ES8201567A1 - Epoxysuccinic Acid Derivatives - Google Patents

Epoxysuccinic Acid Derivatives

Info

Publication number
ES8201567A1
ES8201567A1 ES498734A ES498734A ES8201567A1 ES 8201567 A1 ES8201567 A1 ES 8201567A1 ES 498734 A ES498734 A ES 498734A ES 498734 A ES498734 A ES 498734A ES 8201567 A1 ES8201567 A1 ES 8201567A1
Authority
ES
Spain
Prior art keywords
epoxysuccinic acid
acid derivatives
derivatives
trans
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498734A
Other languages
Spanish (es)
Other versions
ES498734A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Publication of ES8201567A1 publication Critical patent/ES8201567A1/en
Publication of ES498734A0 publication Critical patent/ES498734A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel epoxysuccinic acid derivatives are provided of the formula:- < IMAGE > and non-toxic salts thereof, where R represents a lower alkyl group. These epoxysuccinic acid derivatives and their non-toxic salt are useful for inhibiting myocardial infarction. The derivatives may be made by reacting a leucine lower alkyl ester with a trans- epoxysuccinic acid mono-ester, or trans-epoxysuccinic acid itself.
ES498734A 1980-01-25 1981-01-22 PROCEDURE FOR OBTAINING AN ANTI-INFARCTION AGENT, MYOCARDIUM Granted ES498734A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP690780A JPS56104816A (en) 1980-01-25 1980-01-25 Preventive and remedy for caridac infarction

Publications (2)

Publication Number Publication Date
ES8201567A1 true ES8201567A1 (en) 1982-01-01
ES498734A0 ES498734A0 (en) 1982-01-01

Family

ID=11651300

Family Applications (1)

Application Number Title Priority Date Filing Date
ES498734A Granted ES498734A0 (en) 1980-01-25 1981-01-22 PROCEDURE FOR OBTAINING AN ANTI-INFARCTION AGENT, MYOCARDIUM

Country Status (7)

Country Link
JP (1) JPS56104816A (en)
BR (1) BR8100350A (en)
DE (1) DE3102486A1 (en)
ES (1) ES498734A0 (en)
FR (1) FR2474497A1 (en)
GB (1) GB2067999A (en)
IT (1) IT1141956B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1595168A (en) * 1977-03-03 1981-08-12 Taisho Pharmaceutical Co Ltd Expoxysuccinic acid derivatives

Also Published As

Publication number Publication date
JPS6365644B2 (en) 1988-12-16
ES498734A0 (en) 1982-01-01
JPS56104816A (en) 1981-08-20
GB2067999A (en) 1981-08-05
IT1141956B (en) 1986-10-08
FR2474497A1 (en) 1981-07-31
DE3102486A1 (en) 1981-11-19
BR8100350A (en) 1981-08-11
IT8119331A0 (en) 1981-01-26

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