ES553472A0 - Un procedimiento para preparar un anticuerpo monoclonal - Google Patents

Un procedimiento para preparar un anticuerpo monoclonal

Info

Publication number
ES553472A0
ES553472A0 ES553472A ES553472A ES553472A0 ES 553472 A0 ES553472 A0 ES 553472A0 ES 553472 A ES553472 A ES 553472A ES 553472 A ES553472 A ES 553472A ES 553472 A0 ES553472 A0 ES 553472A0
Authority
ES
Spain
Prior art keywords
monoclonal antibody
hba1c
preparing
procedure
hemoglobin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES553472A
Other languages
English (en)
Other versions
ES8800351A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of ES8800351A1 publication Critical patent/ES8800351A1/es
Publication of ES553472A0 publication Critical patent/ES553472A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES553472A 1985-03-29 1986-03-26 Un procedimiento para preparar un anticuerpo monoclonal Expired ES8800351A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK145385A DK145385D0 (da) 1985-03-29 1985-03-29 Monoklonalt antistof til immunkemisk analyse

Publications (2)

Publication Number Publication Date
ES8800351A1 ES8800351A1 (es) 1987-10-16
ES553472A0 true ES553472A0 (es) 1987-10-16

Family

ID=8104987

Family Applications (1)

Application Number Title Priority Date Filing Date
ES553472A Expired ES8800351A1 (es) 1985-03-29 1986-03-26 Un procedimiento para preparar un anticuerpo monoclonal

Country Status (10)

