ES8200663A1 - Un metodo para la produccion industrial de n-(4-piridilme- til)-benzamidas - Google Patents
Un metodo para la produccion industrial de n-(4-piridilme- til)-benzamidasInfo
- Publication number
- ES8200663A1 ES8200663A1 ES492686A ES492686A ES8200663A1 ES 8200663 A1 ES8200663 A1 ES 8200663A1 ES 492686 A ES492686 A ES 492686A ES 492686 A ES492686 A ES 492686A ES 8200663 A1 ES8200663 A1 ES 8200663A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- benzamides
- pyridylmethyl
- production
- phenylsulfonylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- -1 sulfonylamino, phenyl Chemical group 0.000 abstract 2
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003368 amide group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE N-(4-PIRIDILMETIL)-BENZAMIDAS. CONSTA DE LAS SIGUIENTES ETAPAS: 1. REACCION DE UN ACIDO SUSTITUIDO (I) CON LA 4-AMINOMETILPIRIDINA EN PRESENCIA DE UN AGENTE DE CONDENSACION EN EL SENO DE UN DISOLVENTE TAL COMO EL CLORURO DE METILENO; LA TEMPERATURA DE REACCION ESTA COMPRENDIDA ENTRE 80 C Y LA PROPIA DE EBULLICION DEL DISOLVENTE. 2. FINALIZADA LA REACCION SE SEPARAN POR FILTRACION LOS SUBPRODUCTOS SOLIDOS. 3. EVAPORACION DEL DISOLVENTE HASTA SEQUEDAD, 4. CRISTALIZACION DEL RESIDUO CONSTITUIDO POR EL PRODUCTO Y EL DISOLVENTE. SE OBTIENE EL COMPUESTO DE FORMULA GENERAL (II),
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES492686A ES8200663A1 (es) | 1980-06-23 | 1980-06-23 | Un metodo para la produccion industrial de n-(4-piridilme- til)-benzamidas |
| GB8116144A GB2078215B (en) | 1980-06-23 | 1981-05-27 | N-(4-pyridylmethyl)-benzamides and their production |
| PT73147A PT73147B (en) | 1980-06-23 | 1981-06-05 | Process for the production of n-(4-pyridyl-methyl)-benzamides |
| DE19813122700 DE3122700A1 (de) | 1980-06-23 | 1981-06-06 | "n-(4-pyridylmethyl)-benzamide und verfahren zu ihrer herstellung" |
| FR8112173A FR2485008A1 (fr) | 1980-06-23 | 1981-06-19 | Procede pour la production de n-(4 pyridylmethyl)-benzamides, composes obtenus et application a titre de medicaments |
| JP9644281A JPS5732266A (en) | 1980-06-23 | 1981-06-22 | Pyridylmethyl-benzamide derivative and manufacture |
| CH4122/81A CH651298A5 (de) | 1980-06-23 | 1981-06-22 | N-(4-pyridylmethyl)-benzamide und verfahren zu ihrer herstellung. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES492686A ES8200663A1 (es) | 1980-06-23 | 1980-06-23 | Un metodo para la produccion industrial de n-(4-piridilme- til)-benzamidas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES492686A0 ES492686A0 (es) | 1981-06-01 |
| ES8200663A1 true ES8200663A1 (es) | 1981-06-01 |
Family
ID=8480664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES492686A Expired ES8200663A1 (es) | 1980-06-23 | 1980-06-23 | Un metodo para la produccion industrial de n-(4-piridilme- til)-benzamidas |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5732266A (es) |
| CH (1) | CH651298A5 (es) |
| DE (1) | DE3122700A1 (es) |
| ES (1) | ES8200663A1 (es) |
| FR (1) | FR2485008A1 (es) |
| GB (1) | GB2078215B (es) |
| PT (1) | PT73147B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4500714A (en) * | 1981-10-15 | 1985-02-19 | Chugai Seiyaku Kabushiki Kaisha | 3-Substituted-ureido-N-pyridyl benzamides |
| AU567140B2 (en) * | 1984-01-06 | 1987-11-12 | Shionogi & Co., Ltd. | Sulphonamido-benzamide derivatives |
| GB9300083D0 (en) * | 1993-01-05 | 1993-03-03 | Roussel Lab Ltd | Chemical compounds |
| EA008948B1 (ru) | 2003-09-18 | 2007-10-26 | Басф Акциенгезельшафт | Новые сульфонамиды в качестве средств защиты растений |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1073961A (en) * | 1964-04-22 | 1967-06-28 | Far Eastern Detailers Ltd | Pyridine derivatives and their preparation |
| NL7416176A (nl) * | 1973-12-26 | 1975-06-30 | Upjohn Co | Werkwijze voor het bevorderen van de productie van endogene prostaglandinen door zoogdieren, alsmede werkwijze ter bereiding van daarbij te gebruiken preparaten. |
| DE2417763A1 (de) * | 1974-04-11 | 1975-10-30 | Bayer Ag | Carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2428673A1 (de) * | 1974-06-14 | 1976-01-02 | Bayer Ag | Carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1980
- 1980-06-23 ES ES492686A patent/ES8200663A1/es not_active Expired
-
1981
- 1981-05-27 GB GB8116144A patent/GB2078215B/en not_active Expired
- 1981-06-05 PT PT73147A patent/PT73147B/pt unknown
- 1981-06-06 DE DE19813122700 patent/DE3122700A1/de not_active Withdrawn
- 1981-06-19 FR FR8112173A patent/FR2485008A1/fr not_active Withdrawn
- 1981-06-22 JP JP9644281A patent/JPS5732266A/ja active Pending
- 1981-06-22 CH CH4122/81A patent/CH651298A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES492686A0 (es) | 1981-06-01 |
| GB2078215B (en) | 1984-06-06 |
| DE3122700A1 (de) | 1982-04-22 |
| GB2078215A (en) | 1982-01-06 |
| FR2485008A1 (fr) | 1981-12-24 |
| PT73147A (en) | 1981-07-01 |
| PT73147B (en) | 1982-07-16 |
| CH651298A5 (de) | 1985-09-13 |
| JPS5732266A (en) | 1982-02-20 |
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