ES8106232A1 - Un procedimiento para la manufactura de una tableta recu- bierta de azucar para uso medico - Google Patents
Un procedimiento para la manufactura de una tableta recu- bierta de azucar para uso medicoInfo
- Publication number
- ES8106232A1 ES8106232A1 ES493845A ES493845A ES8106232A1 ES 8106232 A1 ES8106232 A1 ES 8106232A1 ES 493845 A ES493845 A ES 493845A ES 493845 A ES493845 A ES 493845A ES 8106232 A1 ES8106232 A1 ES 8106232A1
- Authority
- ES
- Spain
- Prior art keywords
- sugar
- coated tablet
- pharmaceutical material
- soluble pharmaceutical
- tablet containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008298 dragée Substances 0.000 title abstract 2
- 239000000463 material Substances 0.000 title abstract 2
- 239000007940 sugar coated tablet Substances 0.000 title abstract 2
- 239000011247 coating layer Substances 0.000 abstract 2
- 238000009495 sugar coating Methods 0.000 abstract 2
- 229920003086 cellulose ether Polymers 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
PROCEDIMIENTO DE FABRICACION DE UNA TABLETA PARA USO MEDICO, CON INTERPOSICION, ENTRE EL NUCLEO Y EL RECUBRIMIENTO EXTERIOR DE AZUCAR, DE UNA PELICULA PROTECTORA. LA PASTILLA, PREPARADA CONVENCIONALMENTE, TIENE UN NUCLEO QUE CONTIENE PRODUCTOS FARMACEUTICOS SOLUBLES EN GRASA, DE BAJO PUNTO DE FUSION, INFERIOR A 70 GC, SELECCIONADOS ENTRE EL GRUPO FORMADO POR COENZIMA Q, VITAMINA K, VITAMINA E Y DERIVADOS. SE PREPARA UNA SOLUCION, DISOLVIENDO AL MENOS UN ETER CELULOSICO, GENERALMENTE HIDROXIPROPILCELULOSA, Y UN PLASTIFICANTE, EN AGUA O AGUA Y ETANOL. SE PULVERIZA DICHA SOLUCION SOBRE EL NUCLEO, BIEN POR FLUIDIFICACION O POR SIMPLE PULVERIZACION MIENTRAS SE HACEN RODAR LAS PASTILLAS POR UNA BANDEJA, SECANDOSE A CONTINUACION, Y RECUBRIENDOLAS FINALMENTE CON AZUCAR; LA PELICULA DE ETER CELULOSICO APLICADA TIENE UN ESPESOR COMPRENDIDO ENTRE 0,02 MM. Y 0,3 MM. LA PELICULA APLICADA EVITA QUE LAS SUSTANCIAS DEL NUCLEO PASEN A LA CAPA DE RECUBRIMIENTO DE AZUCAR PRODUCIENDO UNA DESCOMPOSICION DE LASMISMAS Y UN OSCURECIMIENTO DE LA PASTILLA, O BIEN SE DISMINUYA SU SOLUBILIDAD. D
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9667779A JPS5620513A (en) | 1979-07-31 | 1979-07-31 | Sugar-coated tablet containing fat-soluble drug |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES493845A0 ES493845A0 (es) | 1981-08-01 |
| ES8106232A1 true ES8106232A1 (es) | 1981-08-01 |
Family
ID=14171420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES493845A Expired ES8106232A1 (es) | 1979-07-31 | 1980-07-30 | Un procedimiento para la manufactura de una tableta recu- bierta de azucar para uso medico |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4421738A (es) |
| EP (1) | EP0023327B1 (es) |
| JP (1) | JPS5620513A (es) |
| CA (1) | CA1160568A (es) |
| DE (1) | DE3068188D1 (es) |
| ES (1) | ES8106232A1 (es) |
| PH (1) | PH16829A (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4713243A (en) * | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
| USRE33093E (en) * | 1986-06-16 | 1989-10-17 | Johnson & Johnson Consumer Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
| ES2061623T3 (es) * | 1987-03-02 | 1994-12-16 | Brocades Pharma Bv | Procedimiento para la obtencion de una composicion farmaceutica y un granulado farmaceutico. |
| NO883326L (no) * | 1987-08-11 | 1989-02-13 | Bayer Ag | Dhp-retard-tilberedning. |
| NZ233403A (en) | 1989-04-28 | 1992-09-25 | Mcneil Ppc Inc | Simulated capsule-like medicament |
| JP2845342B2 (ja) * | 1990-04-28 | 1999-01-13 | 大正製薬株式会社 | ビタミンd▲下3▼誘導体含有固形製剤組成物 |
| JP3703481B2 (ja) * | 1992-01-17 | 2005-10-05 | バーウィンド・ファーマスーティカル・サーヴィスィーズ・インコーポレーテッド | セルロース重合体およびラクトースに基づくフィルム被覆および被覆組成物 |
| US5705183A (en) * | 1994-11-16 | 1998-01-06 | Phillips Company | Cotton candy coated medication and a method for making and administering the same |
| FR2736550B1 (fr) * | 1995-07-14 | 1998-07-24 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule |
| US5985325A (en) * | 1997-06-13 | 1999-11-16 | American Home Products Corporation | Rapamycin formulations for oral administration |
