ES552563A0 - Un procedimiento para la preparacion de nuevos derivados de siraxina. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de siraxina.Info
- Publication number
- ES552563A0 ES552563A0 ES552563A ES552563A ES552563A0 ES 552563 A0 ES552563 A0 ES 552563A0 ES 552563 A ES552563 A ES 552563A ES 552563 A ES552563 A ES 552563A ES 552563 A0 ES552563 A0 ES 552563A0
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- siraxin
- procedure
- preparation
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- OWPCHSCAPHNHAV-LMONGJCWSA-N rhizoxin Chemical class C/C([C@H](OC)[C@@H](C)[C@@H]1C[C@H](O)[C@]2(C)O[C@@H]2/C=C/[C@@H](C)[C@]2([H])OC(=O)C[C@@](C2)(C[C@@H]2O[C@H]2C(=O)O1)[H])=C\C=C\C(\C)=C\C1=COC(C)=N1 OWPCHSCAPHNHAV-LMONGJCWSA-N 0.000 abstract 2
- OWPCHSCAPHNHAV-UHFFFAOYSA-N Rhizoxin Natural products C1C(O)C2(C)OC2C=CC(C)C(OC(=O)C2)CC2CC2OC2C(=O)OC1C(C)C(OC)C(C)=CC=CC(C)=CC1=COC(C)=N1 OWPCHSCAPHNHAV-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3939985 | 1985-02-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8705449A1 ES8705449A1 (es) | 1987-05-01 |
| ES552563A0 true ES552563A0 (es) | 1987-05-01 |
Family
ID=12551912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES552563A Expired ES8705449A1 (es) | 1985-02-28 | 1986-02-28 | Un procedimiento para la preparacion de nuevos derivados de siraxina. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4791128A (es) |
| EP (1) | EP0218310B1 (es) |
| JP (1) | JPS6287A (es) |
| CN (1) | CN1009554B (es) |
| AT (1) | ATE61590T1 (es) |
| CA (1) | CA1271763A (es) |
| DE (1) | DE3678086D1 (es) |
| ES (1) | ES8705449A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07116198B2 (ja) * | 1987-04-02 | 1995-12-13 | 三共株式会社 | リゾキシン誘導体 |
| JPS63295447A (ja) * | 1987-05-27 | 1988-12-01 | Matsushita Electric Ind Co Ltd | 光学ガラス素子の製造方法 |
| CA1334757C (en) * | 1988-07-06 | 1995-03-14 | Masakatsu Kaneko | Rhizoxin derivatives and their use as anti-tumor agents |
| US5352689A (en) * | 1988-07-06 | 1994-10-04 | Sankyo Company, Limited | Rhizoxin derivatives and their use as anti-tumor agents |
| AU3905993A (en) * | 1992-04-28 | 1993-11-29 | Sankyo Company Limited | Fat emulsion containing fatty acid ester of rhizoxin |
| DE102012000956A1 (de) * | 2011-06-21 | 2012-12-27 | Leibniz-Institut Für Naturstoff-Forschung Und Infektionsbiologie | Neue Rhizoxinderivate |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6084220A (ja) * | 1983-10-17 | 1985-05-13 | Norin Suisansyo Nogyo Kankyo Gijutsu Kenkyusho | 植物病原菌リゾ−プス・キネンシスの代謝産物リゾキシンを有効成分とする抗腫瘍剤 |
-
1986
- 1986-02-28 EP EP86301465A patent/EP0218310B1/en not_active Expired - Lifetime
- 1986-02-28 JP JP61042007A patent/JPS6287A/ja active Granted
- 1986-02-28 AT AT86301465T patent/ATE61590T1/de active
- 1986-02-28 CA CA000503062A patent/CA1271763A/en not_active Expired - Fee Related
- 1986-02-28 ES ES552563A patent/ES8705449A1/es not_active Expired
- 1986-02-28 CN CN86102020A patent/CN1009554B/zh not_active Expired
- 1986-02-28 DE DE8686301465T patent/DE3678086D1/de not_active Expired - Fee Related
-
1988
- 1988-01-11 US US07/143,314 patent/US4791128A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES8705449A1 (es) | 1987-05-01 |
| US4791128A (en) | 1988-12-13 |
| ATE61590T1 (de) | 1991-03-15 |
| CN86102020A (zh) | 1986-10-01 |
| JPH0474356B2 (es) | 1992-11-26 |
| CN1009554B (zh) | 1990-09-12 |
| EP0218310A3 (en) | 1987-12-23 |
| DE3678086D1 (de) | 1991-04-18 |
| EP0218310A2 (en) | 1987-04-15 |
| EP0218310B1 (en) | 1991-03-13 |
| JPS6287A (ja) | 1987-01-06 |
| CA1271763A (en) | 1990-07-17 |
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