ES8200695A1 - Procedimiento para la preparacion de cefalosporinas cromofo-ras - Google Patents
Procedimiento para la preparacion de cefalosporinas cromofo-rasInfo
- Publication number
- ES8200695A1 ES8200695A1 ES490683A ES490683A ES8200695A1 ES 8200695 A1 ES8200695 A1 ES 8200695A1 ES 490683 A ES490683 A ES 490683A ES 490683 A ES490683 A ES 490683A ES 8200695 A1 ES8200695 A1 ES 8200695A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- chromophoric
- utilisation
- compositions containing
- cephalosporin derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 4
- 229940124587 cephalosporin Drugs 0.000 title abstract 4
- 150000001780 cephalosporins Chemical class 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 108020004256 Beta-lactamase Proteins 0.000 abstract 2
- 102000006635 beta-lactamase Human genes 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2415/00—Assays, e.g. immunoassays or enzyme assays, involving penicillins or cephalosporins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Cephalosporin Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE CEFALOSPORINAS CROMOFORAS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (I) CON UN COMPUESTO (II). EL COMPUESTO OBTENIDO SE HACE REACCIONAR CON UN ACIDO CARBOXILICO O CON UN DERIVADO ACTIVADO DE DICHO ACIDO. LA REACCION SE EFECTUA EN MEDIO ACUOSO, AÑADIENDOSE OPCIONALMENTE DISOLVENTES MISCIBLES CON AGUA, TALES COMO METANOL, ETANOL, ISOPROPANOL, ACETONITRILO O ACETONA. LA TEMPERATURA DE REACCION OSCILA ENTRE 20 Y 80 C. EL PH SE MANTIENE ENTRE 5 Y 8, CON AGITACION MEDIANTE ADICION DE SOLUCION SATURADA DE HIDROXIDO DE SODIO O DE BICARBONATO DE SODIO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792916433 DE2916433A1 (de) | 1979-04-24 | 1979-04-24 | Chromophore cephalosporine und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8200695A1 true ES8200695A1 (es) | 1981-11-01 |
| ES490683A0 ES490683A0 (es) | 1981-11-01 |
Family
ID=6069059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES490683A Granted ES490683A0 (es) | 1979-04-24 | 1980-04-18 | Procedimiento para la preparacion de cefalosporinas cromofo-ras |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US4353824A (es) |
| EP (1) | EP0018001B1 (es) |
| JP (1) | JPS55143994A (es) |
| AT (1) | ATE3551T1 (es) |
| AU (1) | AU532120B2 (es) |
| BE (1) | BE882964A (es) |
| CA (1) | CA1145743A (es) |
| CH (1) | CH650511A5 (es) |
| DE (2) | DE2916433A1 (es) |
| ES (1) | ES490683A0 (es) |
| FR (1) | FR2455050A1 (es) |
| GB (1) | GB2049681B (es) |
| IT (1) | IT1141298B (es) |
| ZA (1) | ZA802443B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3006889A1 (de) * | 1980-02-23 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Chromogene cephalosporine und verfahren zu ihrer herstellung |
| DE3019451A1 (de) * | 1980-05-21 | 1981-11-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und reagens zur bestimmung von (beta) -lactamasen |
| US4555396A (en) * | 1982-12-22 | 1985-11-26 | Eastman Kodak Company | Use of pyrylium and thiapyrylium compounds as biological stains |
| US4840784A (en) * | 1982-12-22 | 1989-06-20 | Eastman Kodak Company | Use of pyrylium and thiapyrylium compounds as biological stains |
| US4568637A (en) * | 1983-08-10 | 1986-02-04 | Whittaker M.A. Bioproducts, Inc. | Method of determining antibiotics in biological liquids |
| US4692443A (en) * | 1983-10-17 | 1987-09-08 | Eli Lilly And Company | 3-bicyclicpyridinium-methyl cephalosporins |
| US4760018A (en) * | 1985-06-17 | 1988-07-26 | Penicillin Assays, Inc. | Rapid method for the detection of beta-lactamase in body fluids |
| US4764462A (en) * | 1985-08-23 | 1988-08-16 | Georgetown University | Detectably labeled cephalosporin assay for beta-lactamase |
| US5096668A (en) * | 1990-04-26 | 1992-03-17 | Difco Laboratories | Diagnostic test slide |
| US5338843A (en) * | 1992-01-30 | 1994-08-16 | Becton, Dickinson And Company | Fluorogenic and chromogenic β-lactamase substrates |
| US5411893A (en) * | 1993-03-15 | 1995-05-02 | Difco Laboratories | Dry slide for diagnostic tests |
| US5741657A (en) * | 1995-03-20 | 1998-04-21 | The Regents Of The University Of California | Fluorogenic substrates for β-lactamase and methods of use |
| US5955604A (en) * | 1996-10-15 | 1999-09-21 | The Regents Of The University Of California | Substrates for β-lactamase and uses thereof |
| US6031094A (en) * | 1998-07-23 | 2000-02-29 | The Regents Of The University Of California | Beta-lactam substrates and uses thereof |
| DE10029808C1 (de) | 2000-06-16 | 2001-11-29 | Daimler Chrysler Ag | Abgasturbolader für eine Brennkraftmaschine |
| US20020177229A1 (en) * | 2001-01-19 | 2002-11-28 | Ivo Piest | Swap/counter selection: a rapid cloning method |
| WO2010016911A2 (en) * | 2008-08-06 | 2010-02-11 | The Texas A & M University System | Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics |
| FR2956866B1 (fr) * | 2010-03-01 | 2014-01-10 | Bio Rad Pasteur | Procede de detection en milieu liquide de bacteries resistantes aux cephalosporines de troisieme generation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4024134A (en) * | 1971-01-29 | 1977-05-17 | Glaxo Laboratories Limited | Syn isomers of cephalosporins having α-hydroximino- or α-acyloxyiminoacylamido groups at position-7 |
| BE789817A (fr) * | 1971-10-07 | 1973-04-06 | Glaxo Lab Ltd | Perfectionnements aux composes de cephalosporine |
| US4198504A (en) * | 1978-11-02 | 1980-04-15 | Bristol-Myers Company | [3-(Pyridinium)-7-(naphthyiridinyl carbonylamino)acetamido]cephalosporanic acid derivatives |
-
1979
- 1979-04-24 DE DE19792916433 patent/DE2916433A1/de not_active Withdrawn
-
1980
- 1980-04-18 ES ES490683A patent/ES490683A0/es active Granted
- 1980-04-18 AT AT80102106T patent/ATE3551T1/de not_active IP Right Cessation
- 1980-04-18 EP EP80102106A patent/EP0018001B1/de not_active Expired
- 1980-04-18 DE DE8080102106T patent/DE3063428D1/de not_active Expired
- 1980-04-21 CH CH3063/80A patent/CH650511A5/de not_active IP Right Cessation
- 1980-04-22 US US06/142,767 patent/US4353824A/en not_active Expired - Lifetime
- 1980-04-22 IT IT21564/80A patent/IT1141298B/it active
- 1980-04-23 CA CA000350446A patent/CA1145743A/en not_active Expired
- 1980-04-23 AU AU57721/80A patent/AU532120B2/en not_active Ceased
- 1980-04-23 ZA ZA00802443A patent/ZA802443B/xx unknown
- 1980-04-24 BE BE0/200363A patent/BE882964A/fr not_active IP Right Cessation
- 1980-04-24 FR FR8009202A patent/FR2455050A1/fr active Granted
- 1980-04-24 GB GB8013508A patent/GB2049681B/en not_active Expired
- 1980-04-24 JP JP5530580A patent/JPS55143994A/ja active Granted
-
1982
- 1982-07-06 US US06/395,135 patent/US4448880A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE3551T1 (de) | 1983-06-15 |
| US4448880A (en) | 1984-05-15 |
| CA1145743A (en) | 1983-05-03 |
| BE882964A (fr) | 1980-10-24 |
| FR2455050B1 (es) | 1983-05-13 |
| US4353824A (en) | 1982-10-12 |
| FR2455050A1 (fr) | 1980-11-21 |
| ZA802443B (en) | 1981-04-29 |
| EP0018001A2 (de) | 1980-10-29 |
| DE3063428D1 (en) | 1983-07-07 |
| AU5772180A (en) | 1980-10-30 |
| IT1141298B (it) | 1986-10-01 |
| AU532120B2 (en) | 1983-09-15 |
| JPS55143994A (en) | 1980-11-10 |
| GB2049681A (en) | 1980-12-31 |
| DE2916433A1 (de) | 1980-11-13 |
| GB2049681B (en) | 1983-04-27 |
| ES490683A0 (es) | 1981-11-01 |
| EP0018001B1 (de) | 1983-05-25 |
| CH650511A5 (de) | 1985-07-31 |
| EP0018001A3 (en) | 1980-11-26 |
| IT8021564A0 (it) | 1980-04-22 |
| JPH021148B2 (es) | 1990-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |