ES546633A0 - Un procedimiento para la obtencion de nuevas cefalosporinas utiles en la lucha contra las enfermedades infecciosas - Google Patents

Un procedimiento para la obtencion de nuevas cefalosporinas utiles en la lucha contra las enfermedades infecciosas

Info

Publication number: ES546633A0
Authority: ES; Spain
Prior art keywords: ring; procedure; substituted; infectious diseases; fight against
Prior art date: 1983-11-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES546633A

Other languages

English (en)

Other versions

ES8604977A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer AG

Original Assignee

Bayer AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-11-30

Filing date

1985-09-02

Publication date

1986-03-01

1985-09-02 Application filed by Bayer AG filed Critical Bayer AG

1986-03-01 Publication of ES8604977A1 publication Critical patent/ES8604977A1/es

1986-03-01 Publication of ES546633A0 publication Critical patent/ES546633A0/es

Status Expired legal-status Critical Current

Links

229930186147 Cephalosporin Natural products 0.000 title abstract 2
229940124587 cephalosporin Drugs 0.000 title abstract 2
208000035473 Communicable disease Diseases 0.000 title 1
HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001780 cephalosporins Chemical class 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
230000004962 physiological condition Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ES546633A 1983-11-30 1985-09-02 Un procedimiento para la obtencion de nuevas cefalosporinas utiles en la lucha contra las enfermedades infecciosas Expired ES8604977A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19833343208 DE3343208A1 (de)	1983-11-30	1983-11-30	Neue cephalosporine und verfahren zu ihrer herstellung

Publications (2)

Publication Number	Publication Date
ES8604977A1 ES8604977A1 (es)	1986-03-01
ES546633A0 true ES546633A0 (es)	1986-03-01

Family

ID=6215587

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES537857A Granted ES537857A0 (es)	1983-11-30	1984-11-22	Nuevas cefalosporinas y procedimientos para su obtencion
ES546633A Expired ES8604977A1 (es)	1983-11-30	1985-09-02	Un procedimiento para la obtencion de nuevas cefalosporinas utiles en la lucha contra las enfermedades infecciosas
ES546632A Expired ES8604976A1 (es)	1983-11-30	1985-09-02	Un procedimiento para la obtencion de nuevas cefalosporinas utiles en la lucha contra las enfermedades infecciosas

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ES537857A Granted ES537857A0 (es)	1983-11-30	1984-11-22	Nuevas cefalosporinas y procedimientos para su obtencion

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES546632A Expired ES8604976A1 (es)	1983-11-30	1985-09-02	Un procedimiento para la obtencion de nuevas cefalosporinas utiles en la lucha contra las enfermedades infecciosas

Country Status (16)

Country	Link
US (2)	US4757065A (es)
EP (1)	EP0144032B1 (es)
JP (1)	JPS60136587A (es)
KR (1)	KR850003540A (es)
AT (1)	ATE36160T1 (es)
AU (1)	AU572916B2 (es)
CA (1)	CA1275285C (es)
DE (2)	DE3343208A1 (es)
DK (1)	DK568484A (es)
ES (3)	ES537857A0 (es)
GR (1)	GR81082B (es)
HU (1)	HU193470B (es)
IL (1)	IL73644A (es)
PH (1)	PH22176A (es)
PT (1)	PT79552B (es)
ZA (1)	ZA849319B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3419012A1 (de) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
AU580855B2 (en) *	1985-03-29	1989-02-02	Shionogi & Co., Ltd.	Alkeneamidocephalosporin esters
US5171854A (en) *	1987-05-26	1992-12-15	Bayer Aktiengesellschaft	Substituted vinylcephalosporins
DE3807232A1 (de) *	1988-03-05	1989-09-14	Bayer Ag	Substituierte acrylsaeureester
US5285455A (en) *	1992-02-03	1994-02-08	Lsi Logic Corporation	Serial data encoder
US5471485A (en) *	1992-11-24	1995-11-28	Lsi Logic Corporation	Reed-solomon decoder using discrete time delay in power sum computation
KR101809072B1 (ko)	2013-08-02	2017-12-14	화이자 인코포레이티드	항-cxcr4 항체 및 항체-약물 접합체
CN110294770A (zh) *	2019-08-14	2019-10-01	齐鲁晟华制药有限公司	一种头孢烯类鎓盐化合物、制备方法及以该化合物合成头孢喹肟的方法
CN113801142A (zh) *	2021-10-28	2021-12-17	重庆医药高等专科学校	一种硫酸头孢喹肟中间体7-氨基头孢喹肟的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1497039A (en) *	1973-12-05	1978-01-05	Glaxo Lab Ltd	Penicillins and cephalosporins
GB2076801A (en) *	1980-04-14	1981-12-09	Erba Farmitalia	alpha , beta -Disubstituted Acrylamido Cephalosporins
DE3037997A1 (de) *	1980-10-08	1982-05-13	Bayer Ag	(beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
JPS5818387A (ja) *	1981-07-27	1983-02-02	Sagami Chem Res Center	β−ラクタム誘導体
DE3145727A1 (de) *	1981-11-19	1983-05-26	Bayer Ag, 5090 Leverkusen	Zwischenprodukte, verfahren zu deren herstellung und verfahren zur herstellung von cephalosporinen
DE3239365A1 (de) *	1982-10-23	1984-04-26	Bayer Ag, 5090 Leverkusen	Neue cephalosporine und verfahren zu ihrer herstellung
DE3419012A1 (de) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien

