ES551367A0 - Un procedimiento para preparar agentes quelantes (ligandos) del tipo de poliaminoditioles (como divisional de la solicitud de patente de invencion no. 542.678, presentada el 29 de abril de 1985) - Google Patents
Un procedimiento para preparar agentes quelantes (ligandos) del tipo de poliaminoditioles (como divisional de la solicitud de patente de invencion no. 542.678, presentada el 29 de abril de 1985)Info
- Publication number
- ES551367A0 ES551367A0 ES551367A ES551367A ES551367A0 ES 551367 A0 ES551367 A0 ES 551367A0 ES 551367 A ES551367 A ES 551367A ES 551367 A ES551367 A ES 551367A ES 551367 A0 ES551367 A0 ES 551367A0
- Authority
- ES
- Spain
- Prior art keywords
- polyaminoditiols
- divisional
- agents
- leading
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60536884A | 1984-04-30 | 1984-04-30 | |
| US06/723,011 US4638051A (en) | 1984-04-30 | 1985-04-17 | Brain imaging radiopharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8704892A1 ES8704892A1 (es) | 1987-04-16 |
| ES551367A0 true ES551367A0 (es) | 1987-04-16 |
Family
ID=27084932
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES542678A Expired ES8608531A1 (es) | 1984-04-30 | 1985-04-29 | Un procedimiento para preparar compuestos de tecnecio-99 deltipo de coordinacion |
| ES551367A Expired ES8704892A1 (es) | 1984-04-30 | 1986-01-29 | Un procedimiento para preparar agentes quelantes (ligandos) del tipo de poliaminoditioles (como divisional de la solicitud de patente de invencion no. 542.678, presentada el 29 de abril de 1985) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES542678A Expired ES8608531A1 (es) | 1984-04-30 | 1985-04-29 | Un procedimiento para preparar compuestos de tecnecio-99 deltipo de coordinacion |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4638051A (es) |
| EP (1) | EP0163119B1 (es) |
| AU (1) | AU4177785A (es) |
| CA (1) | CA1225996A (es) |
| DE (1) | DE3565981D1 (es) |
| DK (2) | DK193885A (es) |
| ES (2) | ES8608531A1 (es) |
| FI (1) | FI851684L (es) |
| GR (1) | GR851051B (es) |
| NO (1) | NO851696L (es) |
| PT (1) | PT80378B (es) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4897255A (en) * | 1985-01-14 | 1990-01-30 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| US4746505A (en) * | 1985-04-26 | 1988-05-24 | President And Fellows Of Harvard College | Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands |
| EP0200211A1 (en) * | 1985-05-01 | 1986-11-05 | The Research Foundation Of State University Of New York | Diagnostic radiopharmaceutical compounds |
| US5279811A (en) * | 1987-02-18 | 1994-01-18 | The Du Pont Merck Pharmaceutical Company | Ester-substituted diaminedithiols and radiolabeled complexes thereof |
| US5177192A (en) * | 1987-04-02 | 1993-01-05 | Centocor, Incorporated | Method for labeling antibodies with a metal ion |
| US5053493A (en) * | 1987-04-02 | 1991-10-01 | Centocor Cardiovascular Imaging Partners, L.P. | Method for labeling antibodies with a metal ion |
| US5071636A (en) * | 1987-12-29 | 1991-12-10 | Nihon Medi-Physics Co., Ltd. | Chelating compounds and their use |
| US5202451A (en) * | 1988-02-17 | 1993-04-13 | Neorx Corporation | Anchimeric radiometal chelating compounds |
| EP0381713B1 (en) * | 1988-04-29 | 1994-01-19 | Mallinckrodt, Inc. | Diaminedithiol chelating agents for radiopharmaceuticals |
| US4988496A (en) * | 1988-05-31 | 1991-01-29 | Neorx Corporation | Metal radionuclide chelating compounds for improved chelation kinetics |
| US5075099A (en) * | 1988-05-31 | 1991-12-24 | Neorx Corporation | Metal radionuclide chelating compounds for improved chelation kinetics |
| US5202109A (en) * | 1988-06-10 | 1993-04-13 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
| US5089249A (en) * | 1988-06-10 | 1992-02-18 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
| US4992255A (en) * | 1988-12-19 | 1991-02-12 | Pardridge William M | Capillary depletion method for quantifying transcytosis through the blood-brain barrier |
| FR2646157B1 (fr) * | 1989-04-19 | 1991-08-30 | Ire Medgenix Sa | Ligands et complexes utiles notamment en imagerie medicale |
| FR2655339B2 (fr) * | 1989-04-19 | 1992-04-10 | Medgenix Group Sa | Composes et complexes utiles notamment en imagerie medicale. |
| US5080884A (en) * | 1989-12-12 | 1992-01-14 | Medi-Physics, Inc. | Hydrocarbylphenyl diaminodithiol radionuclide complexes and their use in imaging |
| EP0432988B1 (en) * | 1989-12-12 | 1994-02-16 | AMERSHAM INTERNATIONAL plc | Hydrocarbylphenyl diaminodithiol derivatives |
| US5026913A (en) * | 1989-12-12 | 1991-06-25 | Medi-Physics, Inc. | Hydrocarbylphenyl diaminodithiol derivatives |
| WO1991016076A1 (en) * | 1990-04-17 | 1991-10-31 | Mallinckrodt Medical, Inc. | Method and kit for preparing technetium-99m complexes |
