ES8101890A1 - Un procedimiento para preparar una forma de dosificacion de una vacuna de una cepa avirulenta atenuada de bordetella - bronchiseptica. - Google Patents

Un procedimiento para preparar una forma de dosificacion de una vacuna de una cepa avirulenta atenuada de bordetella - bronchiseptica.

Info

Publication number
ES8101890A1
ES8101890A1 ES487816A ES487816A ES8101890A1 ES 8101890 A1 ES8101890 A1 ES 8101890A1 ES 487816 A ES487816 A ES 487816A ES 487816 A ES487816 A ES 487816A ES 8101890 A1 ES8101890 A1 ES 8101890A1
Authority
ES
Spain
Prior art keywords
vaccine
procedure
bronchiseptica
bordetella
sterile water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487816A
Other languages
English (en)
Other versions
ES487816A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iowa State University Research Foundation Inc
Original Assignee
Iowa State University Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/967,477 external-priority patent/US4225583A/en
Priority claimed from EP79810169A external-priority patent/EP0012718B1/en
Application filed by Iowa State University Research Foundation Inc filed Critical Iowa State University Research Foundation Inc
Publication of ES487816A0 publication Critical patent/ES487816A0/es
Publication of ES8101890A1 publication Critical patent/ES8101890A1/es
Expired legal-status Critical Current

Links

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCEDIMIENTO DE DOSIFICACION DE UNA VACUNA DE UNA CEPA AVIRULENTA ATENUADA DE BORDETELLA BRONCHISEPTICA. CONSTA DE LAS SIGUIENTES OPERACIONES: 1) CULTIVO EN UN MEDIO NUTRIENTE ACUOSO DE LA CEPA BORDETELLA BRONCHISEPTICA ATCC N. 31437, O DE UNA CEPA DERIVADA DE ESTA. SE OBTIENE UNA SUSPENSION ACUOSA DE UNA CONCENTRACION DE AL MENOS 1 X 10 ELEVADO A 7 CELULAS VIABLES POR MILILITRO. 2) ADICION DE UNA SOLUCION ACUOSA DE UN CRIOPROTECTOR MICROBIOLOGICO Y MEDIOS DE ESTABILIZACION. 3) LIOFILIZACION DE LA SUSPENSION CELULAR DILUIDA. 4) INTRODUCCION DE UNA CANTIDAD MEDIDA DE LAS CELULAS LIOFILIZADAS EN UN VIAL DE VACUNA PARA EL ALMACENAMIENTO Y TRANSPORTE DE LA VACUNA. SE AÑADE AGUA ESTERIL EN UNA PROPORCION DE AL MENOS UN 25 POR 100 MENOS QUE EL VOLUMEN DE AGUA RETIRADA POR LA LIOFILIZACION. EL AGUA ESTERIL CONTIENE UN AGENTE HUMECTANTE ANIONICO O NO IONICO. TRATAMIENTO DE RINITIS ATROFICA EN CERDOS Y DE TOS CANINA (TRAQUEOBRONQUITIS) EN PERROS.
ES487816A 1978-12-07 1980-01-18 Un procedimiento para preparar una forma de dosificacion de una vacuna de una cepa avirulenta atenuada de bordetella - bronchiseptica. Expired ES8101890A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96747878A 1978-12-07 1978-12-07
US05/967,477 US4225583A (en) 1978-12-07 1978-12-07 Intra-respiratory vaccine for prevention of Bordetella bronchiseptica infection and method of use
EP79810169A EP0012718B1 (en) 1978-12-07 1979-11-30 Intra-respiratory vaccine, modified bacteria strain used in it, vaccine dose form and process for preparing it

Publications (2)

Publication Number Publication Date
ES487816A0 ES487816A0 (es) 1980-12-16
ES8101890A1 true ES8101890A1 (es) 1980-12-16

Family

ID=27224630

Family Applications (2)

Application Number Title Priority Date Filing Date
ES486579A Expired ES486579A1 (es) 1978-12-07 1979-12-04 Un procedimiento para preparar una vacuna intra-respiratoria
ES487816A Expired ES8101890A1 (es) 1978-12-07 1980-01-18 Un procedimiento para preparar una forma de dosificacion de una vacuna de una cepa avirulenta atenuada de bordetella - bronchiseptica.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES486579A Expired ES486579A1 (es) 1978-12-07 1979-12-04 Un procedimiento para preparar una vacuna intra-respiratoria

Country Status (2)

Country Link
AT (1) ATE212T1 (es)
ES (2) ES486579A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物

Also Published As

Publication number Publication date
ES486579A1 (es) 1980-10-01
ES487816A0 (es) 1980-12-16
ATE212T1 (de) 1981-10-15

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