ES8101075A1 - Un metodo de preparar nuevas espiro (dibenzo (b,f)oxepinpi- peridinas) - Google Patents

Un metodo de preparar nuevas espiro (dibenzo (b,f)oxepinpi- peridinas)

Info

Publication number
ES8101075A1
ES8101075A1 ES487451A ES487451A ES8101075A1 ES 8101075 A1 ES8101075 A1 ES 8101075A1 ES 487451 A ES487451 A ES 487451A ES 487451 A ES487451 A ES 487451A ES 8101075 A1 ES8101075 A1 ES 8101075A1
Authority
ES
Spain
Prior art keywords
oxepin
dibenz
methods
spiro
piperidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487451A
Other languages
English (en)
Other versions
ES487451A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES487451A0 publication Critical patent/ES487451A0/es
Publication of ES8101075A1 publication Critical patent/ES8101075A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE ESPIRO-DIBENZO (B,F) OXEPIN.PIPERIDINAS). CONSISTE EN CICLOACILAR UN COMPUESTO DE FORMULA GENERAL (I), EN QUE R ES METILO O UN RADICAL ALCANOILO DE 2 A 6 ATOMOS DE CARBONO, Y Z ES HALOGENO O EL GRUPO HIDROXILO CON UN CATALIZADOR DE LEWIS. SE OBTIENE UN COMPUESTO DE FORMULA GENERAL II. *FORMULA* ANALGESICOS, TRANQUILIZANTES Y ANTICONVULSIVOS.
ES487451A 1979-01-10 1980-01-04 Un metodo de preparar nuevas espiro (dibenzo (b,f)oxepinpi- peridinas) Expired ES8101075A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/002,348 US4198418A (en) 1979-01-10 1979-01-10 Spiro[dibenz(b,f)oxepin-piperidine]s

Publications (2)

Publication Number Publication Date
ES487451A0 ES487451A0 (es) 1980-12-01
ES8101075A1 true ES8101075A1 (es) 1980-12-01

Family

ID=21700360

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487451A Expired ES8101075A1 (es) 1979-01-10 1980-01-04 Un metodo de preparar nuevas espiro (dibenzo (b,f)oxepinpi- peridinas)

Country Status (10)

Country Link
US (1) US4198418A (es)
EP (1) EP0016261B1 (es)
JP (1) JPS5594387A (es)
AR (1) AR229153A1 (es)
AT (1) ATE2147T1 (es)
AU (1) AU534512B2 (es)
CA (1) CA1142940A (es)
DE (1) DE2964444D1 (es)
ES (1) ES8101075A1 (es)
ZA (1) ZA80115B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100190764A1 (en) * 2007-07-27 2010-07-29 Glaxo Group Limited Novel compounds
GB0714713D0 (en) * 2007-07-27 2007-09-05 Glaxo Group Ltd Novel compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI45449C (fi) * 1965-04-29 1972-06-12 Ciba Geigy Ag Menetelmä uusien faramokologisesti aktiivisten 11-(1-piperatsinyyli)-d ibentso/b,f/tiepin-10(11H)-onien valmistamiseksi
FR1559622A (es) * 1967-08-17 1969-03-14
CH539044A (de) * 1967-10-06 1973-08-31 Gnii Orch Poluproduktov I Kras Verfahren zur Herstellung quaternärer Ammoniumsalze von 1,3-Bis-(aminomethyl)-imidazolidonen
AT306036B (de) * 1971-07-05 1973-03-26 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von Methylpiperazinderivaten und deren Salzen
GB1434486A (en) * 1974-02-04 1976-05-05 Ici Ltd Thioxanthene derivatives
GB1447583A (en) * 1974-02-04 1976-08-25 Ici Ltd Xanthene derivatives

Also Published As

Publication number Publication date
EP0016261B1 (de) 1982-12-29
EP0016261A1 (de) 1980-10-01
AU5449080A (en) 1980-07-17
ATE2147T1 (de) 1983-01-15
AR229153A1 (es) 1983-06-30
JPS5594387A (en) 1980-07-17
ZA80115B (en) 1980-12-31
ES487451A0 (es) 1980-12-01
US4198418A (en) 1980-04-15
AU534512B2 (en) 1984-02-02
CA1142940A (en) 1983-03-15
DE2964444D1 (en) 1983-02-03

Similar Documents

Publication Publication Date Title
PT72007A (en) Process for preparing novel chloro- and alkoxy-substituted-2,4-diaminoquinazolines
IE40298B1 (en) Substitud 1,3-dihydrospiro(isobenzofuran)s
IL60904A0 (en) Preparation of 1a-hydrovitamin d compounds form 1a-hydroxy-3,5-cyclovitamin d compounds
DE3060568D1 (en) Process for the preparation of 4,5-perfluoro-1,3-dioxolanes
DE3067926D1 (en) Stabilising compounds, process for their preparation and compositions containing them
NZ193324A (en) Preparation of n2-phenyl-2,6-diaminonebularines
ES458127A1 (es) Un procedimiento de preparacion de 1,3-dihidro-heteroariles-piro (isobensofuranos).
AU537792B2 (en) Disposable article of improved colour, composition and method for making same
ES8101075A1 (es) Un metodo de preparar nuevas espiro (dibenzo (b,f)oxepinpi- peridinas)
ZA80116B (en) Spiro(dibenz(b,f)thiepin-piperidines
EP0023022A3 (en) Coumarine compounds, processes for their manufacture as well as the intermediate products used perse and their utilisation for the dyeing or printing of textiles
DE3067981D1 (en) Substituted norbornanone acetals, process for preparing the same, and perfume compositions containing the same
DE3060256D1 (en) Process for the preparation of n-aryl-oxazolidine-2,4-diones
ZA80970B (en) Useful guanidinothiazole compounds,process for preparing them and medical compositions containing them
ES455245A1 (es) Un procedimiento para la preparacion de nuevos 1,3-dihidro- 1'-dimetilfosfimilalcohil-3-fenislespino (isobenzofurano)s.
ES459821A1 (es) Un procedimiento para la preparacion de nuevas 1,3-dihidro- espiro (isobenzofuran-1,4'-piperidinas).
DE3069793D1 (en) Method for the introduction of an oxygen-containing functional group into ansamycines, compounds thus obtained, and pharmaceutical compositions containing them
AU5709380A (en) 5-aryl-1-hetero-1h-1,4-benzodiazepines
DE3067531D1 (en) Process for the preparation of 1,4-benzodiazepines
HU187262B (en) Process for preparing new tetrahydro-1,4-benzodiazepin-2-ones
PH17082A (en) 2,1,3-benzothiadiazoles useful as tranquilizers
HU178519B (en) Process for transforming /+/-enanthiomere into /-/-enanthiomere of 1-bracket-3,4-dimethoxyphenyl-bracket closed-5-ethyl-7,8-dimethoxy-4-ethyl-5h-2,3-benzodiazepine
AU548447B2 (en) Traveller ring
YU39684B (en) Process for preparing 7-chloro-2,3-dihydro-1-methyl-5-phenyl-1h-1,4-benzodiazepine
YU40741B (en) Process for preparing substituted 1,4-benzodiazepines