| US6432448B1 (en) | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
| US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
| US6254888B1 (en) | 2000-01-28 | 2001-07-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for coating pharmaceutical dosage forms |
| US6699315B2 (en) | 2000-11-28 | 2004-03-02 | Fmc Corporation | Edible PGA coating composition |
| US6932861B2 (en) | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
| US20060147542A1 (en) * | 2004-12-24 | 2006-07-06 | Tadao Ono | Solid preparation containing reduced coenzyme Q10 and method for producing the same |
| ES2563929T3 (es) * | 2004-12-24 | 2016-03-16 | Kaneka Corporation | Preparación sólida que comprende coenzima Q10 reducida y proceso para la producción de la misma |
| JPWO2006129668A1 (ja) * | 2005-05-30 | 2009-01-08 | 明治製菓株式会社 | 糖衣を施した丸剤 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2693436A (en) * | 1951-02-27 | 1954-11-02 | Upjohn Co | Coating material for tablets and coated tablets |
| FR1101398A (fr) * | 1953-05-28 | 1955-10-05 | Philips Nv | Procédé de préparation de pilules enrobées, notamment de pilules dragéifiées |
| US2881085A (en) * | 1953-11-09 | 1959-04-07 | Abbott Lab | Thin film coating for tablets and the like |
| US2816062A (en) * | 1954-05-27 | 1957-12-10 | Univ Illinois | Hydroxyethyl cellulose tablet coating |
| US2925365A (en) * | 1957-11-27 | 1960-02-16 | Smith Kline French Lab | Coloring solid pharmaceutical forms and compositions therefor |
| US3043747A (en) * | 1958-10-22 | 1962-07-10 | Upjohn Co | Tablets coated with carboxymethylcellulose shellac composition |
| US3096248A (en) * | 1959-04-06 | 1963-07-02 | Rexall Drug & Chemical Company | Method of making an encapsulated tablet |
| US3054724A (en) * | 1960-05-12 | 1962-09-18 | Smith Kline French Lab | Coloring discrete solids and compositions therefor |
| DE1228757B (de) * | 1962-06-28 | 1966-11-17 | Haessle Ab | Verfahren zur Herstellung eines in Wasser und Magensaft rasch zerfallenden UEberzuges auf festen Arzneiformen |
| US3185626A (en) * | 1963-03-06 | 1965-05-25 | Sterling Drug Inc | Tablet coating method |
| US3361631A (en) * | 1963-09-30 | 1968-01-02 | Sandoz Ag | Method of sugar coating pharmaceutical tablets |
| US3383236A (en) * | 1964-04-17 | 1968-05-14 | Merck & Co Inc | Continuous pharmaceutical film coating process |
| US3406031A (en) * | 1964-08-27 | 1968-10-15 | Geigy Chem Corp | Pharmaceutical dosage unit form coating process |
| US3256111A (en) * | 1964-12-04 | 1966-06-14 | Abbott Lab | Method for coating tablets |
| NL6601426A (es) * | 1965-02-12 | 1966-08-15 | ||
| US3981984A (en) * | 1968-04-01 | 1976-09-21 | Colorcon Incorporated | Color film coating of tablets and the like |
| JPS4836321A (es) * | 1971-09-17 | 1973-05-29 | ||
| JPS5610287B2 (es) * | 1973-02-16 | 1981-03-06 | ||
| JPS50129727A (es) * | 1974-04-04 | 1975-10-14 | ||
| ES438635A1 (es) * | 1974-06-24 | 1977-02-16 | Shinetsu Chemical Co | Procedimiento para el revestimiento de moldes solidos de do-sificacion. |
| JPS51123815A (en) * | 1975-04-22 | 1976-10-28 | Shin Etsu Chem Co Ltd | A process for preparing coated solid medicines |
| JPS52151717A (en) * | 1976-06-09 | 1977-12-16 | Shionogi & Co Ltd | Sugar coating on solid preparations |
-
1979
- 1979-07-31 JP JP9667779A patent/JPS5620513A/ja active Pending
-
1980
- 1980-07-17 PH PH24307A patent/PH16829A/en unknown
- 1980-07-18 DE DE8080104247T patent/DE3068188D1/de not_active Expired
- 1980-07-18 EP EP80104247A patent/EP0023327B1/en not_active Expired
- 1980-07-30 ES ES493845A patent/ES8106232A1/es not_active Expired
- 1980-07-31 CA CA000357454A patent/CA1160568A/en not_active Expired
-
1982
- 1982-03-18 US US06/359,407 patent/US4421738A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES493845A0 (es) | 1981-08-01 |
| JPS5620513A (en) | 1981-02-26 |
| EP0023327A2 (en) | 1981-02-04 |
| PH16829A (en) | 1984-03-06 |
| DE3068188D1 (en) | 1984-07-19 |
| EP0023327B1 (en) | 1984-06-13 |
| CA1160568A (en) | 1984-01-17 |
| EP0023327A3 (en) | 1981-10-21 |
| US4421738A (en) | 1983-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |