ES8201545A1 - Procedimiento para la preparacion de 2,2'-dihidroxi-5,5'-me-tilen-di-(acido para-toluenosulfonico) y sus sales - Google Patents
Procedimiento para la preparacion de 2,2'-dihidroxi-5,5'-me-tilen-di-(acido para-toluenosulfonico) y sus salesInfo
- Publication number
- ES8201545A1 ES8201545A1 ES497410A ES497410A ES8201545A1 ES 8201545 A1 ES8201545 A1 ES 8201545A1 ES 497410 A ES497410 A ES 497410A ES 497410 A ES497410 A ES 497410A ES 8201545 A1 ES8201545 A1 ES 8201545A1
- Authority
- ES
- Spain
- Prior art keywords
- acid
- cresol
- salts
- converted
- medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- ZWZGXLKXKAPXMZ-UHFFFAOYSA-N 2,2'-dihydroxy-3,3'-dimethoxy-5,5'-dipropyldiphenylmethane Chemical class COC1=CC(CCC)=CC(CC=2C(=C(OC)C=C(CCC)C=2)O)=C1O ZWZGXLKXKAPXMZ-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 18
- 150000003839 salts Chemical class 0.000 abstract 11
- 239000002253 acid Substances 0.000 abstract 7
- 229960004279 formaldehyde Drugs 0.000 abstract 6
- 235000019256 formaldehyde Nutrition 0.000 abstract 6
- GCFPFWRHYINTRX-UHFFFAOYSA-N 2-hydroxy-4-methylbenzenesulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C(O)=C1 GCFPFWRHYINTRX-UHFFFAOYSA-N 0.000 abstract 3
- AGAPQTXXLGLKFS-UHFFFAOYSA-N 5-hydroxy-2-[(4-hydroxy-5-methyl-2-sulfophenyl)methyl]-4-methylbenzenesulfonic acid Chemical compound C1=C(O)C(C)=CC(CC=2C(=CC(O)=C(C)C=2)S(O)(=O)=O)=C1S(O)(=O)=O AGAPQTXXLGLKFS-UHFFFAOYSA-N 0.000 abstract 2
- RLSSMJSEOOYNOY-UHFFFAOYSA-N m-cresol Chemical compound CC1=CC=CC(O)=C1 RLSSMJSEOOYNOY-UHFFFAOYSA-N 0.000 abstract 2
- FURVMUXSTJNEMY-UHFFFAOYSA-N 2-hydroxy-5-(hydroxymethyl)-4-methylbenzenesulfonic acid Chemical compound CC1=CC(O)=C(S(O)(=O)=O)C=C1CO FURVMUXSTJNEMY-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical group OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 2,2''-DIHIDROXI-5,5''-METILENDI-(ACIDO-P-TOLUENOSULFONICO) Y SUS SALES. CONSISTE EN LA REACCION DE ACIDO M-CRESOL-6-SULFONICO, Y/O SUS SALES, CON FORMALDEHIDO Y/O CON COMPUESTOS QUE LIBERAN FORMALDEHIDO. LA REACCION DE CONDENSACION CON EL FORMALDEHIDO SE LLEVA A CABO EN DISOLUCION ACUOSA A UNA TEMPERATURA COMPRENDIDA ENTRE 10 C Y 90 C. TAMBIEN SE PUEDE PARTIR DE LA SAL AMONICA O SODICA DEL ACIDO M-CRESOL-6-SULFONICO, REALIZANDO EN ESTE CAXO LA CONDENSACION CON FORMALDEHIDO EN PRESENCIA DE AMINAS ORGANICAS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS EFECTOS ASTRINGENTES, BACTERICIDA, TRICOMONACIDA, FUNGICIDA Y HEMOSTIPTICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1076379 | 1979-12-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8201545A1 true ES8201545A1 (es) | 1982-01-01 |
| ES497410A0 ES497410A0 (es) | 1982-01-01 |
Family
ID=4366580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497410A Granted ES497410A0 (es) | 1979-12-04 | 1980-12-03 | Procedimiento para la preparacion de 2,2'-dihidroxi-5,5'-me-tilen-di-(acido para-toluenosulfonico) y sus sales |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0029990B1 (es) |
| JP (1) | JPS56113754A (es) |
| AT (1) | ATE1523T1 (es) |
| AU (1) | AU535714B2 (es) |
| DE (1) | DE3060828D1 (es) |
| DK (1) | DK517580A (es) |
| ES (1) | ES497410A0 (es) |
| GR (1) | GR71617B (es) |
| IE (1) | IE50610B1 (es) |
| IL (1) | IL61600A (es) |
| NZ (1) | NZ195716A (es) |
| PL (1) | PL228235A1 (es) |
| PT (1) | PT72160B (es) |
| ZA (1) | ZA807544B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4605726B2 (ja) * | 1997-09-02 | 2011-01-05 | 日本曹達株式会社 | フェノール誘導体を成分化合物とする分子化合物 |
| FR2964316B1 (fr) * | 2010-09-03 | 2013-03-08 | Thierry Rouleau | Dispositif permettant d'obtenir une retraction gingivale par effet astringent et hemostatique associe a un effet de desinfection et d'auto elimination |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1518102C3 (de) * | 1964-03-09 | 1974-02-14 | Pabianickie Zaklady Farmaceutyczne Polfa Przedsiebiorstwo Panstwowe, Pabianice (Polen) | Verfahren zur Herstellung eines reinen wasserlöslichen für therapeutische Zwecke geeigneten Kondensationsproduktes aus m-Kresolsulfonsäure und Formaldehyd |
-
1980
- 1980-11-25 AT AT80107328T patent/ATE1523T1/de not_active IP Right Cessation
- 1980-11-25 EP EP80107328A patent/EP0029990B1/de not_active Expired
- 1980-11-25 DE DE8080107328T patent/DE3060828D1/de not_active Expired
- 1980-12-01 IL IL61600A patent/IL61600A/xx unknown
- 1980-12-02 NZ NZ195716A patent/NZ195716A/xx unknown
- 1980-12-02 AU AU64997/80A patent/AU535714B2/en not_active Ceased
- 1980-12-02 GR GR63531A patent/GR71617B/el unknown
- 1980-12-03 DK DK517580A patent/DK517580A/da not_active Application Discontinuation
- 1980-12-03 IE IE2519/80A patent/IE50610B1/en unknown
- 1980-12-03 ZA ZA00807544A patent/ZA807544B/xx unknown
- 1980-12-03 PL PL22823580A patent/PL228235A1/xx unknown
- 1980-12-03 ES ES497410A patent/ES497410A0/es active Granted
- 1980-12-04 JP JP17145380A patent/JPS56113754A/ja active Pending
- 1980-12-04 PT PT72160A patent/PT72160B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR71617B (es) | 1983-06-17 |
| IE50610B1 (en) | 1986-05-28 |
| AU535714B2 (en) | 1984-04-05 |
| IL61600A0 (en) | 1981-01-30 |
| DE3060828D1 (en) | 1982-10-28 |
| PT72160A (en) | 1981-01-01 |
| JPS56113754A (en) | 1981-09-07 |
| IE802519L (en) | 1981-06-04 |
| AU6499780A (en) | 1981-06-11 |
| ZA807544B (en) | 1981-11-25 |
| NZ195716A (en) | 1983-06-14 |
| ATE1523T1 (de) | 1982-09-15 |
| ES497410A0 (es) | 1982-01-01 |
| PT72160B (en) | 1982-07-05 |
| IL61600A (en) | 1984-06-29 |
| PL228235A1 (es) | 1982-08-02 |
| EP0029990B1 (de) | 1982-09-08 |
| DK517580A (da) | 1981-06-05 |
| EP0029990A1 (de) | 1981-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR2378023A1 (fr) | Procede de preparation d'oximes, nouveaux produits ainsi obtenus et leur application dans la synthese de composes d'acide cephemcarboxylique 3,7-disubstitue | |
| YU47063B (sh) | Postupak sinteze amikacina | |
| ES424859A1 (es) | Procedimiento para la obtencion de derivados de 2-arilamino-2-imidazolina. | |
| DE3060828D1 (en) | Biphenylmethane derivative, methods for its production and pharmaceutical compositions containing it | |
| ES488225A1 (es) | Procedimiento mejorado para la preparacion selectiva de iso-sorbida-5-nitrato | |
| GB1412240A (en) | Process for the preparation of 3- o,o-diethyldithiophosphorylmethyl -6-chlorobenzoxazolone | |
| KR830010059A (ko) | 방향족 아미노설폰산의 제조방법 | |
| Van Sant et al. | Formation of α-enaminoketones from α-azidoketones: An elimination of molecular nitrogen from α-azidoketones | |
| GB1308055A (en) | Process for the preparation of nitroximes and nitroketones | |
| GB1505020A (en) | Substituted 2-phenylimino-thiazolines a process for their preparation and their use as ectoparasiticides | |
| US2429835A (en) | N1(alpha, alpha-dimethyl-,beta-phenyl-propionyl) sulfanilamides | |
| GB1341204A (en) | Process for the manufacture of triarylmethane compounds | |
| FR2400033A1 (fr) | Procede de preparation des purine-arabinosides | |
| ES416971A1 (es) | Procedimiento para la preparacion de derivados isoquinoli- na. | |
| US2868804A (en) | Betaine ascorbate | |
| ES419202A1 (es) | Procedimiento para la preparacion de alfa-lactonas de aci- dos beta-(3-ceto-7 alfa-tioacil-). | |
| SU1077889A1 (ru) | Способ получени 2-втор-алкиламино-1,3,4-тиадиазолов | |
| SU1317890A1 (ru) | Способ получения сукцинимида | |
| ES461253A1 (es) | Un procedimiento para la produccion de dihidro-piran-3-ona. | |
| GB1254836A (en) | A process for the manufacture of phenazine derivatives | |
| JPS5653688A (en) | Novel cephalosporin derivative and its preparation | |
| GB1265764A (es) | ||
| ES422548A1 (es) | Un procedimiento para preparar el 3-(2-quinoxalinilmetilen)carbazato-n1,n4-bioxido de metilo. | |
| JPS54112894A (en) | Novel adenine derivative and its preparation | |
| GB1387130A (en) | Imidazolidinones and herbicidal compositions containing them |