ES8105251A1 - Procedimiento de preparacion de derivados de la 4'-hidroxia-cetofenona de interes farmacologico - Google Patents

Procedimiento de preparacion de derivados de la 4'-hidroxia-cetofenona de interes farmacologico

Info

Publication number
ES8105251A1
ES8105251A1 ES492682A ES492682A ES8105251A1 ES 8105251 A1 ES8105251 A1 ES 8105251A1 ES 492682 A ES492682 A ES 492682A ES 492682 A ES492682 A ES 492682A ES 8105251 A1 ES8105251 A1 ES 8105251A1
Authority
ES
Spain
Prior art keywords
translation
procedure
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492682A
Other languages
English (en)
Other versions
ES492682A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Fides SA
Original Assignee
Laboratorios Martin Cuatrecasas SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Martin Cuatrecasas SA filed Critical Laboratorios Martin Cuatrecasas SA
Priority to ES492682A priority Critical patent/ES492682A0/es
Publication of ES8105251A1 publication Critical patent/ES8105251A1/es
Publication of ES492682A0 publication Critical patent/ES492682A0/es
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE LA 4''HIDROXIACETOFENONA. CONSISTE EN HACER REACCIONAR LA 4''-HIDROACETOFENONA CON LA EPICLORHIDRINA EN PRESENCIA DE UN ALCALI FUERTE CON HIDROXIDO SODICO, O EN FORMA DE SAL METALICA DE LA 4''-HIDROXIACETOFENONA Y HACERLA REACCIONAR <<A POSTERIORI>> CON LA EPICLORHIDRINA, OBTENIENDOSE EN AMBOS CASOS EL DERIVADO 4''-(2,3-EPOXIPROPAN-1-OXI)ACETOFENONA. A CONTINUACION EL PRODUCTO OBTENIDO SE HACE REACCIONAR CON LA ISOPOPILAMINA, OBTENIENDOSE LAS 4''-(2-HIDROXI-3-ISOPROPILAMINOPROPAN-1-OXI)ACETOFENONA. LA MODIFICACION DE LOS PRODUCTOS OBTENIDOS SE REALIZA TRANSFORMANDO SU RADICAL CETONICO CON ESTER, MEDIANTE NITRATO DE TALIO (III), PARA OBTENER OTROS ESTERES. LOS ESTERES SE PUEDEN TRANSFORMAR EN AMIDAS MEDIANTE AMONOLISIS. BLOQUEANTE SELECTIVO DE LOS RECEPTORES BETA-ADRENERGICOS.
ES492682A 1980-06-23 1980-06-23 Procedimiento de preparacion de derivados de la 4'-hidroxia-cetofenona de interes farmacologico Granted ES492682A0 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES492682A ES492682A0 (es) 1980-06-23 1980-06-23 Procedimiento de preparacion de derivados de la 4'-hidroxia-cetofenona de interes farmacologico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES492682A ES492682A0 (es) 1980-06-23 1980-06-23 Procedimiento de preparacion de derivados de la 4'-hidroxia-cetofenona de interes farmacologico

Publications (2)

Publication Number Publication Date
ES8105251A1 true ES8105251A1 (es) 1981-06-01
ES492682A0 ES492682A0 (es) 1981-06-01

Family

ID=8480663

Family Applications (1)

Application Number Title Priority Date Filing Date
ES492682A Granted ES492682A0 (es) 1980-06-23 1980-06-23 Procedimiento de preparacion de derivados de la 4'-hidroxia-cetofenona de interes farmacologico

Country Status (1)

Country Link
ES (1) ES492682A0 (es)

Also Published As

Publication number Publication date
ES492682A0 (es) 1981-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970612