Country Link
EP (1) EP0201187B1 (es)
JP (1) JPH0720437B2 (es)
AT (1) ATE72052T1 (es)
AU (1) AU584688B2 (es)
DE (1) DE3683532D1 (es)
DK (2) DK145385D0 (es)
ES (1) ES8800351A1 (es)
FI (1) FI89379B (es)
GR (1) GR860833B (es)
PT (1) PT82296B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339952C (en) * 1984-10-29 1998-07-14 William J. Knowles Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto
US4727036A (en) * 1985-08-08 1988-02-23 Molecular Diagnostics, Inc. Antibodies for use in determining hemoglobin A1c
US4876188A (en) * 1986-11-18 1989-10-24 Scripps Clinic And Research Foundation Novel immunochemical method for assaying stable glycosylated hemoglobin
JPS63273472A (ja) * 1987-04-30 1988-11-10 Asahi Breweries Ltd 新規抗体とそれを用いたヒトヘモグロビンの検出
US4970171A (en) * 1987-11-09 1990-11-13 Miles Inc. Denaturant reagents for convenient determination of hemoglobin derivatives in blood
DE3806198A1 (de) * 1988-02-04 1989-08-17 Boehringer Mannheim Gmbh Immunogen und seine verwendung zur gewinnung von antikoerpern gegen hba(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)c(pfeil abwaerts)
US5484735A (en) * 1989-08-23 1996-01-16 Northwestern University Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids
JP3124028B2 (ja) * 1989-08-23 2001-01-15 ノースウェスターン ユニヴァーシティ 還元的にグリコシル化されたｎ―末端アミノ酸に向けられた抗原を使用するグリコシル化されたタンパクの免疫学的測定法
US5183739A (en) * 1990-02-27 1993-02-02 Exocell, Inc. Monoclonal antibodies specific for non-a1c glycated hemoglobin and immunoassay methods
DE4206932A1 (de) * 1992-03-05 1993-09-09 Boehringer Mannheim Gmbh Immunologische methode zur bestimmung eines haemoglobinderivates
JP2596322B2 (ja) * 1992-06-10 1997-04-02 富士レビオ株式会社 総ヘモグロビンに対する糖化ヘモグロビンの割合の測定方法
US5470759A (en) * 1992-06-10 1995-11-28 Fujirebio, Inc. Anti-glycated hemoglobin monoclonal antibody and method for measuring glycated hemoglobin
JP2596321B2 (ja) * 1992-06-16 1997-04-02 富士レビオ株式会社 糖化ヘモグロビンの測定方法
WO1994000592A1 (en) * 1992-06-26 1994-01-06 Exocell, Inc. Monoclonal antibodies against glycated low density lipoprotein
AU661207B2 (en) * 1992-11-17 1995-07-13 Boehringer Mannheim Gmbh Simultaneous determination of HbA1c and haemoglobin variants with a glycation analogus to HbA1c
JP3269765B2 (ja) 1995-12-14 2002-04-02 富士写真フイルム株式会社 ヘモグロビン誘導体の免疫学的測定方法及びその方法に用いる処理試薬
JP3801133B2 (ja) * 2000-07-14 2006-07-26 松下電器産業株式会社 ペプチドフルクトース及びそのタンパク質結合体
WO2005023291A2 (en) * 2003-09-11 2005-03-17 Novo Nordisk A/S Use of glp1-agonists in the treatment of patients with type i diabetes
EP2848942B1 (en) 2004-07-14 2017-03-08 The Regents of The University of California Biomarkers for early detection of ovarian cancer
US9487575B2 (en) 2004-07-14 2016-11-08 The Regents Of The University Of California Compositions and methods for treatment of gynecologic cancers
US7670792B2 (en) 2004-07-14 2010-03-02 The Regents Of The University Of California Biomarkers for early detection of ovarian cancer
US9488655B2 (en) 2004-07-14 2016-11-08 The Regents Of The University Of California Biomarkers for detection of early- and late-stage endometrial cancer
JP6078067B2 (ja) 2011-08-29 2017-02-08 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 炎症誘発性状態の治療および予防のためのｈｄｌ関連分子の使用
JP6822957B2 (ja) 2015-07-30 2021-01-27 京セラ株式会社 測定方法、および測定装置
WO2020148395A1 (en) * 2019-01-17 2020-07-23 Roche Diagnostics Gmbh Automatic sample workflow for lc-ms based hba1c measurement on intact protein level
MX2020005703A (es) * 2020-07-13 2022-01-14 Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C Secuencias de dominios vnar de potamotrygon schroederi y composiciones para el reconocimiento de hemoglobina glicada humana.
CN118772272B (zh) * 2024-09-12 2024-11-08 南京立顶医疗科技有限公司 一种靶向HbA1c的重组IgM型抗体及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247533A (en) * 1978-05-01 1981-01-27 The Rockefeller University Hemoglobin A1c radioimmunoassay
GB1580318A (en) 1978-05-06 1980-12-03 Univ Rockefeller Antibodies active against human hemoglobin a1c
US4478744A (en) 1982-01-25 1984-10-23 Sherwood Medical Company Method of obtaining antibodies
US4629692A (en) * 1982-12-06 1986-12-16 Miles Laboratories, Inc. Immunoassay for nonenzymatically glucosylated proteins and protein fragments an index of glycemia
AU529210B3 (en) * 1983-02-02 1983-04-14 Australian Monoclonal Development Pty. Ltd. Monoclonal antibody in occult blood diagnosis
JPS59202064A (ja) * 1983-04-30 1984-11-15 Fujirebio Inc 抗原決定基具有物質を測定する方法
CA1339952C (en) * 1984-10-29 1998-07-14 William J. Knowles Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto

Also Published As

Publication number Publication date
JPH0720437B2 (ja) 1995-03-08
DK159826C (da) 1991-04-29
PT82296A (en) 1986-04-01
EP0201187B1 (en) 1992-01-22
DK129986A (da) 1986-09-30
DK159826B (da) 1990-12-10
AU5532186A (en) 1986-10-02
PT82296B (pt) 1988-07-29
ES8800351A1 (es) 1987-10-16
DK129986D0 (da) 1986-03-21
DK145385D0 (da) 1985-04-01
GR860833B (en) 1986-07-29
ATE72052T1 (de) 1992-02-15
EP0201187A1 (en) 1986-11-12
FI861358L (fi) 1986-09-30
FI89379B (fi) 1993-06-15
FI861358A0 (fi) 1986-03-27
DE3683532D1 (de) 1992-03-05
JPS61280571A (ja) 1986-12-11
AU584688B2 (en) 1989-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601