07-25 1984-07-25 New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid

Publications (2)

Publication Number Publication Date
ES8606878A1 ES8606878A1 (es) 1986-06-01
ES545560A0 true ES545560A0 (es) 1986-06-01

Family

ID=20083528

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545560A Expired ES8606878A1 (es) 1984-07-25 1985-07-24 Nuevos esteres de 9 -fluoro- o cloro- corticoesteroides y procedimiento para sus producciones

Country Status (16)

Country Link
US (1) US5026693A (es)
EP (1) EP0170500B1 (es)
JP (2) JPS6153297A (es)
KR (1) KR880001238B1 (es)
AT (1) ATE57384T1 (es)
AU (1) AU571986B2 (es)
CA (1) CA1307257C (es)
DE (1) DE3580072D1 (es)
DK (1) DK167617B1 (es)
ES (1) ES8606878A1 (es)
HK (1) HK107990A (es)
IE (1) IE58941B1 (es)
IL (1) IL75871A (es)
NZ (1) NZ212876A (es)
PT (1) PT78973A (es)
ZA (1) ZA855621B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4333920A1 (de) 1993-10-05 1995-04-13 Hoechst Ag Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
JP7106773B1 (ja) * 2022-01-25 2022-07-26 同仁医薬化工株式会社 ステロイド１７α，２１－ジエステル類の製造方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE634881A (es) * 1963-01-21
GB1047519A (en) * 1963-06-11 1966-11-02 Glaxo Lab Ltd 17ª‡,21-diesters of 11,17,21-trihydroxy steroid compounds
GB1047518A (en) * 1963-06-11 1966-11-02 Glaxo Lab Ltd 17ª‡-monoesters of 11,17,21-trihydroxy steroid compounds
US3876633A (en) * 1973-02-21 1975-04-08 Omni Research Processes and intermediates for 16-substituted corticoid synthesis
JPS5710417Y2 (es) * 1973-08-07 1982-03-01
AT357696B (de) * 1974-03-27 1980-07-25 Plurichemie Anstalt Verfahren zur herstellung von 16alpha- und 16beta-methyl-9alpha-chlor- oder -fluor-21- -desoxyprednisolonestern und -aethern
ZA751599B (en) * 1974-03-27 1976-02-25 Plurichemie Anstalt 16-methyl-9alpha-halo steroid esters, ethers and preparation thereof
DE2512915A1 (de) * 1974-03-27 1975-10-09 Plurichemie Anstalt 16-methyl-9 alpha-halogen-steroide ester, aether und verfahren zu ihrer herstellung
YU54476A (en) * 1975-03-31 1982-05-31 Taisho Pharmaceutical Co Ltd Process for obtaining 17-ester 21-halo-pregnane
CH626632A5 (en) * 1975-12-12 1981-11-30 Ciba Geigy Ag Process for the preparation of halopregnadienes
JPS5276675A (en) * 1975-12-23 1977-06-28 Seikosha Kk Method of manufacturing electrodes
DE2617655C2 (de) * 1976-04-21 1984-11-08 F. Hoffmann-La Roche & Co Ag, Basel Kortikoide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
JPS5820157B2 (ja) * 1978-02-03 1983-04-21 アルプス電気株式会社 回路板の形成方法
JPS54144823A (en) * 1978-05-04 1979-11-12 Nippon Telegr & Teleph Corp <Ntt> Keyboard of non-keying type
JPS55115216A (en) * 1979-02-27 1980-09-05 Fujitsu Ltd Method of forming movable electrode on base
DE3071122D1 (en) * 1979-11-16 1985-10-31 Sterosynt Ltd 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates
IL66432A0 (en) * 1981-08-04 1982-12-31 Plurichemie Anstalt Process for the preparation of steroidal esters
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
KR880001237B1 (ko) * 1984-07-25 1988-07-12 호비온 인터 리미티드 베클로메타손 17,21-디프로피오네이트의 용매화합물의 제조방법
JPS61180354U (es) * 1985-04-25 1986-11-11

Also Published As

Publication number Publication date
JPH037679B2 (es) 1991-02-04
DK334585D0 (da) 1985-07-23
AU571986B2 (en) 1988-04-28
NZ212876A (en) 1988-05-30
ES8606878A1 (es) 1986-06-01
JPS6153297A (ja) 1986-03-17
EP0170500B1 (en) 1990-10-10
KR860001123A (ko) 1986-02-22
KR880001238B1 (ko) 1988-07-12
JPS6354392A (ja) 1988-03-08
AU4530685A (en) 1986-01-30
DE3580072D1 (de) 1990-11-15
IE58941B1 (en) 1993-12-01
IE851851L (en) 1986-01-25
DK334585A (da) 1986-01-26
EP0170500A2 (en) 1986-02-05
IL75871A (en) 1989-05-15
ATE57384T1 (de) 1990-10-15
DK167617B1 (da) 1993-11-29
US5026693A (en) 1991-06-25
CA1307257C (en) 1992-09-08
ZA855621B (en) 1986-03-26
EP0170500A3 (en) 1986-06-11
PT78973A (en) 1984-08-01
HK107990A (en) 1990-12-28
IL75871A0 (en) 1985-11-29
JPH0215559B2 (es) 1990-04-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060222