ES8100282A1 - Procedimiento para la obtencion de nuevos derivados de la piperacina metanimina - Google Patents

Procedimiento para la obtencion de nuevos derivados de la piperacina metanimina

Info

Publication number
ES8100282A1
ES8100282A1 ES480637A ES480637A ES8100282A1 ES 8100282 A1 ES8100282 A1 ES 8100282A1 ES 480637 A ES480637 A ES 480637A ES 480637 A ES480637 A ES 480637A ES 8100282 A1 ES8100282 A1 ES 8100282A1
Authority
ES
Spain
Prior art keywords
radical
branched
unsaturated
straight
saturated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480637A
Other languages
English (en)
Other versions
ES480637A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laroche Navarron SA
Original Assignee
Laroche Navarron SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laroche Navarron SA filed Critical Laroche Navarron SA
Publication of ES8100282A1 publication Critical patent/ES8100282A1/es
Publication of ES480637A0 publication Critical patent/ES480637A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE LA PIPERACINA METANIMINA. CONSISTE EN HACER REACCIONAR SOBRE UNA PIPERACINA DE FORMULA GENERAL: UN IMINOATO DE ALQUILO, UNA BENZAMIDINA Y UN YODHIDRATO DE TIOBENCIMIDATO DE S-METILO, OBTENIENDOSE UN COMPUESTO DE FORMULA: *FORMULA*.
ES480637A 1978-04-27 1979-04-26 Procedimiento para la obtencion de nuevos derivados de la piperacina metanimina Granted ES480637A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1674478 1978-04-27

Publications (2)

Publication Number Publication Date
ES8100282A1 true ES8100282A1 (es) 1980-11-01
ES480637A0 ES480637A0 (es) 1980-11-01

Family

ID=10082882

Family Applications (2)

Application Number Title Priority Date Filing Date
ES480637A Granted ES480637A0 (es) 1978-04-27 1979-04-26 Procedimiento para la obtencion de nuevos derivados de la piperacina metanimina
ES488835A Expired ES8103740A1 (es) 1978-04-27 1980-01-31 Procedimiento para la obtencion de nuevos derivados de la piperacina metanimina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES488835A Expired ES8103740A1 (es) 1978-04-27 1980-01-31 Procedimiento para la obtencion de nuevos derivados de la piperacina metanimina

Country Status (16)

Country Link
US (1) US4259334A (es)
EP (1) EP0005385B1 (es)
JP (1) JPS55370A (es)
AT (1) AT375358B (es)
AU (1) AU521238B2 (es)
CA (1) CA1127156A (es)
CS (1) CS226185B2 (es)
DE (1) DE2963600D1 (es)
ES (2) ES480637A0 (es)
FI (1) FI69841C (es)
HU (1) HU178272B (es)
IE (1) IE47950B1 (es)
NZ (1) NZ190293A (es)
OA (1) OA06247A (es)
PH (1) PH15270A (es)
ZA (1) ZA791944B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400381A (en) * 1981-07-31 1983-08-23 Laroche-Navarron, S.A. Piperazine derivatives of theophylline
US4374837A (en) * 1981-07-31 1983-02-22 Laroche Navarron, S.A. Piperazine derivatives of theobromine
US4515947A (en) * 1982-08-11 1985-05-07 Eastman Kodak Company Cyanoalkylpiperazines and methods for their preparation and use
US4713382A (en) * 1985-05-30 1987-12-15 Syntex (U.S.A.) Inc. N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents
AU7446900A (en) 1999-09-28 2001-04-30 Nihon Nohyaku Co., Ltd. Thioalkylamine derivatives and process for the preparation thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1810836A1 (de) * 1967-12-28 1970-01-08 Chinoin Gyogyszer Es Vegyeszet Neue Benzamidinderivate und Verfahren zur Herstellung derselben
US4115569A (en) * 1971-11-19 1978-09-19 Hoechst Aktiengesellschaft Cyclic diamine derivatives
CA1012540A (en) * 1972-06-17 1977-06-21 Sumitomo Chemical Company 2-propanol derivatives and preparation thereof
US3793322A (en) * 1972-12-15 1974-02-19 Usv Pharma Corp 1,4-disubstituted piperazines

Also Published As

Publication number Publication date
ES480637A0 (es) 1980-11-01
ES488835A0 (es) 1981-03-16
AU521238B2 (en) 1982-03-25
HU178272B (en) 1982-04-28
EP0005385A1 (fr) 1979-11-14
IE47950B1 (en) 1984-07-25
AU4633179A (en) 1979-11-01
EP0005385B1 (fr) 1982-09-01
AT375358B (de) 1984-07-25
PH15270A (en) 1982-11-02
OA06247A (fr) 1981-06-30
US4259334A (en) 1981-03-31
FI69841B (fi) 1985-12-31
CA1127156A (en) 1982-07-06
ES8103740A1 (es) 1981-03-16
FI69841C (fi) 1986-05-26
JPS55370A (en) 1980-01-05
NZ190293A (en) 1980-11-28
IE790872L (en) 1978-10-27
ATA291379A (de) 1983-12-15
ZA791944B (en) 1980-04-30
FI791350A7 (fi) 1979-10-28
CS226185B2 (en) 1984-03-19
DE2963600D1 (en) 1982-10-28

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