1983
- 1983-11-30 DE DE19833343208 patent/DE3343208A1/de not_active Withdrawn
1984
- 1984-11-16 AU AU35676/84A patent/AU572916B2/en not_active Ceased
- 1984-11-17 EP EP84113927A patent/EP0144032B1/de not_active Expired
- 1984-11-17 AT AT84113927T patent/ATE36160T1/de not_active IP Right Cessation
- 1984-11-17 DE DE8484113927T patent/DE3473146D1/de not_active Expired
- 1984-11-20 US US06/673,246 patent/US4757065A/en not_active Expired - Fee Related
- 1984-11-22 ES ES537857A patent/ES537857A0/es active Granted
- 1984-11-26 PT PT79552A patent/PT79552B/pt unknown
- 1984-11-27 IL IL73644A patent/IL73644A/xx unknown
- 1984-11-27 PH PH31497A patent/PH22176A/en unknown
- 1984-11-28 GR GR81082A patent/GR81082B/el unknown
- 1984-11-28 CA CA000468785A patent/CA1275285C/en not_active Expired - Lifetime
- 1984-11-29 ZA ZA849319A patent/ZA849319B/xx unknown
- 1984-11-29 JP JP59250658A patent/JPS60136587A/ja active Pending
- 1984-11-29 HU HU844415A patent/HU193470B/hu not_active IP Right Cessation
- 1984-11-29 KR KR1019840007516A patent/KR850003540A/ko not_active Ceased
- 1984-11-29 DK DK568484A patent/DK568484A/da not_active Application Discontinuation
1985
- 1985-09-02 ES ES546633A patent/ES8604977A1/es not_active Expired
- 1985-09-02 ES ES546632A patent/ES8604976A1/es not_active Expired
1986
- 1986-10-30 US US06/926,027 patent/US4767754A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES8604976A1 (es)	1986-03-01
DK568484A (da)	1985-05-31
DK568484D0 (da)	1984-11-29
IL73644A (en)	1989-02-28
ES8604977A1 (es)	1986-03-01
PT79552A (en)	1984-12-01
ZA849319B (en)	1985-07-31
IL73644A0 (en)	1985-02-28
EP0144032A3 (en)	1986-03-19
GR81082B (en)	1985-03-27
JPS60136587A (ja)	1985-07-20
HUT37623A (en)	1986-01-23
AU572916B2 (en)	1988-05-19
CA1275285C (en)	1990-10-16
HU193470B (en)	1987-10-28
US4767754A (en)	1988-08-30
US4757065A (en)	1988-07-12
PT79552B (en)	1986-09-15
ES8603896A1 (es)	1986-01-01
AU3567684A (en)	1985-06-06
KR850003540A (ko)	1985-06-20
ES546632A0 (es)	1986-03-01
EP0144032A2 (de)	1985-06-12
DE3343208A1 (de)	1985-06-05
ATE36160T1 (de)	1988-08-15
EP0144032B1 (de)	1988-08-03
PH22176A (en)	1988-06-28
ES537857A0 (es)	1986-01-01
DE3473146D1 (en)	1988-09-08

Publication	Publication Date	Title
NO161495C (no)	1989-08-23	Fremgangsmaate for fremstilling av (d-alfa-amino-(p-hydroksyfenyl)acetamido))-gruppeholdige cefalosporansyrederivater.
SE7614678L (sv)	1977-07-24	Sett att framstella nya oximderivat av 7-aminotiazolyl-acetamido-cefalosporansyraderivat
ES546632A0 (es)	1986-03-01	Un procedimiento para la obtencion de nuevas cefalosporinas utiles en la lucha contra las enfermedades infecciosas
ATA661577A (de)	1981-10-15	Verfahren zur herstellung von neuen, optisch akti-ven 3-azabicyclo(3.1.0)hexanderivaten und ihren nichttoxischen, pharmazeutisch vertraeglichen salzen
GB2108495B (en)	1985-07-24	Triazoloquinazolone derivatives
DE3373476D1 (en)	1987-10-15	Cephalosporin derivatives and process for their preparation
ES469182A1 (es)	1979-09-16	Un procedimiento para la preparacion de nuevos derivados de acido clavulanico
MA19841A1 (fr)	1984-04-01	Procede de preparation de nouveaux derives de cephalosporines utilisables comme antibiotiques .
BG35899A3 (bg)	1984-07-16	Метод за получаване на пеницилинови и цефалоспоринови иминохалогениди
DE3060314D1 (en)	1982-06-09	Heterocyclic spiro-amidines, their stereoisomers and optical isomers, methods for their preparation and medicaments containing them
PH20367A (en)	1986-12-04	Cephalosporin derivatives and pharmaceutical preparations containing them
ES515047A0 (es)	1983-05-01	Procedimiento para la obtencion de derivados de cefalosporina.
FI833971A0 (fi)	1983-10-31	Nya semikarbazider, deras framstaellning och anvaendning