| DE4025788C2 (de) * | 1990-08-10 | 1994-04-14 | Diagnostikforschung Inst | Technetium- und Rhenium-Komplexe, Verfahren zu ihrer Herstellung sowie deren Verwendung in Diagnostik und Therapie |
| JP2860157B2 (ja) * | 1990-10-31 | 1999-02-24 | 日本メジフィジックス株式会社 | 腎機能測定用の既放射能標識テクネチウムキレート注射剤の製造方法 |
| US5997844A (en) * | 1991-02-08 | 1999-12-07 | Diatide, Inc. | Technetium-99m labeled peptides for imaging |
| US5736122A (en) * | 1991-02-08 | 1998-04-07 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
| JP2774378B2 (ja) * | 1991-02-08 | 1998-07-09 | ダイアテク,インコーポレイテッド | 映像用テクネチウム−99m標識化ポリペプチド |
| US5965107A (en) * | 1992-03-13 | 1999-10-12 | Diatide, Inc. | Technetium-99m labeled peptides for imaging |
| US7238340B1 (en) | 1991-11-27 | 2007-07-03 | Cis Bio International | Monoamine, diamide, thiol-containing metal chelating agents |
| US5645815A (en) | 1991-02-08 | 1997-07-08 | Diatide, Inc. | Radiolabled compounds for thrombus imaging |
| NZ244613A (en) * | 1991-10-29 | 1996-05-28 | Bracco International B V Subst | A ligand containing a hypoxia-localising moiety, preparation thereof; a kit (optionally multivial) for preparing a metal complex containing the ligand |
| US5808091A (en) | 1991-10-29 | 1998-09-15 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia localizing moiety |
| EP0630264B1 (en) * | 1992-02-06 | 2002-11-06 | BioSynthema Inc. | Ligands for improving metal chelate formation kinetics |
| US5310536A (en) * | 1992-02-06 | 1994-05-10 | Mallinckrodt Medical, Inc. | Ligands for improving metal chelate formation kinetics |
| US5968476A (en) * | 1992-05-21 | 1999-10-19 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
| ATE329624T1 (de) * | 1992-05-21 | 2006-07-15 | Diatide Inc | Technetium-99m markierte peptide zur bilderzeugung von thrombus |
| US5879657A (en) * | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
| US5608110A (en) * | 1993-06-15 | 1997-03-04 | Bracco International B.V. | Heteroatom-bearing ligands and metal complexes thereof |
| US5690904A (en) * | 1993-07-12 | 1997-11-25 | Amersham International Plc | Diagnostic radiopharmaceutical compounds (That) |
| JP5186075B2 (ja) * | 2000-04-28 | 2013-04-17 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | テクネチウム−99m及びレニウムで標識した小型作用剤及び腫瘍の画像化方法 |
| JP4796301B2 (ja) * | 2002-11-08 | 2011-10-19 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | テクネチウム−99m及びレニウムで標識した小型作用剤及び組織、臓器及び腫瘍の画像化方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU82738A1 (fr) * | 1980-08-29 | 1982-05-10 | Continental Pharma | Derives d'aminothiols,leur preparation et utilisation ainsi que compositions contenant ces derives |
| JPS57212193A (en) * | 1981-06-25 | 1982-12-27 | Daiichi Rajio Isotope Kenkyusho:Kk | Compound labeled with technetium |
| US4444690A (en) * | 1982-02-25 | 1984-04-24 | University Patents, Inc. | Technetium chelates |
| US4434151A (en) * | 1982-11-08 | 1984-02-28 | Medi-Physics, Inc. | Bifunctional chelating agents |
| US4673562A (en) * | 1983-08-19 | 1987-06-16 | The Children's Medical Center Corporation | Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents |
-
1985
- 1985-04-17 US US06/723,011 patent/US4638051A/en not_active Expired - Fee Related
- 1985-04-24 EP EP85104959A patent/EP0163119B1/en not_active Expired
- 1985-04-24 DE DE8585104959T patent/DE3565981D1/de not_active Expired
- 1985-04-25 CA CA000480061A patent/CA1225996A/en not_active Expired
- 1985-04-29 ES ES542678A patent/ES8608531A1/es not_active Expired
- 1985-04-29 AU AU41777/85A patent/AU4177785A/en not_active Abandoned
- 1985-04-29 FI FI851684A patent/FI851684L/fi not_active Application Discontinuation
- 1985-04-29 NO NO851696A patent/NO851696L/no unknown
- 1985-04-30 PT PT80378A patent/PT80378B/pt not_active IP Right Cessation
- 1985-04-30 GR GR851051A patent/GR851051B/el unknown
- 1985-04-30 DK DK193885A patent/DK193885A/da unknown
-
1986
- 1986-01-29 ES ES551367A patent/ES8704892A1/es not_active Expired
-
1991
- 1991-11-05 DK DK182391A patent/DK182391A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES8608531A1 (es) | 1986-06-16 |
| DK193885D0 (da) | 1985-04-30 |
| PT80378B (pt) | 1987-09-30 |
| DK182391D0 (da) | 1991-11-05 |
| EP0163119B1 (en) | 1988-11-02 |
| FI851684A0 (fi) | 1985-04-29 |
| DK182391A (da) | 1991-11-05 |
| ES8704892A1 (es) | 1987-04-16 |
| US4638051A (en) | 1987-01-20 |
| FI851684A7 (fi) | 1985-10-31 |
| AU4177785A (en) | 1985-11-07 |
| FI851684L (fi) | 1985-10-31 |
| DE3565981D1 (en) | 1988-12-08 |
| GR851051B (es) | 1985-11-25 |
| DK193885A (da) | 1985-10-31 |
| PT80378A (en) | 1985-05-01 |
| EP0163119A2 (en) | 1985-12-04 |
| ES542678A0 (es) | 1986-06-16 |
| EP0163119A3 (en) | 1986-10-08 |
| CA1225996A (en) | 1987-08-25 |
| NO851696L (no) | 1985-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |